- T1-Weighted, Dynamic Contrast-Enhanced MR Perfusion Imaging Can Differentiate between Treatment Success and Failure in Spine Metastases Undergoing Radiation Therapy
Routine MRI techniques are rather limited in assessing treatment response versus disease progression following radiation therapy as lesion size often fluctuates after both successful and unsuccessful treatment. In this study, dynamic contrast-enhanced MRI perfusion parameters were used to predict treatment success or failure regarding spinal osseous metastases and to show the concordance with lesion-size measurements in the determination of treatment success or failure. The authors found there were significant differences in the change in plasma volume following radiation treatment between their clinical response and persistent disease groups. Additionally, they demonstrated that plasma volume had a higher specificity than size measurements.
- Prevalence and Characteristics of Intracranial Aneurysms in Hereditary Hemorrhagic Telangiectasia
In this retrospective study, the authors evaluated the prevalence and characteristics of intracranial aneurysms in patients with hereditary hemorrhagic telangiectasia with brain vascular malformations. In their study cohort of 180 patients with HHT and brain vascular malformations, the authors demonstrated that the prevalence of intracranial aneurysm in hereditary hemorrhagic telangiectasia is comparable with that in the general population without clear association with shunting brain vascular malformations.
- Prevalence of Cochlear-Facial and Other Non-Superior Semicircular Canal Third Window Dehiscence on High-Resolution Temporal Bone CT
This study of 500 patients found the prevalence of non-SSCD on high-resolution CT in asymptomatic individuals to be 1.6% for CFD and 8.0% for JVD as compared with the rate in patients with audiologic or vestibular symptoms (2.9% for CFD and 7.8% for JVD). There was no statistically significant difference in the rates of radiologic findings between patients with reported symptoms suggestive of a possible third window syndrome and those without auditory or vestibular symptoms.
- DWI-Detected Ischemic Lesions after Endovascular Treatment for Cerebral Aneurysms: An Updated Systematic Review and Meta-analysis
This systematic review and meta-analysis found the incidence of new postprocedural DWI-detected ischemic lesions after endovascular treatment for intracranial aneurysms to be 47.0% (95% CI, 39.6%–55.8%), regardless of the endovascular procedure used. Studies have shown that almost half of these lesions are asymptomatic, and if small (<5 mm), these lesions have been shown to regress without negative effect on clinical outcome.
- Factors Predictive of Treatment Success in CT-Guided Fibrin Occlusion of CSF-Venous Fistulas: A Multicenter Retrospective Cross-Sectional Study
Multi-institutional retrospective evaluation of patients with CSF-to-venous fistulas treated with CT-guided fibrin glue treatment showed that treatment success may be in part driven by whether the spread of fibrin injectate matches the target drainage pathway of the CVF.