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Research ArticleADULT BRAIN
Open Access

Enhancing Brain Lesions during Acute Optic Neuritis and/or Longitudinally Extensive Transverse Myelitis May Portend a Higher Relapse Rate in Neuromyelitis Optica Spectrum Disorders

G. Orman, K.Y. Wang, Y. Pekcevik, C.B. Thompson, M. Mealy, M. Levy and I. Izbudak
American Journal of Neuroradiology May 2017, 38 (5) 949-953; DOI: https://doi.org/10.3174/ajnr.A5141
G. Orman
aFrom the Division of Neuroradiology (G.O., Y.P., I.I.), Russell H. Morgan Department of Radiology
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K.Y. Wang
cDepartment of Radiology (K.Y.W.), Baylor College of Medicine, Houston, Texas
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Y. Pekcevik
aFrom the Division of Neuroradiology (G.O., Y.P., I.I.), Russell H. Morgan Department of Radiology
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C.B. Thompson
dBiostatistics Center (C.B.T.), Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
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M. Mealy
bDepartment of Neurology (M.M., M.L.), The Johns Hopkins University School of Medicine, Baltimore, Maryland
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M. Levy
bDepartment of Neurology (M.M., M.L.), The Johns Hopkins University School of Medicine, Baltimore, Maryland
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I. Izbudak
aFrom the Division of Neuroradiology (G.O., Y.P., I.I.), Russell H. Morgan Department of Radiology
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Article Information

vol. 38 no. 5 949-953
DOI 
https://doi.org/10.3174/ajnr.A5141
PubMed 
28302609

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received December 22, 2016
  • Accepted after revision January 14, 2017
  • Published online May 15, 2017.

Article Versions

  • Latest version (March 16, 2017 - 06:54).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2017 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org

Author Information

  1. G. Ormana,
  2. K.Y. Wangc,
  3. Y. Pekcevika,
  4. C.B. Thompsond,
  5. M. Mealyb,
  6. M. Levyb and
  7. I. Izbudaka
  1. aFrom the Division of Neuroradiology (G.O., Y.P., I.I.), Russell H. Morgan Department of Radiology
  2. bDepartment of Neurology (M.M., M.L.), The Johns Hopkins University School of Medicine, Baltimore, Maryland
  3. cDepartment of Radiology (K.Y.W.), Baylor College of Medicine, Houston, Texas
  4. dBiostatistics Center (C.B.T.), Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
  1. Please address correspondence to Izlem Izbudak, MD, Division of Neuroradiology, Russell H. Morgan Department of Radiology, The Johns Hopkins University School of Medicine, 600 N Wolfe St, Phipps B-126B, Baltimore, MD 21287; e-mail: iizbuda1{at}jhmi.edu
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Cited By...

  • 8 Citations
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This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Neuromyelitis Optica Spectrum Disorders: Spectrum of MR Imaging Findings and Their Differential Diagnosis
    Bruna Garbugio Dutra, Antônio José da Rocha, Renato Hoffmann Nunes, Antônio Carlos Martins Maia
    RadioGraphics 2018 38 1
  • Risk of relapse in patients with neuromyelitis optica spectrum disorder: Recognition and preventive strategy
    Xiaoyu Ma, Allan G. Kermode, Xueqiang Hu, Wei Qiu
    Multiple Sclerosis and Related Disorders 2020 46
  • Neuromyelitis Optica Spectrum Disorders
    Fiona Costello
    CONTINUUM: Lifelong Learning in Neurology 2022 28 4
  • Differential patterns of interhemispheric functional connectivity between AQP4-optic neuritis and MOG-optic neuritis: a resting-state functional MRI study
    Mingming Sun, Huanfen Zhou, Quangang Xu, Mo Yang, Xintong Xu, Ming Zhou, Shihui Wei
    Acta Radiologica 2021 62 6
  • Combined platelet-to-lymphocyte ratio and blood-brain barrier biomarkers as indicators of disability in acute neuromyelitis optica spectrum disorder
    Hongjing Yan, Yining Wang, Yanmei Li, Xiaoling Shen, Lifen Ma, Min Wang, Juan Du, Weifeng Chen, Xutao Xi, Bin Li
    Neurological Sciences 2024 45 2
  • Brain MRI Findings in Pediatric-Onset Neuromyelitis Optica Spectrum Disorder: Challenges in Differentiation from Acute Disseminated Encephalomyelitis
    E. Bulut, J. Karakaya, S. Salama, M. Levy, T.A.G.M. Huisman, I. Izbudak
    American Journal of Neuroradiology 2019
  • Imaging findings and diagnosis of atypical aggressive demyelinating lesions of the central nervous system
    Matteo PAOLETTI, Shaun I. MUZIC, Francesca MARCHETTI, Carlo ASTEGGIANO, Anna PICHIECCHIO, Stefano BASTIANELLO
    Journal of Radiological Review 2021 8 3
  • A Case-Control Study on the Relationship Between Lesion Burden and Expanded Disability Status Scale in Aquaporin-4-Positive and Aquaporin-4-Negative Neuromyelitis Optica Spectrum Disorder Patients
    Mohamad Ghazanfari Hashemi, Mohammad Ali Sahraian, Abolfazl Akbarzadeh, Alireza Ranjbar Naeini, Hassan Mellatyar, Sina Sattari, Amir Nezami Asl
    Iranian Journal of Radiology 2024 21 4
  • Acute neuromyelitis optica spectrum disorder patients’ clinical analysis of disability-related biomarkers
    Xingyue Zheng, Hongjing Yan, Hao Yin, Jing Shi, Yuanyuan Liu, Haotian Zhao, Yuzhi Li, Huakun Liu, Lei Zhang, Zhongrui Yan, Chunbo Dong
    BMC Neurology 2025 25 1
  • Etiological and clinical characterization of longitudinally extensive spinal cord lesions: A 12-year tertiary center experience
    Miguel Mas-Serrano, Pascual Elvira-Ruiz, Carlos José De-Miguel-Sánchez-de-Puerta, Manuel Comabella-López, Juan Pablo Cuello, María Luísa Martínez-Ginés, José Manuel García-Domínguez
    Multiple Sclerosis and Related Disorders 2025 94
  • Expertddx: Brain and Spine
    Miral D. Jhaveri, Karen L. Salzman, Jeffrey S. Ross, Kevin R. Moore, Anne G. Osborn, Chang Yueh Ho
    2018
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American Journal of Neuroradiology: 38 (5)
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Cite this article
G. Orman, K.Y. Wang, Y. Pekcevik, C.B. Thompson, M. Mealy, M. Levy, I. Izbudak
Enhancing Brain Lesions during Acute Optic Neuritis and/or Longitudinally Extensive Transverse Myelitis May Portend a Higher Relapse Rate in Neuromyelitis Optica Spectrum Disorders
American Journal of Neuroradiology May 2017, 38 (5) 949-953; DOI: 10.3174/ajnr.A5141

