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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleNeurodegenerative Disorder Imaging

Antiamyloid Therapy and Cerebral Blood Flow Changes on MRI: A Potential Longitudinal Biomarker of Treatment Response?

Andres Ricaurte-Fajardo, Jana Ivanidze, Deborah Zhang, Meem Mahmud, Weiye Yasen, Lisa Ravdin, Silky Pahlajani, Mony de Leon, Anna S. Nordvig and Gloria C. Chiang
American Journal of Neuroradiology July 2025, 46 (7) 1439-1445; DOI: https://doi.org/10.3174/ajnr.A8654
Andres Ricaurte-Fajardo
aFrom the Department of Radiology (A.R.-F., J.I., S.P., M.d.L., G.C.C.), Brain Health Imaging Institute, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York
bDepartment of Neurology (A.R.-F.), Pontificia Universidad Javeriana, Bogota, Colombia
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Jana Ivanidze
aFrom the Department of Radiology (A.R.-F., J.I., S.P., M.d.L., G.C.C.), Brain Health Imaging Institute, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York
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  • ORCID record for Jana Ivanidze
Deborah Zhang
cDepartment of Neurology (D.Z., M.M., W.Y., L.R., A.S.N.), Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York
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Meem Mahmud
cDepartment of Neurology (D.Z., M.M., W.Y., L.R., A.S.N.), Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York
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Weiye Yasen
cDepartment of Neurology (D.Z., M.M., W.Y., L.R., A.S.N.), Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York
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Lisa Ravdin
cDepartment of Neurology (D.Z., M.M., W.Y., L.R., A.S.N.), Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York
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Silky Pahlajani
aFrom the Department of Radiology (A.R.-F., J.I., S.P., M.d.L., G.C.C.), Brain Health Imaging Institute, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York
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Mony de Leon
aFrom the Department of Radiology (A.R.-F., J.I., S.P., M.d.L., G.C.C.), Brain Health Imaging Institute, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York
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Anna S. Nordvig
cDepartment of Neurology (D.Z., M.M., W.Y., L.R., A.S.N.), Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York
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Gloria C. Chiang
aFrom the Department of Radiology (A.R.-F., J.I., S.P., M.d.L., G.C.C.), Brain Health Imaging Institute, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York
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Article Information

vol. 46 no. 7 1439-1445
DOI 
https://doi.org/10.3174/ajnr.A8654
PubMed 
39805666

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received November 6, 2024
  • Accepted after revision December 30, 2024
  • Published online July 1, 2025.

Article Versions

  • Latest version (January 13, 2025 - 06:50).
  • Latest version (June 12, 2025 - 09:22).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2025 by American Journal of Neuroradiology

Author Information

  1. Andres Ricaurte-Fajardoa,b,
  2. Jana Ivanidzea,
  3. Deborah Zhangc,
  4. Meem Mahmudc,
  5. Weiye Yasenc,
  6. Lisa Ravdinc,
  7. Silky Pahlajania,
  8. Mony de Leona,
  9. Anna S. Nordvigc and
  10. Gloria C. Chianga
  1. aFrom the Department of Radiology (A.R.-F., J.I., S.P., M.d.L., G.C.C.), Brain Health Imaging Institute, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York
  2. bDepartment of Neurology (A.R.-F.), Pontificia Universidad Javeriana, Bogota, Colombia
  3. cDepartment of Neurology (D.Z., M.M., W.Y., L.R., A.S.N.), Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York
  1. Please address correspondence to Gloria C. Chiang, MD, Department of Radiology, Division of Neuroradiology, Weill Cornell Medicine, NY Presbyterian Hospital, 525 East 68th St, Starr Pavilion, Box 141, New York, NY 10065; e-mail: gcc9004{at}med.cornell.edu; @GloriaChiangMD; @WCMRadiology
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Funding

  • Feil II Clinical Scholar Award

  • National Institute on Aging

    R01 AG085972; R01AG068398; R01AG080011; R56 AG058913; RF1 AG057570
  • Sonia Jaye and Edward Barsukov Foundation

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American Journal of Neuroradiology: 46 (7)
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Vol. 46, Issue 7
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Cite this article
Andres Ricaurte-Fajardo, Jana Ivanidze, Deborah Zhang, Meem Mahmud, Weiye Yasen, Lisa Ravdin, Silky Pahlajani, Mony de Leon, Anna S. Nordvig, Gloria C. Chiang
Antiamyloid Therapy and Cerebral Blood Flow Changes on MRI: A Potential Longitudinal Biomarker of Treatment Response?
American Journal of Neuroradiology Jul 2025, 46 (7) 1439-1445; DOI: 10.3174/ajnr.A8654

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Anti-Amyloid Therapy & CBF as a Response Biomarker
Andres Ricaurte-Fajardo, Jana Ivanidze, Deborah Zhang, Meem Mahmud, Weiye Yasen, Lisa Ravdin, Silky Pahlajani, Mony de Leon, Anna S. Nordvig, Gloria C. Chiang
American Journal of Neuroradiology Jul 2025, 46 (7) 1439-1445; DOI: 10.3174/ajnr.A8654
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