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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleAdult Brain
Open Access

Automated Integration of Multimodal MRI for the Probabilistic Detection of the Central Vein Sign in White Matter Lesions

J.D. Dworkin, P. Sati, A. Solomon, D.L. Pham, R. Watts, M.L. Martin, D. Ontaneda, M.K. Schindler, D.S. Reich and R.T. Shinohara
American Journal of Neuroradiology October 2018, 39 (10) 1806-1813; DOI: https://doi.org/10.3174/ajnr.A5765
J.D. Dworkin
aFrom the Department of Biostatistics, Epidemiology, and Informatics (J.D.D., M.L.M., R.T.S.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
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P. Sati
bTranslational Neuroradiology Section (P.S., M.K.S., D.S.R.), National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland
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A. Solomon
cDepartments of Neurological Sciences (A.S.)
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D.L. Pham
eCenter for Neuroscience and Regenerative Medicine (D.L.P.), Henry M. Jackson Foundation, Bethesda, Maryland
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R. Watts
dRadiology (R.W.), Larner College of Medicine at the University of Vermont, Burlington, Vermont
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M.L. Martin
aFrom the Department of Biostatistics, Epidemiology, and Informatics (J.D.D., M.L.M., R.T.S.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
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D. Ontaneda
fMellen Center for Multiple Sclerosis Treatment and Research (D.O.), Cleveland Clinic, Cleveland, Ohio
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M.K. Schindler
bTranslational Neuroradiology Section (P.S., M.K.S., D.S.R.), National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland
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D.S. Reich
bTranslational Neuroradiology Section (P.S., M.K.S., D.S.R.), National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland
gDepartment of Neurology (D.S.R.), Johns Hopkins University School of Medicine, Baltimore, Maryland.
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R.T. Shinohara
aFrom the Department of Biostatistics, Epidemiology, and Informatics (J.D.D., M.L.M., R.T.S.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
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Article Information

vol. 39 no. 10 1806-1813
DOI 
https://doi.org/10.3174/ajnr.A5765
PubMed 
30213803

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received April 5, 2018
  • Accepted after revision June 25, 2018
  • Published online October 8, 2018.

Article Versions

  • Latest version (September 13, 2018 - 11:02).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2018 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org

Author Information

  1. J.D. Dworkina,
  2. P. Satib,
  3. A. Solomonc,
  4. D.L. Phame,
  5. R. Wattsd,
  6. M.L. Martina,
  7. D. Ontanedaf,
  8. M.K. Schindlerb,
  9. D.S. Reichb,g and
  10. R.T. Shinoharaa
  1. aFrom the Department of Biostatistics, Epidemiology, and Informatics (J.D.D., M.L.M., R.T.S.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
  2. bTranslational Neuroradiology Section (P.S., M.K.S., D.S.R.), National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland
  3. cDepartments of Neurological Sciences (A.S.)
  4. dRadiology (R.W.), Larner College of Medicine at the University of Vermont, Burlington, Vermont
  5. eCenter for Neuroscience and Regenerative Medicine (D.L.P.), Henry M. Jackson Foundation, Bethesda, Maryland
  6. fMellen Center for Multiple Sclerosis Treatment and Research (D.O.), Cleveland Clinic, Cleveland, Ohio
  7. gDepartment of Neurology (D.S.R.), Johns Hopkins University School of Medicine, Baltimore, Maryland.
  1. Please address correspondence to Jordan D. Dworkin, Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, 218 Blockley Hall, 423 Guardian Drive Philadelphia, PA, 19104; e-mail: jdwor{at}pennmedicine.upenn.edu; @jddwor
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Funding

  • National Institute of Mental Health

    R01 MH112847
  • National Institute of Neurological Disorders and Stroke

    R01 NS060910; R01 NS085211; R21 NS093349; Z01 NS003119
  • National Multiple Sclerosis Society

    RG-1507-05243; RG-1707-28586
  • National Institute of Biomedical Imaging and Bioengineering

    R01 EB017255

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Cite this article
J.D. Dworkin, P. Sati, A. Solomon, D.L. Pham, R. Watts, M.L. Martin, D. Ontaneda, M.K. Schindler, D.S. Reich, R.T. Shinohara
Automated Integration of Multimodal MRI for the Probabilistic Detection of the Central Vein Sign in White Matter Lesions
American Journal of Neuroradiology Oct 2018, 39 (10) 1806-1813; DOI: 10.3174/ajnr.A5765

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Automated Integration of Multimodal MRI for the Probabilistic Detection of the Central Vein Sign in White Matter Lesions
J.D. Dworkin, P. Sati, A. Solomon, D.L. Pham, R. Watts, M.L. Martin, D. Ontaneda, M.K. Schindler, D.S. Reich, R.T. Shinohara
American Journal of Neuroradiology Oct 2018, 39 (10) 1806-1813; DOI: 10.3174/ajnr.A5765
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