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Research ArticleAdult Brain
Open Access

Systematic Literature Review of Machine Learning Algorithms Using Pretherapy Radiologic Imaging for Glioma Molecular Subtype Prediction

Jan Lost, Tej Verma, Leon Jekel, Marc von Reppert, Niklas Tillmanns, Sara Merkaj, Gabriel Cassinelli Petersen, Ryan Bahar, Ayyüce Gordem, Muhammad A. Haider, Harry Subramanian, Waverly Brim, Ichiro Ikuta, Antonio Omuro, Gian Marco Conte, Bernadette V. Marquez-Nostra, Arman Avesta, Khaled Bousabarah, Ali Nabavizadeh, Anahita Fathi Kazerooni, Sanjay Aneja, Spyridon Bakas, MingDe Lin, Michael Sabel and Mariam Aboian
American Journal of Neuroradiology September 2023, DOI: https://doi.org/10.3174/ajnr.A8000
Jan Lost
aFrom the Department of Radiology and Biomedical Imaging (J.L., T.V., L.J., M.v.R., N.T., S.M., G.C.P., R.B., A.G., M.A.H., H.S., W.B., B.V.M.-N., A.A., M.L., M.A.), Yale School of Medicine, New Haven, Connecticut
bDepartment of Neurosurgery (J.L., M.S.), Heinrich-Heine-University, Duesseldorf, Germany
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Tej Verma
aFrom the Department of Radiology and Biomedical Imaging (J.L., T.V., L.J., M.v.R., N.T., S.M., G.C.P., R.B., A.G., M.A.H., H.S., W.B., B.V.M.-N., A.A., M.L., M.A.), Yale School of Medicine, New Haven, Connecticut
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Leon Jekel
aFrom the Department of Radiology and Biomedical Imaging (J.L., T.V., L.J., M.v.R., N.T., S.M., G.C.P., R.B., A.G., M.A.H., H.S., W.B., B.V.M.-N., A.A., M.L., M.A.), Yale School of Medicine, New Haven, Connecticut
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Marc von Reppert
aFrom the Department of Radiology and Biomedical Imaging (J.L., T.V., L.J., M.v.R., N.T., S.M., G.C.P., R.B., A.G., M.A.H., H.S., W.B., B.V.M.-N., A.A., M.L., M.A.), Yale School of Medicine, New Haven, Connecticut
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Niklas Tillmanns
aFrom the Department of Radiology and Biomedical Imaging (J.L., T.V., L.J., M.v.R., N.T., S.M., G.C.P., R.B., A.G., M.A.H., H.S., W.B., B.V.M.-N., A.A., M.L., M.A.), Yale School of Medicine, New Haven, Connecticut
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  • ORCID record for Niklas Tillmanns
Sara Merkaj
aFrom the Department of Radiology and Biomedical Imaging (J.L., T.V., L.J., M.v.R., N.T., S.M., G.C.P., R.B., A.G., M.A.H., H.S., W.B., B.V.M.-N., A.A., M.L., M.A.), Yale School of Medicine, New Haven, Connecticut
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Gabriel Cassinelli Petersen
aFrom the Department of Radiology and Biomedical Imaging (J.L., T.V., L.J., M.v.R., N.T., S.M., G.C.P., R.B., A.G., M.A.H., H.S., W.B., B.V.M.-N., A.A., M.L., M.A.), Yale School of Medicine, New Haven, Connecticut
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  • ORCID record for Gabriel Cassinelli Petersen
Ryan Bahar
aFrom the Department of Radiology and Biomedical Imaging (J.L., T.V., L.J., M.v.R., N.T., S.M., G.C.P., R.B., A.G., M.A.H., H.S., W.B., B.V.M.-N., A.A., M.L., M.A.), Yale School of Medicine, New Haven, Connecticut
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Ayyüce Gordem
aFrom the Department of Radiology and Biomedical Imaging (J.L., T.V., L.J., M.v.R., N.T., S.M., G.C.P., R.B., A.G., M.A.H., H.S., W.B., B.V.M.-N., A.A., M.L., M.A.), Yale School of Medicine, New Haven, Connecticut
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Muhammad A. Haider
aFrom the Department of Radiology and Biomedical Imaging (J.L., T.V., L.J., M.v.R., N.T., S.M., G.C.P., R.B., A.G., M.A.H., H.S., W.B., B.V.M.-N., A.A., M.L., M.A.), Yale School of Medicine, New Haven, Connecticut
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Harry Subramanian
aFrom the Department of Radiology and Biomedical Imaging (J.L., T.V., L.J., M.v.R., N.T., S.M., G.C.P., R.B., A.G., M.A.H., H.S., W.B., B.V.M.-N., A.A., M.L., M.A.), Yale School of Medicine, New Haven, Connecticut
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Waverly Brim
aFrom the Department of Radiology and Biomedical Imaging (J.L., T.V., L.J., M.v.R., N.T., S.M., G.C.P., R.B., A.G., M.A.H., H.S., W.B., B.V.M.-N., A.A., M.L., M.A.), Yale School of Medicine, New Haven, Connecticut
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Ichiro Ikuta
cDepartment of Radiology (I.I.), Mayo Clinic Arizona, Phoenix, Arizona
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Antonio Omuro
dDepartment of Neurology and Yale Cancer Center (A.O.), Yale School of Medicine, New Haven, Connecticut
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Gian Marco Conte
eDepartment of Radiology (G.M.C.), Mayo Clinic, Rochester, Minesotta
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Bernadette V. Marquez-Nostra
aFrom the Department of Radiology and Biomedical Imaging (J.L., T.V., L.J., M.v.R., N.T., S.M., G.C.P., R.B., A.G., M.A.H., H.S., W.B., B.V.M.-N., A.A., M.L., M.A.), Yale School of Medicine, New Haven, Connecticut
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Arman Avesta
aFrom the Department of Radiology and Biomedical Imaging (J.L., T.V., L.J., M.v.R., N.T., S.M., G.C.P., R.B., A.G., M.A.H., H.S., W.B., B.V.M.-N., A.A., M.L., M.A.), Yale School of Medicine, New Haven, Connecticut
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Khaled Bousabarah
fVisage Imaging Inc (K.B., M.L.), San Diego, California
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Ali Nabavizadeh
gDepartment of Radiology (A.N.), Perelman School of Medicine, Hospital of University of Pennsylvania, University of Pennsylvania, Philadelphia, Pennsylvania
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Anahita Fathi Kazerooni
hDepartment of Neurosurgery (A.F.K.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
iDivision of Neurosurgery (A.F.K.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
jCenter for Data-Driven Discovery (A.F.K.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
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Sanjay Aneja
kDepartment of Therapeutic Radiology (S.A), Yale School of Medicine, New Haven, Connecticut
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Spyridon Bakas
lCenter for Biomedical Image Computing and Analytics (S.B.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
mRichards Medical Research Laboratories (S.B.), Philadelphia, Pennsylvania
nDepartment of Radiology (S.B.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
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MingDe Lin
aFrom the Department of Radiology and Biomedical Imaging (J.L., T.V., L.J., M.v.R., N.T., S.M., G.C.P., R.B., A.G., M.A.H., H.S., W.B., B.V.M.-N., A.A., M.L., M.A.), Yale School of Medicine, New Haven, Connecticut
fVisage Imaging Inc (K.B., M.L.), San Diego, California
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Michael Sabel
bDepartment of Neurosurgery (J.L., M.S.), Heinrich-Heine-University, Duesseldorf, Germany
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Mariam Aboian
aFrom the Department of Radiology and Biomedical Imaging (J.L., T.V., L.J., M.v.R., N.T., S.M., G.C.P., R.B., A.G., M.A.H., H.S., W.B., B.V.M.-N., A.A., M.L., M.A.), Yale School of Medicine, New Haven, Connecticut
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Article Information

