Table of Contents
Editorials
Perspectives
Editorials
Review Articles
Research Perspectives
Commentary
Functional Vignette
Brain
- Evaluation of Virtual Noncontrast Images Obtained from Dual-Energy CTA for Diagnosing Subarachnoid Hemorrhage
A group of 37 patients underwent noncontrast CT and dual-energy CTA for diagnosis of SAH. From the latter, virtual noncontrast images were reconstructed and assessed for SAH. Agreement between true and virtual noncontrast images for diagnosis of SAH was 92%. Thus, virtual noncontrast CT images reliably diagnosed SAH while reducing radiation dose. (See accompanying commentary by Brisman.)
Commentary
- Neurovascular Manifestations in Hereditary Hemorrhagic Telangiectasia: Imaging Features and Genotype-Phenotype Correlations
Imaging features were correlated with genotypes in 75 patients with hereditary hemorrhagic telangiectasia. Sixty-one percent of patients showed small, superficial, capillary malformations without shunting, whereas 43% had true AVMs of small size and low Spetzler-Martin grade. High-flow AVFs were present in 12% of patients and multiple malformations were seen in 44%. No correlation between gene mutations and lesion types was found.
- Diffusion and Perfusion MRI to Differentiate Treatment-Related Changes Including Pseudoprogression from Recurrent Tumors in High-Grade Gliomas with Histopathologic Evidence
Sixty-eight patients with treated high-grade gliomas who developed increasing enhancing masses of indeterminate nature underwent DWI and DSC as part of their studies. Pseudoprogression was found in 15% who showed higher ADC as well as lower relative cerebral blood volume when compared with those with recurrent tumors.
- Increased Number of White Matter Lesions in Patients with Familial Cerebral Cavernous Malformations
Because endothelial cell abnormalities are found in white matter hyperintensities and cavernous malformations, the authors set out to determine if an increased number of white matter lesions was present in 191 patients with familial cerebral cavernous malformations all carrying the same gene defect. Results were compared with those obtained via logistic regression analysis in healthy controls and patients with sporadic cavernous malformations. White matter lesions were found in 15% of patients with the familial disease, 2% of healthy controls, and 2.5% of those with sporadic malformations. In patients with the familial disease, only age was associated with white matter lesions.
Interventional
Commentary
Head & Neck
Spine
- Incidence of Inadvertent Intravascular Injection during CT Fluoroscopy–Guided Epidural Steroid Injections
Retrospective analysis of 575 CT fluoroscopy-guided epidural injections was done to detect inadvertent arterial or venous injections. Intravascular injections occurred in 26% of cervical transforaminal injections, 9% of cervical interlaminar injections, 8% of lumbar transforaminal injections, and 2% of lumbar interlaminar injections. These findings are similar to previous reports using conventional fluoroscopy and demonstrate that intravascular injections may be detected with CT fluoroscopy.
- Validation of Multisociety Combined Task Force Definitions of Abnormal Disk Morphology
Fifty-four patients underwent classification of lumbar disk herniations during preoperative MRI and surgery using the new multisociety classification. Disagreement as to classification based on MRI studies occurred in only 1 instance and agreement of preoperative classification with operative findings was 70%. The authors believe that though this level of agreement is reasonable, differences exist between what neuroradiologists see on imaging and what surgeons encounter.
