Performance of Standardized Relative CBV for Quantifying Regional Histologic Tumor Burden in Recurrent High-Grade Glioma: Comparison against Normalized Relative CBV Using Image-Localized Stereotactic Biopsies

J.M. Hoxworth; J.M. Eschbacher; A.C. Gonzales; K.W. Singleton; G.D. Leon; K.A. Smith; A.M. Stokes; Y. Zhou; G.L. Mazza; A.B. Porter; M.M. Mrugala; R.S. Zimmerman; B.R. Bendok; D.P. Patra; C. Krishna; J.L. Boxerman; L.C. Baxter; K.R. Swanson; C.C. Quarles; K.M. Schmainda; L.S. Hu

doi:10.3174/ajnr.A6486

Research ArticleAdult Brain

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Performance of Standardized Relative CBV for Quantifying Regional Histologic Tumor Burden in Recurrent High-Grade Glioma: Comparison against Normalized Relative CBV Using Image-Localized Stereotactic Biopsies

J.M. Hoxworth, J.M. Eschbacher, A.C. Gonzales, K.W. Singleton, G.D. Leon, K.A. Smith, A.M. Stokes, Y. Zhou, G.L. Mazza, A.B. Porter, M.M. Mrugala, R.S. Zimmerman, B.R. Bendok, D.P. Patra, C. Krishna, J.L. Boxerman, L.C. Baxter, K.R. Swanson, C.C. Quarles, K.M. Schmainda and L.S. Hu

American Journal of Neuroradiology March 2020, 41 (3) 408-415; DOI: https://doi.org/10.3174/ajnr.A6486

J.M. Hoxworth

aFrom the Departments of Radiology (J.M.H., Y.Z., L.S.H.)

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J.M. Eschbacher

fDepartments of Pathology (J.M.E.)

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A.C. Gonzales

bPsychiatry and Psychology (A.C.G.)

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K.W. Singleton

ePrecision Neurotherapeutics Lab (K.W.S., G.D.L., B.R.B., K.R.S.), Mayo Clinic in Arizona, Phoenix, Arizona

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G.D. Leon

ePrecision Neurotherapeutics Lab (K.W.S., G.D.L., B.R.B., K.R.S.), Mayo Clinic in Arizona, Phoenix, Arizona

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K.A. Smith

iKeller Center for Imaging Innovation (A.M.S.), Barrow Neurological Institute, Phoenix, Arizona

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A.M. Stokes

iKeller Center for Imaging Innovation (A.M.S.), Barrow Neurological Institute, Phoenix, Arizona

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Y. Zhou

aFrom the Departments of Radiology (J.M.H., Y.Z., L.S.H.)

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G.L. Mazza

jDepartment of Health Sciences Research (G.L.M.), Division of Biomedical Statistics and Informatics, Mayo Clinic Scottsdale, Scottsdale, Arizona

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A.B. Porter

cNeuro-Oncology (A.B.P., M.M.M.)

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M.M. Mrugala

cNeuro-Oncology (A.B.P., M.M.M.)

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R.S. Zimmerman

dNeurosurgery (R.S.Z., C.K.)

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B.R. Bendok

ePrecision Neurotherapeutics Lab (K.W.S., G.D.L., B.R.B., K.R.S.), Mayo Clinic in Arizona, Phoenix, Arizona

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D.P. Patra

kDepartments of Neurosurgery (D.P.P.)

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C. Krishna

dNeurosurgery (R.S.Z., C.K.)

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J.L. Boxerman

mDepartment of Diagnostic Imaging (J.L.B.), Rhode Island Hospital, Providence, Rhode Island

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L.C. Baxter

lNeuropsychology (L.C.B.), Mayo Clinic Hospital, Phoenix, Arizona

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K.R. Swanson

ePrecision Neurotherapeutics Lab (K.W.S., G.D.L., B.R.B., K.R.S.), Mayo Clinic in Arizona, Phoenix, Arizona

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C.C. Quarles

hNeurobiology (C.C.Q.)

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K.M. Schmainda

nDepartment of Radiology (K.M.S.), Medical College of Wisconsin, Milwaukee, Wisconsin.

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L.S. Hu

aFrom the Departments of Radiology (J.M.H., Y.Z., L.S.H.)

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Performance of Standardized Relative CBV for Quantifying Regional Histologic Tumor Burden in Recurrent High-Grade Glioma: Comparison against Normalized Relative CBV Using Image-Localized Stereotactic Biopsies

American Journal of Neuroradiology Mar 2020, 41 (3) 408-415; DOI: 10.3174/ajnr.A6486

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American Journal of Neuroradiology Mar 2020, 41 (3) 408-415; DOI: 10.3174/ajnr.A6486

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Performance of Standardized Relative CBV for Quantifying Regional Histologic Tumor Burden in Recurrent High-Grade Glioma: Comparison against Normalized Relative CBV Using Image-Localized Stereotactic Biopsies

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