DOI 
https://doi.org/10.3174/ajnr.A8000
PubMed 
37770204

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received February 27, 2023
  • Accepted after revision August 1, 2023
  • Published online September 28, 2023.

Article Versions

  • You are currently viewing a Latest version of this article (September 28, 2023 - 12:09).
  • View the most recent version of this article
Copyright & Usage 
© 2023 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org

Author Information

  1. Jan Losta,b,
  2. Tej Vermaa,
  3. Leon Jekela,
  4. Marc von Repperta,
  5. Niklas Tillmannsa,
  6. Sara Merkaja,
  7. Gabriel Cassinelli Petersena,
  8. Ryan Bahara,
  9. Ayyüce Gordema,
  10. Muhammad A. Haidera,
  11. Harry Subramaniana,
  12. Waverly Brima,
  13. Ichiro Ikutac,
  14. Antonio Omurod,
  15. Gian Marco Contee,
  16. Bernadette V. Marquez-Nostraa,
  17. Arman Avestaa,
  18. Khaled Bousabarahf,
  19. Ali Nabavizadehg,
  20. Anahita Fathi Kazeroonih,i,j,
  21. Sanjay Anejak,
  22. Spyridon Bakasl,m,n,
  23. MingDe Lina,f,
  24. Michael Sabelb and
  25. Mariam Aboiana
  1. aFrom the Department of Radiology and Biomedical Imaging (J.L., T.V., L.J., M.v.R., N.T., S.M., G.C.P., R.B., A.G., M.A.H., H.S., W.B., B.V.M.-N., A.A., M.L., M.A.), Yale School of Medicine, New Haven, Connecticut
  2. bDepartment of Neurosurgery (J.L., M.S.), Heinrich-Heine-University, Duesseldorf, Germany
  3. cDepartment of Radiology (I.I.), Mayo Clinic Arizona, Phoenix, Arizona
  4. dDepartment of Neurology and Yale Cancer Center (A.O.), Yale School of Medicine, New Haven, Connecticut
  5. eDepartment of Radiology (G.M.C.), Mayo Clinic, Rochester, Minesotta
  6. fVisage Imaging Inc (K.B., M.L.), San Diego, California
  7. gDepartment of Radiology (A.N.), Perelman School of Medicine, Hospital of University of Pennsylvania, University of Pennsylvania, Philadelphia, Pennsylvania
  8. hDepartment of Neurosurgery (A.F.K.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
  9. iDivision of Neurosurgery (A.F.K.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
  10. jCenter for Data-Driven Discovery (A.F.K.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
  11. kDepartment of Therapeutic Radiology (S.A), Yale School of Medicine, New Haven, Connecticut
  12. lCenter for Biomedical Image Computing and Analytics (S.B.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
  13. mRichards Medical Research Laboratories (S.B.), Philadelphia, Pennsylvania
  14. nDepartment of Radiology (S.B.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
  1. Please address correspondence to Mariam Aboian, MD, Department of Radiology and Biomedical Imaging, Yale School of Medicine, 333 Cedar St, New Haven, CT 06510; e-mail: mariam.aboian{at}yale.edu
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Funding

