Open access

118 Multimodal stratification of predictive biomarkers in head and neck cancers: a focus on cytokine-based immunotherapy
Corinne Ramos, Richard Ruez, Sandra Delebecq, Victor Senechal

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A134; DOI: 10.1136/jitc-2023-SITC2023.0118
119 Uncovering spatial biology of mouse tumor immune microenvironment using imaging mass cytometry
Qanber Raza, Liang Lim, Thomas D Pfister, Christina Loh

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A135; DOI: 10.1136/jitc-2023-SITC2023.0119
120 Human immuno-oncology proteome atlas enables a holistic proteomic approach for spatial biology discovery in FFPE tissues
Alyssa Rosenbloom, Shilah Bonnett, Mark Conner, Erin Piazza, Brian Filanoski, Rhonda Meredith, Hye Son Yi, Lori Hamanishi, Eduardo Ignacio, Nadine Nelson, Michael Prater, Christine Kang, Lesley Isgur, Margaret Hoang, Gary Geiss, Joseph Beechem

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A136; DOI: 10.1136/jitc-2023-SITC2023.0120
121 Quantifying statistical and systematic uncertainties in predicting clinical outcomes using multiplex immunofluorescence
Jeffrey S Roskes, Margaret Eminizer, Melinda Nagy, Tricia Cottrell, Emily Cohen, Elizabeth Engle, Benjamin Green, Joel Sunshine, Alexander Szalay, Janis Taube

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A137; DOI: 10.1136/jitc-2023-SITC2023.0121
122 Quantification of tumor infiltrating lymphocytes (TILs) from pathology slides reflects molecular immune phenotypes
Ciyue Shen, Shima Nofallah, Jake Conway, Chintan Parmar, Michael G Drage, Fedaa Najdawi, Darpan T Sanghavi, Limin Yu, Raymond Biju, Daniel Borders, Matthew Bronnimann, Laura Chambre, Issac Finberg, Jonathan Glickman, Michael Griffin, Sidharth Gupta, Natalia Harguindeguy, Nhat Le, Stephanie Hennek, Syed Ashar Javed, Christian Kirkup, Miles Markey, Michael Nercessian, Daniel Shenker, Sandhya Srinivasan, Vignesh Valaboju, Samuel AV Mercedes, Bahar Rahsepar, Ryan Leung, Archit Khosla, Benjamin Glass, Amaro Taylor-Weiner, Ylaine Gerardin, John Abel

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A138; DOI: 10.1136/jitc-2023-SITC2023.0122
123 Assessing cytotoxic T cell responses in live tumor fragments (LTF)™ with multiphoton microscopy
Jason Tt. Smith, Jonathan N Ouellette, Anna Kellner, Chao Liu, Ellen Wargowski, Max Shiller, Debra Bloom, Lauren Nettenstrom, Zac Swider, Janey Degnan, Michael Korrer, Matt Conklin, Evan Flietner, Christin Johnson, Lindsay Doebert, Eric Wait, Jonathan Oliner, John Rafter, Christopher D Zahm

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A139; DOI: 10.1136/jitc-2023-SITC2023.0123
124 Location, location, location: spatial analysis of ultrahigh-plex immunofluorescence panel in head and neck cancer
Quyen Vu, Niyati Jhaveri, Aditya Pratapa, Christopher Paustian, Tarsem Moudgil, Venkatesh Rajamanickam, Noah Simons, Oliver Braubach, Rom S Leidner, Bernard A Fox, Shawn M Jensen

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A140; DOI: 10.1136/jitc-2023-SITC2023.0124
125 Single cell spatial analysis and biomarker discovery in hodgkin lymphoma
Alexander Xu, Aixiang Jiang, Tomohiro Aoki, Alicia Gamboa, Lauren Chong, Anthony Colombo, Yifan Yin, Joseph Lownik, Katsuyoshi Takata, Monirath Hav, Christian Steidl, Akil Merchant

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A141; DOI: 10.1136/jitc-2023-SITC2023.0125
126 Mapping neuro-oncological cellular landscape of human and mouse brain tumors using imaging mass cytometry
Nick Zabinyakov, Qanber Raza, Christina Loh

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A142; DOI: 10.1136/jitc-2023-SITC2023.0126
127 A novel multiplex immunohistochemistry (IHC) assay to detect immune checkpoints and biomarkers of T cell exhaustion
Jennifer Ziello, Sasha Tkachev, Lily Vu, Sarah Klein

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A143; DOI: 10.1136/jitc-2023-SITC2023.0127

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