Open access

107 Adding space to TiME by sequential immunofluorescence: a new dimension for the spatial biomarkers painting in a clinical cohort of lymphoma case
Pedro Machado Almeida, Albertr Santamaria-Martínez, Emilie Peres, Elisa Oricchio, Diego Dupouy, Marco Cassano

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A121; DOI: 10.1136/jitc-2023-SITC2023.0107
108 Unveiling the diversity in melanoma immunotherapy response biomarkers between lymph node and non-lymph node biopsies
Ettai Markovits, Nethanel Asher, Guy Ben-Betzalel, Assaf Debby, Becky Arbiv, Ron Elran, Yuval Shachaf, Shai Bookstein, Lena Tsabari, Pinchas Birnbaum, Tal Dankovich, Amit Bart, Yoad Cohen, Kenneth Bloom, Oscar Puig, Ronnie Shapira-Frommer, Iris Barshack

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A122-A124; DOI: 10.1136/jitc-2023-SITC2023.0108
109 Automated detection of human papilloma virus (HPV) mRNA using RNAscope technology on the ONCORE ProX
Julio Masabanda, Joseph Vargas, Christopher Edelenbos, Jason Ramos

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A125; DOI: 10.1136/jitc-2023-SITC2023.0109
110 Deep learning models identify key tumor microenvironment features associated with genetic signatures of UV mutagenesis and alkylating agent treatment in melanoma
Shima Nofallah, Darpan T Sanghavi, Sidharth Gupta, Ciyue Shen, Nhat Le, Limin Yu, Bahar Rahsepar, Ryan Leung, Benjamin Glass, Amaro Taylor-Weiner, Ylaine Gerardin, John Abel, Jake Conway

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A126; DOI: 10.1136/jitc-2023-SITC2023.0110
111 Spatial characterization of the tumor microenvironment with cell DIVE multiplexed imaging and HALO quantitative image analysis
Amber L Ortiz, Michael Smith, Lisa Arvidson, Ines Nearchou, Douglas Bowman, Arindam Bose

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A127; DOI: 10.1136/jitc-2023-SITC2023.0111
113 A single-cell spatially resolved atlas of immune-mediated control of lung adenocarcinoma
Tito Panciera, Francesca Zanconato, Michelangelo Cordenonsi, Mattia Forcato, Giada Vanni, Silvio Bicciato, Julian Preciado, Saskia Ilcisin, Katrina Raay, Margaret Hoang, Michael Patrick, Shanshan He, Joseph Beechem, Stefano Piccolo

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A128; DOI: 10.1136/jitc-2023-SITC2023.0113
114 SignalStar™ is a novel multiplex IHC technology that demonstrates flexibility and reproducibility
Derek Papalegis, Sasha Tkachev, Lily Vu, Sarah Klein

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A129; DOI: 10.1136/jitc-2023-SITC2023.0114
115 Comprehensive spatial, transcriptomic, and genomic analysis of immunogenic biliary tract cancer
Wungki Park, Fergus Keane, Hulya Sahin Ozkan, Allison Richards, Vasilisa Rudneva, Danny Khalil, Kevin Soares, Bruno A Costa, Darren Cowzer, Zeyneb Tarcan, James Harding, Olca Basturk, Dae Won Kim, William Jarnagin, Ghassan Abou-Alfa, Mark Donoghue, Eileen M O’Reilly

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A130-A131; DOI: 10.1136/jitc-2023-SITC2023.0115
116 Multiplex immunofluorescence panels, multi-spectral imaging and AI-driven analysis – powerful tools for prostate cancer research and immunotherapy
Sharwari J Phanse, Patrick J Savickas, Rachel Clary, Andrzej Cholewinski

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A132; DOI: 10.1136/jitc-2023-SITC2023.0116
117 Ultrahigh-plex to high-throughput spatial phenotyping: an integrated pathway from discovery to translational and clinical studies
Aditya Pratapa, Ning Ma, Lorcan Sherry, Matthew MacFarlane, Gabriel Reines March, Niyati Jhaveri, Najiba Mammadova

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A133; DOI: 10.1136/jitc-2023-SITC2023.0117

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