  • National Center for Advancing Translational Science (NCATS) - KL2

    TR001862
  • UL1

    TR001863

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Jan Lost, Tej Verma, Leon Jekel, Marc von Reppert, Niklas Tillmanns, Sara Merkaj, Gabriel Cassinelli Petersen, Ryan Bahar, Ayyüce Gordem, Muhammad A. Haider, Harry Subramanian, Waverly Brim, Ichiro Ikuta, Antonio Omuro, Gian Marco Conte, Bernadette V. Marquez-Nostra, Arman Avesta, Khaled Bousabarah, Ali Nabavizadeh, Anahita Fathi Kazerooni, Sanjay Aneja, Spyridon Bakas, MingDe Lin, Michael Sabel, Mariam Aboian
Systematic Literature Review of Machine Learning Algorithms Using Pretherapy Radiologic Imaging for Glioma Molecular Subtype Prediction
American Journal of Neuroradiology Sep 2023, DOI: 10.3174/ajnr.A8000

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Systematic Literature Review of Machine Learning Algorithms Using Pretherapy Radiologic Imaging for Glioma Molecular Subtype Prediction
Jan Lost, Tej Verma, Leon Jekel, Marc von Reppert, Niklas Tillmanns, Sara Merkaj, Gabriel Cassinelli Petersen, Ryan Bahar, Ayyüce Gordem, Muhammad A. Haider, Harry Subramanian, Waverly Brim, Ichiro Ikuta, Antonio Omuro, Gian Marco Conte, Bernadette V. Marquez-Nostra, Arman Avesta, Khaled Bousabarah, Ali Nabavizadeh, Anahita Fathi Kazerooni, Sanjay Aneja, Spyridon Bakas, MingDe Lin, Michael Sabel, Mariam Aboian
American Journal of Neuroradiology Sep 2023, DOI: 10.3174/ajnr.A8000
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This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Clustering Functional Magnetic Resonance Imaging Time Series in Glioblastoma Characterization: A Review of the Evolution, Applications, and Potentials
    Matteo De Simone, Giorgio Iaconetta, Giuseppina Palermo, Alessandro Fiorindi, Karl Schaller, Lucio De Maria
    Brain Sciences 2024 14 3
  • Predicting IDH and ATRX mutations in gliomas from radiomic features with machine learning: a systematic review and meta-analysis
    Chor Yiu Chloe Chung, Laura Elin Pigott
    Frontiers in Radiology 2024 4
  • Enhancing clinical decision-making: An externally validated machine learning model for predicting isocitrate dehydrogenase mutation in gliomas using radiomics from presurgical magnetic resonance imaging
    Jan Lost, Nader Ashraf, Leon Jekel, Marc von Reppert, Niklas Tillmanns, Klara Willms, Sara Merkaj, Gabriel Cassinelli Petersen, Arman Avesta, Divya Ramakrishnan, Antonio Omuro, Ali Nabavizadeh, Spyridon Bakas, Khaled Bousabarah, MingDe Lin, Sanjay Aneja, Michael Sabel, Mariam Aboian
    Neuro-Oncology Advances 2024 6 1
  • Performance of Machine Learning Models in Predicting BRAF Alterations Using Imaging Data in Low-Grade Glioma: A Systematic Review and Meta-Analysis
    Shahryar Rajai Firouzabadi, Roozbeh Tavanaei, Ida Mohammadi, Alireza Alikhani, Ali Ansari, Mohammadhosein Akhlaghpasand, Bardia Hajikarimloo, Raymund L. Yong, Konstantinos Margetis
    World Neurosurgery 2025 195

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