Article Figures & Data
Figures
- FIG 1.
Comparison of the probabilistic and manual labels on a similar coronal section of the Montreal Neurological Institute 152 atlas space brain and a subject’s 7T brain. The left NBM is shown in blue, and the right NBM is shown in red.
- FIG 2.
Flow chart describing how the 7T NBM segmentation is used for training the network to segment the NBM on 3T MR imaging.
- FIG 3.
Example of favorable (A, right), average (A, middle), and poor (A, left) performance. Blue is the correct prediction of NBM, red is the overpredicted NBM (false-positive), and yellow is the ground truth label that was not predicted (false-negative). The Dice coefficient of the favorable example (right) was 0.82, the Dice coefficient of the average example (middle) was 0.63, and the Dice coefficient of the poor example (left) was 0.55. B, The Dice coefficient. C, The mean surface distance. D, The centroid distance of DnSeg versus the probabilistic atlas for both healthy subjects and patients with TLE. The healthy subjects included the nonaugmented held-out test data set (n = 6). The patients with TLE were also not augmented and were held out until final analysis (n = 14). Paired t test: single asterisk indicates P < .05; double asterisks, P < .01; triple asterisks, P < .001.
- FIG 4.
Increased accuracy of NBM electrode targeting with DnSeg. The orange electrode was placed in the center of the NBM segmentation generated by the probabilistic atlas. The blue electrode was placed in the center of the segmentation generated by DnSeg. D, Both electrode positions compared with the ground truth segmentation mesh. The ground truth NBM (manually segmented on 7T MR imaging) is shown in red. The outline of the ground truth NBM as well as the lead trajectories can be seen in A, B, and C. The sample DBS planning for this figure was generated using CRAnial Vault Explorer.23
Tables
Data set demographicsa
Healthy subjects, Vanderbilt No. 11 Sex 3 Female Age (yr) 38.3 (SD, 10.9) Healthy subjects, Amsterdam No. 10 Sex 8 Female Age (yr) 25.9 (SD, 5.8) Patients with TLE No. 14 Age (yr) 30.0 (SD, 7.5) Sex 7 Female Disease duration (yr) 11.0 (SD, 11.7) Number lesional 7 ↵a Demographics of both the healthy subject data set and the TLE data set. Data are counts or mean (SD).
