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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleClinical Report

Intra-Arterial Verapamil Treatment in Oral Therapy–Refractory Reversible Cerebral Vasoconstriction Syndrome

J.M. Ospel, C.H. Wright, R. Jung, L.L.M. Vidal, S. Manjila, G. Singh, D.V. Heck, A. Ray and K.A. Blackham
American Journal of Neuroradiology February 2020, 41 (2) 293-299; DOI: https://doi.org/10.3174/ajnr.A6378
J.M. Ospel
aFrom the Department of Radiology (J.M.O., K.A.B.), Section of Neuroradiology and Interventional Neuroradiology, Basel University Hospital, University of Basel, Basel, Switzerland
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C.H. Wright
bDepartments of Neurological Surgery (C.H.W.)
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R. Jung
eDepartment of Neurology (R.J.), The Sandra and Malcolm Berman Brain & Spine Institute, Sinai Hospital of Baltimore, LIfebridge Health, Baltimore, Maryland
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L.L.M. Vidal
dDepartment of Diagnostic Radiology and Nuclear Medicine (L.L.M.V.), University of Maryland Medical Center, Baltimore, Maryland
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S. Manjila
fDepartment of Neurosurgery and Neurosciences (S.M.), McLaren Bay Region Hospital, Bay City, Michigan
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G. Singh
gDepartment of Radiology (G.S.), Section of Neuroradiology, Newark Beth Israel Medical Center, Newark, New Jersey
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D.V. Heck
hForsyth Radiological Associates (D.V.H.), Winston-Salem, North Carolina.
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A. Ray
cNeurosurgery (A.R.), University Hospitals of Cleveland Case Medical Center, Cleveland, Ohio
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K.A. Blackham
aFrom the Department of Radiology (J.M.O., K.A.B.), Section of Neuroradiology and Interventional Neuroradiology, Basel University Hospital, University of Basel, Basel, Switzerland
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Article Information

vol. 41 no. 2 293-299
DOI 
https://doi.org/10.3174/ajnr.A6378
PubMed 
31879333

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received December 31, 2018
  • Accepted after revision November 16, 2019
  • Published online February 12, 2020.

Article Versions

  • Latest version (December 26, 2019 - 08:11).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2020 by American Journal of Neuroradiology

Author Information

  1. J.M. Ospela,
  2. C.H. Wrightb,
  3. R. Junge,
  4. L.L.M. Vidald,
  5. S. Manjilaf,
  6. G. Singhg,
  7. D.V. Heckh,
  8. A. Rayc and
  9. K.A. Blackhama
  1. aFrom the Department of Radiology (J.M.O., K.A.B.), Section of Neuroradiology and Interventional Neuroradiology, Basel University Hospital, University of Basel, Basel, Switzerland
  2. bDepartments of Neurological Surgery (C.H.W.)
  3. cNeurosurgery (A.R.), University Hospitals of Cleveland Case Medical Center, Cleveland, Ohio
  4. dDepartment of Diagnostic Radiology and Nuclear Medicine (L.L.M.V.), University of Maryland Medical Center, Baltimore, Maryland
  5. eDepartment of Neurology (R.J.), The Sandra and Malcolm Berman Brain & Spine Institute, Sinai Hospital of Baltimore, LIfebridge Health, Baltimore, Maryland
  6. fDepartment of Neurosurgery and Neurosciences (S.M.), McLaren Bay Region Hospital, Bay City, Michigan
  7. gDepartment of Radiology (G.S.), Section of Neuroradiology, Newark Beth Israel Medical Center, Newark, New Jersey
  8. hForsyth Radiological Associates (D.V.H.), Winston-Salem, North Carolina.
  1. Please address correspondence to Johanna Maria Ospel, MD, Department of Radiology, Basel University Hospital, University of Basel, Petersgraben 4, 4051 Basel, Basel, Switzerland; e-mail: johannamaria.ospel{at}usb.ch; @johanna_ospel; @KBlackhamMD
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  • Reversible cerebral vasoconstriction syndrome: literature review
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    The Egyptian Journal of Neurology, Psychiatry and Neurosurgery 2023 59 1
  • Quantifying Intra-Arterial Verapamil Response as a Diagnostic Tool for Reversible Cerebral Vasoconstriction Syndrome
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    Journal of Clinical Neuroscience 2023 113
  • Pediatric Tacrolimus-Induced Reversible Cerebral Vasoconstriction Syndrome after Heart Transplantation
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Cite this article
J.M. Ospel, C.H. Wright, R. Jung, L.L.M. Vidal, S. Manjila, G. Singh, D.V. Heck, A. Ray, K.A. Blackham
Intra-Arterial Verapamil Treatment in Oral Therapy–Refractory Reversible Cerebral Vasoconstriction Syndrome
American Journal of Neuroradiology Feb 2020, 41 (2) 293-299; DOI: 10.3174/ajnr.A6378

