NAA is a Marker of Disability in Secondary-Progressive MS: A Proton MR Spectroscopic Imaging Study

B.S. Solanky; N.A. John; F. DeAngelis; J. Stutters; F. Prados; T. Schneider; R.A. Parker; C.J. Weir; A. Monteverdi; D. Plantone; A. Doshi; D. MacManus; I. Marshall; F. Barkhof; C.A.M. Gandini Wheeler-Kingshott; J. Chataway; for the MS-SMART Investigators

doi:10.3174/ajnr.A6809

Research ArticleAdult Brain

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NAA is a Marker of Disability in Secondary-Progressive MS: A Proton MR Spectroscopic Imaging Study

B.S. Solanky, N.A. John, F. DeAngelis, J. Stutters, F. Prados, T. Schneider, R.A. Parker, C.J. Weir, A. Monteverdi, D. Plantone, A. Doshi, D. MacManus, I. Marshall, F. Barkhof, C.A.M. Gandini Wheeler-Kingshott, J. Chataway and for the MS-SMART Investigators

American Journal of Neuroradiology December 2020, 41 (12) 2209-2218; DOI: https://doi.org/10.3174/ajnr.A6809

B.S. Solanky

aFrom the Department of Neuroinflammation (B.S.S., N.A.J., F.D., J.S., F.P., D.P., A.D., D.M., C.A.M.G.W.-K., J.C.), Faculty of Brain Sciences, Queen Square Multiple Sclerosis Centre, UCL Queen Square Institute of Neurology

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N.A. John

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F. DeAngelis

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J. Stutters

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F. Prados

bCentre for Medical Image Computing (F.P., F.B.), Department of Medical Physics and Biomedical Engineering, University College London, London, UK

jUniversitat Oberta de Catalunya (F.P.), Barcelona, Spain

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T. Schneider

iPhilips UK (T.S.), Guildford, Surrey, UK

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R.A. Parker

cEdinburgh Clinical Trials Unit (R.A.P., C.J.W.), Usher Institute

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C.J. Weir

cEdinburgh Clinical Trials Unit (R.A.P., C.J.W.), Usher Institute

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A. Monteverdi

fDepartment of Brain and Behavioural Sciences (A.M., C.A.M.G.W.-K.), University of Pavia, Pavia, Italy

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D. Plantone

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A. Doshi

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D. MacManus

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I. Marshall

dCentre for Clinical Brain Sciences (I.M.), University of Edinburgh, Edinburgh, UK.

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F. Barkhof

bCentre for Medical Image Computing (F.P., F.B.), Department of Medical Physics and Biomedical Engineering, University College London, London, UK

gNational Institute for Health Research (F.B.), University College London Hospitals Biomedical Research Centre, London, UK

hDepartment of Radiology and Nuclear Medicine (F.B., J.C.), MS Center Amsterdam, Amsterdam, the Netherlands

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C.A.M. Gandini Wheeler-Kingshott

eBrain MRI 3T Research Center (C.A.M.G.W.-K.), Scientific Institute for Research, Hospitalization and Healthcare Mondino National Neurological Institute Foundation, Pavia, Italy

fDepartment of Brain and Behavioural Sciences (A.M., C.A.M.G.W.-K.), University of Pavia, Pavia, Italy

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J. Chataway

hDepartment of Radiology and Nuclear Medicine (F.B., J.C.), MS Center Amsterdam, Amsterdam, the Netherlands

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NAA is a Marker of Disability in Secondary-Progressive MS: A Proton MR Spectroscopic Imaging Study

American Journal of Neuroradiology Dec 2020, 41 (12) 2209-2218; DOI: 10.3174/ajnr.A6809

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NAA is a Marker of Disability in Secondary-Progressive MS: A Proton MR Spectroscopic Imaging Study

American Journal of Neuroradiology Dec 2020, 41 (12) 2209-2218; DOI: 10.3174/ajnr.A6809

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