Antiamyloid Therapy and Cerebral Blood Flow Changes on MRI: A Potential Longitudinal Biomarker of Treatment Response?

Andres Ricaurte-Fajardo; Jana Ivanidze; Deborah Zhang; Meem Mahmud; Weiye Yasen; Lisa Ravdin; Silky Pahlajani; Mony de Leon; Anna S. Nordvig; Gloria C. Chiang

doi:10.3174/ajnr.A8654

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Research ArticleNeurodegenerative Disorder Imaging

Antiamyloid Therapy and Cerebral Blood Flow Changes on MRI: A Potential Longitudinal Biomarker of Treatment Response?

Andres Ricaurte-Fajardo, Jana Ivanidze, Deborah Zhang, Meem Mahmud, Weiye Yasen, Lisa Ravdin, Silky Pahlajani, Mony de Leon, Anna S. Nordvig and Gloria C. Chiang

American Journal of Neuroradiology July 2025, 46 (7) 1439-1445; DOI: https://doi.org/10.3174/ajnr.A8654

Andres Ricaurte-Fajardo

aFrom the Department of Radiology (A.R.-F., J.I., S.P., M.d.L., G.C.C.), Brain Health Imaging Institute, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York

bDepartment of Neurology (A.R.-F.), Pontificia Universidad Javeriana, Bogota, Colombia

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Jana Ivanidze

aFrom the Department of Radiology (A.R.-F., J.I., S.P., M.d.L., G.C.C.), Brain Health Imaging Institute, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York

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Deborah Zhang

cDepartment of Neurology (D.Z., M.M., W.Y., L.R., A.S.N.), Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York

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Meem Mahmud

cDepartment of Neurology (D.Z., M.M., W.Y., L.R., A.S.N.), Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York

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Weiye Yasen

cDepartment of Neurology (D.Z., M.M., W.Y., L.R., A.S.N.), Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York

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Lisa Ravdin

cDepartment of Neurology (D.Z., M.M., W.Y., L.R., A.S.N.), Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York

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Silky Pahlajani

aFrom the Department of Radiology (A.R.-F., J.I., S.P., M.d.L., G.C.C.), Brain Health Imaging Institute, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York

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Mony de Leon

aFrom the Department of Radiology (A.R.-F., J.I., S.P., M.d.L., G.C.C.), Brain Health Imaging Institute, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York

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Anna S. Nordvig

cDepartment of Neurology (D.Z., M.M., W.Y., L.R., A.S.N.), Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York

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Gloria C. Chiang

aFrom the Department of Radiology (A.R.-F., J.I., S.P., M.d.L., G.C.C.), Brain Health Imaging Institute, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York

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1 Jul 2025

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Cite this article

Andres Ricaurte-Fajardo, Jana Ivanidze, Deborah Zhang, Meem Mahmud, Weiye Yasen, Lisa Ravdin, Silky Pahlajani, Mony de Leon, Anna S. Nordvig, Gloria C. Chiang

Antiamyloid Therapy and Cerebral Blood Flow Changes on MRI: A Potential Longitudinal Biomarker of Treatment Response?

American Journal of Neuroradiology Jul 2025, 46 (7) 1439-1445; DOI: 10.3174/ajnr.A8654

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Anti-Amyloid Therapy & CBF as a Response Biomarker

Andres Ricaurte-Fajardo, Jana Ivanidze, Deborah Zhang, Meem Mahmud, Weiye Yasen, Lisa Ravdin, Silky Pahlajani, Mony de Leon, Anna S. Nordvig, Gloria C. Chiang

American Journal of Neuroradiology Jul 2025, 46 (7) 1439-1445; DOI: 10.3174/ajnr.A8654

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