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Enhancing Brain Lesions during Acute Optic Neuritis and/or Longitudinally Extensive Transverse Myelitis May Portend a Higher Relapse Rate in Neuromyelitis Optica Spectrum Disorders
G. Orman, K.Y. Wang, Y. Pekcevik, C.B. Thompson, M. Mealy, M. Levy, I. Izbudak
American Journal of Neuroradiology May 2017, 38 (5) 949-953; DOI: 10.3174/ajnr.A5141
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Cited By...

  • Brain MRI Findings in Pediatric-Onset Neuromyelitis Optica Spectrum Disorder: Challenges in Differentiation from Acute Disseminated Encephalomyelitis
  • Crossref (11)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Neuromyelitis Optica Spectrum Disorders: Spectrum of MR Imaging Findings and Their Differential Diagnosis
    Bruna Garbugio Dutra, Antônio José da Rocha, Renato Hoffmann Nunes, Antônio Carlos Martins Maia
    RadioGraphics 2018 38 1
  • Risk of relapse in patients with neuromyelitis optica spectrum disorder: Recognition and preventive strategy
    Xiaoyu Ma, Allan G. Kermode, Xueqiang Hu, Wei Qiu
    Multiple Sclerosis and Related Disorders 2020 46
  • Neuromyelitis Optica Spectrum Disorders
    Fiona Costello
    CONTINUUM: Lifelong Learning in Neurology 2022 28 4
  • Differential patterns of interhemispheric functional connectivity between AQP4-optic neuritis and MOG-optic neuritis: a resting-state functional MRI study
    Mingming Sun, Huanfen Zhou, Quangang Xu, Mo Yang, Xintong Xu, Ming Zhou, Shihui Wei
    Acta Radiologica 2021 62 6
  • Combined platelet-to-lymphocyte ratio and blood-brain barrier biomarkers as indicators of disability in acute neuromyelitis optica spectrum disorder
    Hongjing Yan, Yining Wang, Yanmei Li, Xiaoling Shen, Lifen Ma, Min Wang, Juan Du, Weifeng Chen, Xutao Xi, Bin Li
    Neurological Sciences 2024 45 2
  • Brain MRI Findings in Pediatric-Onset Neuromyelitis Optica Spectrum Disorder: Challenges in Differentiation from Acute Disseminated Encephalomyelitis
    E. Bulut, J. Karakaya, S. Salama, M. Levy, T.A.G.M. Huisman, I. Izbudak
    American Journal of Neuroradiology 2019
  • Imaging findings and diagnosis of atypical aggressive demyelinating lesions of the central nervous system
    Matteo PAOLETTI, Shaun I. MUZIC, Francesca MARCHETTI, Carlo ASTEGGIANO, Anna PICHIECCHIO, Stefano BASTIANELLO
    Journal of Radiological Review 2021 8 3
  • A Case-Control Study on the Relationship Between Lesion Burden and Expanded Disability Status Scale in Aquaporin-4-Positive and Aquaporin-4-Negative Neuromyelitis Optica Spectrum Disorder Patients
    Mohamad Ghazanfari Hashemi, Mohammad Ali Sahraian, Abolfazl Akbarzadeh, Alireza Ranjbar Naeini, Hassan Mellatyar, Sina Sattari, Amir Nezami Asl
    Iranian Journal of Radiology 2024 21 4
  • Acute neuromyelitis optica spectrum disorder patients’ clinical analysis of disability-related biomarkers
    Xingyue Zheng, Hongjing Yan, Hao Yin, Jing Shi, Yuanyuan Liu, Haotian Zhao, Yuzhi Li, Huakun Liu, Lei Zhang, Zhongrui Yan, Chunbo Dong
    BMC Neurology 2025 25 1
  • Etiological and clinical characterization of longitudinally extensive spinal cord lesions: A 12-year tertiary center experience
    Miguel Mas-Serrano, Pascual Elvira-Ruiz, Carlos José De-Miguel-Sánchez-de-Puerta, Manuel Comabella-López, Juan Pablo Cuello, María Luísa Martínez-Ginés, José Manuel García-Domínguez
    Multiple Sclerosis and Related Disorders 2025 94

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