Open access

314 Development of bi-specific chimeric antigen receptor (CAR) T cell therapy for the treatment of AIDS-related B cell malignancies
Ryan Urak, Saghar Pahlavanneshan, Ryotaro Nakamura, John Zaia, John Baird, Mary C Clark, Stephen J Forman, Xiuli Wang

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A357; DOI: 10.1136/jitc-2023-SITC2023.0314
315 iPSC-derived CAR-iNKT cells targeting HER2 show prolonged tumor control and promote durable survival in a tumor xenograft model
Akane Urakami, Koichiro Shioya, Tomokuni Shigeura, Tomio Matsumura, Yuji Mishima, Momoko Okoshi, Haruhiko Koseki, Lilin Zhang

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A358; DOI: 10.1136/jitc-2023-SITC2023.0315
316 STING agonist-induced IL-18 secretion enhances CAR T cell function
Ugur Uslu, Sofia Castelli, Amanda Finck, Charles-Antoine Assenmacher, Lijun Sun, Regina M Young, Zhijian Chen, Carl H June

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A359; DOI: 10.1136/jitc-2023-SITC2023.0316
317 B7-H3-targeted CAR T cell with an inducible caspase 9 suicide gene effectively eradicates uveal melanoma liver metastases
Marco Ventin, Giulia Cattaneo, Jingyu Jia, Shahrzad Arya, Luke Maggs, Yi Sun, Genevieve M Boland, Russell W Jenkins, Bruce R Ksander, Rizwan Haq, Xinhui Wang, Sandra Ryeom, Cristina R Ferrone, Soldano Ferrone

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A360; DOI: 10.1136/jitc-2023-SITC2023.0317
318 Development of CD70 armored Delta-like ligand 3 CAR-T cells for the treatment of small cell lung cancer
Chao Wang, Yu Yang, Ling Chen, Fuwei Jiang, Fanxiang Gao, Cuiqing Yang, Qingyang Wang, Zhuoxiao Cao

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A361; DOI: 10.1136/jitc-2023-SITC2023.0318
319 Transcriptome-guided design of logic-gated CAR T cells for treatment of acute myeloid leukemia
Tess Woodring, Katherine A Freitas, Elena Sotillo, Crystal L Mackall, Rebecca M Richards

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A362-A363; DOI: 10.1136/jitc-2023-SITC2023.0319
320 CAR-T cell manufacturing from fresh whole blood facilitates point-of-care therapeutic cell production
Ying Xiong, Yanping Xie, Yang Liu, Matthew Addington-Hall, Beatrix Ferencz, Tony Luo, Maggie Yates, Oxana Slessareva, Ibeawuchi Oparaocha, Zhongyu Zhu, Boro Dropuli&cacute;, Rimas J Orentas

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A364; DOI: 10.1136/jitc-2023-SITC2023.0320
321 Preclinical potency assessment of SynKIR-110, a mesothelin-specific KIR-CAR T cell therapy for mesothelioma
Jun Xu, Selene Nunez-Cruz, Jacqueline Rivera, Michael Milone, Laura Johnson

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A365; DOI: 10.1136/jitc-2023-SITC2023.0321
322 Preclinical assessment of allogeneic Anti-CD5 γδ CAR-T therapy for T-Cell malignancies
Seung Rok Yu, Hyeong Ji Lee, Jeong Hoon Jeong, Hyeon Jeong Cho, Hyo Bhin Lee, Hyung Cheol Kim, Young Ho Lee

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A366; DOI: 10.1136/jitc-2023-SITC2023.0322
323 Preclinical development of AB-1015, an integrated circuit T cell therapy containing an ALPG/MSLN logic gate and FAS/PTPN2 shRNA-miR, for the treatment of ovarian cancer
Hongruo Yun, Jasper Williams, Dina Polyak, James Zhang, Michelle Nguyen, Irene Scarfo, Jessica Fuhriman, Aaron Cooper, Jennifer McDevitt, Stephen Santoro, Jun Feng

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A367; DOI: 10.1136/jitc-2023-SITC2023.0323

Main menu

Open access

Pages

Log in using your username and password

Main menu

Log in using your username and password

You are here

Open access

Pages