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Research ArticleADULT BRAIN

Ultra-High-Field MRI Visualization of Cortical Multiple Sclerosis Lesions with T2 and T2*: A Postmortem MRI and Histopathology Study

L.E. Jonkman, R. Klaver, L. Fleysher, M. Inglese and J.J.G. Geurts
American Journal of Neuroradiology November 2015, 36 (11) 2062-2067; DOI: https://doi.org/10.3174/ajnr.A4418
L.E. Jonkman
aFrom the Department of Anatomy and Neurosciences (L.E.J., R.K., J.J.G.G.), VU University Medical Center, Amsterdam, the Netherlands
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R. Klaver
aFrom the Department of Anatomy and Neurosciences (L.E.J., R.K., J.J.G.G.), VU University Medical Center, Amsterdam, the Netherlands
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L. Fleysher
bDepartments of Radiology (L.F., M.I.)
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M. Inglese
bDepartments of Radiology (L.F., M.I.)
cNeurology (M.I.)
dNeurosciences (M.I.), Mount Sinai School of Medicine, New York, New York
eDepartments of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (M.I.), University of Genoa, Genoa, Italy.
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J.J.G. Geurts
aFrom the Department of Anatomy and Neurosciences (L.E.J., R.K., J.J.G.G.), VU University Medical Center, Amsterdam, the Netherlands
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Article Information

vol. 36 no. 11 2062-2067
DOI 
https://doi.org/10.3174/ajnr.A4418
PubMed 
26228878

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received February 23, 2015
  • Accepted after revision April 2, 2015
  • Published online November 13, 2015.

Article Versions

  • Latest version (July 30, 2015 - 06:50).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2015 by American Journal of Neuroradiology

Author Information

  1. L.E. Jonkmana,
  2. R. Klavera,
  3. L. Fleysherb,
  4. M. Ingleseb,c,d,e and
  5. J.J.G. Geurtsa
  1. aFrom the Department of Anatomy and Neurosciences (L.E.J., R.K., J.J.G.G.), VU University Medical Center, Amsterdam, the Netherlands
  2. bDepartments of Radiology (L.F., M.I.)
  3. cNeurology (M.I.)
  4. dNeurosciences (M.I.), Mount Sinai School of Medicine, New York, New York
  5. eDepartments of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (M.I.), University of Genoa, Genoa, Italy.
  1. Please address correspondence to L.E. Jonkman, VU University Medical Center, Department of Anatomy and Neurosciences, van der Boechorststraat 7, 1081 BT Amsterdam, the Netherlands; e-mail: le.jonkman{at}vumc.nl
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American Journal of Neuroradiology: 36 (11)
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Cite this article
L.E. Jonkman, R. Klaver, L. Fleysher, M. Inglese, J.J.G. Geurts
Ultra-High-Field MRI Visualization of Cortical Multiple Sclerosis Lesions with T2 and T2*: A Postmortem MRI and Histopathology Study
American Journal of Neuroradiology Nov 2015, 36 (11) 2062-2067; DOI: 10.3174/ajnr.A4418

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Ultra-High-Field MRI Visualization of Cortical Multiple Sclerosis Lesions with T2 and T2*: A Postmortem MRI and Histopathology Study
L.E. Jonkman, R. Klaver, L. Fleysher, M. Inglese, J.J.G. Geurts
American Journal of Neuroradiology Nov 2015, 36 (11) 2062-2067; DOI: 10.3174/ajnr.A4418
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Cited By...

  • Imaging cortical multiple sclerosis lesions with ultra-high field MRI
  • Comparison of Multiple Sclerosis Cortical Lesion Types Detected by Multicontrast 3T and 7T MRI
  • Improved Visualization of Cortical Lesions in Multiple Sclerosis Using 7T MP2RAGE
  • Crossref (25)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Deep Learning Based Noise Reduction for Brain MR Imaging: Tests on Phantoms and Healthy Volunteers
    Masafumi Kidoh, Kensuke Shinoda, Mika Kitajima, Kenzo Isogawa, Masahito Nambu, Hiroyuki Uetani, Kosuke Morita, Takeshi Nakaura, Machiko Tateishi, Yuichi Yamashita, Yasuyuki Yamashita
    Magnetic Resonance in Medical Sciences 2020 19 3
  • Iron in Multiple Sclerosis and Its Noninvasive Imaging with Quantitative Susceptibility Mapping
    Carsten Stüber, David Pitt, Yi Wang
    International Journal of Molecular Sciences 2016 17 1
  • Improved Visualization of Cortical Lesions in Multiple Sclerosis Using 7T MP2RAGE
    E.S. Beck, P. Sati, V. Sethi, T. Kober, B. Dewey, P. Bhargava, G. Nair, I.C. Cortese, D.S. Reich
    American Journal of Neuroradiology 2018 39 3
  • Comparison of Multiple Sclerosis Cortical Lesion Types Detected by Multicontrast 3T and 7T MRI
    J. Maranzano, M. Dadar, D.A. Rudko, D. De Nigris, C. Elliott, J.S. Gati, S.A. Morrow, R.S. Menon, D.L. Collins, D.L. Arnold, S. Narayanan
    American Journal of Neuroradiology 2019 40 7
  • Iron related changes in MS lesions and their validity to characterize MS lesion types and dynamics with Ultra‐high field magnetic resonance imaging
    Simon Hametner, Assunta Dal Bianco, Siegfried Trattnig, Hans Lassmann
    Brain Pathology 2018 28 5
  • Present and future of the diagnostic work-up of multiple sclerosis: the imaging perspective
    Massimo Filippi, Paolo Preziosa, Douglas L. Arnold, Frederik Barkhof, Daniel M. Harrison, Pietro Maggi, Caterina Mainero, Xavier Montalban, Elia Sechi, Brian G. Weinshenker, Maria A. Rocca
    Journal of Neurology 2023 270 3
  • The substrate of increased cortical FA in MS: A 7T post-mortem MRI and histopathology study
    Laura E Jonkman, Roel Klaver, Lazar Fleysher, Matilde Inglese, Jeroen JG Geurts
    Multiple Sclerosis Journal 2016 22 14
  • Clinical Neuroimaging Using 7 T MRI: Challenges and Prospects
    Maria Isabel Vargas, Pascal Martelli, Lijing Xin, Ozlem Ipek, Frederic Grouiller, Francesca Pittau, Robert Trampel, Rolf Gruetter, Serge Vulliemoz, Francois Lazeyras
    Journal of Neuroimaging 2018 28 1
  • Imaging cortical multiple sclerosis lesions with ultra-high field MRI
    Mads A.J. Madsen, Vanessa Wiggermann, Stephan Bramow, Jeppe Romme Christensen, Finn Sellebjerg, Hartwig R. Siebner
    NeuroImage: Clinical 2021 32
  • Ultra-high field MTR and qR2* differentiates subpial cortical lesions from normal-appearing gray matter in multiple sclerosis
    Laura E Jonkman, Lazar Fleysher, Martijn D Steenwijk, Jan A Koeleman, Teun-Pieter de Snoo, Frederik Barkhof, Matilde Inglese, Jeroen JG Geurts
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