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Intra-Arterial Verapamil Treatment in Oral Therapy–Refractory Reversible Cerebral Vasoconstriction Syndrome
J.M. Ospel, C.H. Wright, R. Jung, L.L.M. Vidal, S. Manjila, G. Singh, D.V. Heck, A. Ray, K.A. Blackham
American Journal of Neuroradiology Feb 2020, 41 (2) 293-299; DOI: 10.3174/ajnr.A6378
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Cited By...

  • Quantifying Intra-Arterial Verapamil Response as a Diagnostic Tool for Reversible Cerebral Vasoconstriction Syndrome
  • Crossref (9)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Reversible cerebral vasoconstriction syndrome: review of neuroimaging findings
    Teresa Perillo, Chiara Paolella, Giulia Perrotta, Antonietta Serino, Ferdinando Caranci, Andrea Manto
    La radiologia medica 2022 127 9
  • Reversible cerebral vasoconstriction syndrome: literature review
    Michelle Zonkowski Ribas, Gabriela Ferreira Paticcié, Sara Diógenes Peixoto de Medeiros, Arthur de Oliveira Veras, Felipe Micelli Noleto, Júlio César Claudino dos Santos
    The Egyptian Journal of Neurology, Psychiatry and Neurosurgery 2023 59 1
  • Quantifying Intra-Arterial Verapamil Response as a Diagnostic Tool for Reversible Cerebral Vasoconstriction Syndrome
    J.M. Sequeiros, J.A. Roa, R.P. Sabotin, S. Dandapat, S. Ortega-Gutierrez, E.C. Leira, C.P. Derdeyn, G. Bathla, D.M. Hasan, E.A. Samaniego
    American Journal of Neuroradiology 2020 41 10
  • Verapamil in the treatment of reversible cerebral vasoconstriction syndrome: A systematic review
    Luke Collins, Lydia Lam, Oliver Kleinig, William Proudman, Ruyi Zhang, Michelle Bagster, Joshua Kovoor, Aashray Gupta, Rudy Goh, Stephen Bacchi, David Schultz, Timothy Kleinig
    Journal of Clinical Neuroscience 2023 113
  • Pediatric Tacrolimus-Induced Reversible Cerebral Vasoconstriction Syndrome after Heart Transplantation
    Leah Shabo, Mariam Ishaque, Danyas Sarathy, Jeyan Kumar, Kathryn Xixis, Min Park
    Journal of Pediatric Neurology 2023 21 05
  • Reversible cerebral vasoconstriction syndrome: A review
    A. Kulesh Aleksey, Dmitry A. Demin, Natalia L. Starikova, Sergey A. Mekhryakov, Nadezhda A. Kayleva
    Consilium Medicum 2025 27 02
  • Continuous Intra-arterial Infusion of Verapamil for Severe Vasospasm Treatment After Subarachnoid Hemorrhage: A Case Report
    Debora Lopes, Bárbara Teixeira, Valter Rocha, Miguel G Santos, Elisabete Monteiro
    Cureus 2025
  • Management and Long-Term Outcomes of Patients With Recurrent Stroke-Like Episodes After Cranial Radiotherapy
    Bryan J. Neth, Daniel H. Lachance, Joon H. Uhm, Michael W. Ruff
    The Neurologist 2023 28 4
  • Nimodipine-refractory reversible cerebral vasoconstriction syndrome treated effectively with verapamil
    So Young Park, Joon Ho Lee, In Ja Shin, Raul G. Nogueira, Jin Soo Lee
    Precision and Future Medicine 2020 4 4

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