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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleAdult Brain
Open Access

Peak Width of Skeletonized Mean Diffusivity as Neuroimaging Biomarker in Cerebral Amyloid Angiopathy

N. Raposo, M.C. Zanon Zotin, D. Schoemaker, L. Xiong, P. Fotiadis, A. Charidimou, M. Pasi, G. Boulouis, K. Schwab, M.D. Schirmer, M.R. Etherton, M.E. Gurol, S.M. Greenberg, M. Duering and A. Viswanathan
American Journal of Neuroradiology March 2021, DOI: https://doi.org/10.3174/ajnr.A7042
N. Raposo
aFrom the Stroke Research Center (N.R., M.C.Z.Z., D.S., L.X., P.F., A.C., K.S., M.D.S., M.R.E., M.E.G., S.M.G., A.V.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
bDepartment of Neurology (N.R.), Centre Hospitalier Universitaire de Toulouse, Toulouse, France
cToulouse NeuroImaging Center (N.R.), Université de Toulouse, Institut National de la Santé et de la Recherche Médicale, Toulouse, Université Paul Sabatier, France
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M.C. Zanon Zotin
aFrom the Stroke Research Center (N.R., M.C.Z.Z., D.S., L.X., P.F., A.C., K.S., M.D.S., M.R.E., M.E.G., S.M.G., A.V.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
dCenter for Imaging Sciences and Medical Physics (M.C.Z.Z.). Department of Medical Imaging, Hematology and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
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D. Schoemaker
aFrom the Stroke Research Center (N.R., M.C.Z.Z., D.S., L.X., P.F., A.C., K.S., M.D.S., M.R.E., M.E.G., S.M.G., A.V.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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L. Xiong
aFrom the Stroke Research Center (N.R., M.C.Z.Z., D.S., L.X., P.F., A.C., K.S., M.D.S., M.R.E., M.E.G., S.M.G., A.V.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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P. Fotiadis
aFrom the Stroke Research Center (N.R., M.C.Z.Z., D.S., L.X., P.F., A.C., K.S., M.D.S., M.R.E., M.E.G., S.M.G., A.V.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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A. Charidimou
aFrom the Stroke Research Center (N.R., M.C.Z.Z., D.S., L.X., P.F., A.C., K.S., M.D.S., M.R.E., M.E.G., S.M.G., A.V.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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M. Pasi
eDepartment of Neurology (M.P.), Centre Hospitalier Universitaire de Lille, Lille, France
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G. Boulouis
fDepartment of Neuroradiology (G.B.), Centre Hospitalier Sainte-Anne, Université Paris-Descartes, Paris, France
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K. Schwab
aFrom the Stroke Research Center (N.R., M.C.Z.Z., D.S., L.X., P.F., A.C., K.S., M.D.S., M.R.E., M.E.G., S.M.G., A.V.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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M.D. Schirmer
aFrom the Stroke Research Center (N.R., M.C.Z.Z., D.S., L.X., P.F., A.C., K.S., M.D.S., M.R.E., M.E.G., S.M.G., A.V.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
gComputer Science and Artificial Intelligence Lab (M.D.S.), Massachusetts Institute of Technology, Boston, Massachusetts
hDepartment of Population Health Sciences (M.D.S.), German Center for Neurodegenerative Diseases, Bonn, Germany
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M.R. Etherton
aFrom the Stroke Research Center (N.R., M.C.Z.Z., D.S., L.X., P.F., A.C., K.S., M.D.S., M.R.E., M.E.G., S.M.G., A.V.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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M.E. Gurol
aFrom the Stroke Research Center (N.R., M.C.Z.Z., D.S., L.X., P.F., A.C., K.S., M.D.S., M.R.E., M.E.G., S.M.G., A.V.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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S.M. Greenberg
aFrom the Stroke Research Center (N.R., M.C.Z.Z., D.S., L.X., P.F., A.C., K.S., M.D.S., M.R.E., M.E.G., S.M.G., A.V.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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M. Duering
iMedical Image Analysis Center (MIAC) and Quantitative Biomedical Imaging Group (M.D.), Department of Biomedical Engineering, University of Basel, Basel, Switzerland
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A. Viswanathan
aFrom the Stroke Research Center (N.R., M.C.Z.Z., D.S., L.X., P.F., A.C., K.S., M.D.S., M.R.E., M.E.G., S.M.G., A.V.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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Article Information

DOI 
https://doi.org/10.3174/ajnr.A7042
PubMed 
33664113

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received July 17, 2020
  • Accepted after revision November 20, 2020
  • Published online March 4, 2021.

Article Versions

  • You are currently viewing a Latest version of this article (March 4, 2021 - 09:02).
  • View the most recent version of this article
Copyright & Usage 
© 2021 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org

Author Information

  1. N. Raposoa,b,c,
  2. M.C. Zanon Zotina,d,
  3. D. Schoemakera,
  4. L. Xionga,
  5. P. Fotiadisa,
  6. A. Charidimoua,
  7. M. Pasie,
  8. G. Boulouisf,
  9. K. Schwaba,
  10. M.D. Schirmera,g,h,
  11. M.R. Ethertona,
  12. M.E. Gurola,
  13. S.M. Greenberga,
  14. M. Dueringi and
  15. A. Viswanathana
  1. aFrom the Stroke Research Center (N.R., M.C.Z.Z., D.S., L.X., P.F., A.C., K.S., M.D.S., M.R.E., M.E.G., S.M.G., A.V.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
  2. bDepartment of Neurology (N.R.), Centre Hospitalier Universitaire de Toulouse, Toulouse, France
  3. cToulouse NeuroImaging Center (N.R.), Université de Toulouse, Institut National de la Santé et de la Recherche Médicale, Toulouse, Université Paul Sabatier, France
  4. dCenter for Imaging Sciences and Medical Physics (M.C.Z.Z.). Department of Medical Imaging, Hematology and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
  5. eDepartment of Neurology (M.P.), Centre Hospitalier Universitaire de Lille, Lille, France
  6. fDepartment of Neuroradiology (G.B.), Centre Hospitalier Sainte-Anne, Université Paris-Descartes, Paris, France
  7. gComputer Science and Artificial Intelligence Lab (M.D.S.), Massachusetts Institute of Technology, Boston, Massachusetts
  8. hDepartment of Population Health Sciences (M.D.S.), German Center for Neurodegenerative Diseases, Bonn, Germany
  9. iMedical Image Analysis Center (MIAC) and Quantitative Biomedical Imaging Group (M.D.), Department of Biomedical Engineering, University of Basel, Basel, Switzerland
  1. Please address correspondence to Nicolas Raposo, MD, PhD, Service de Neurologie, Hôpital Pierre-Paul Riquet, Centre Hospitalier Universitaire de Toulouse, Place Baylac, 31059 Toulouse Cedex 9, France; e-mail: raposo.n{at}chu-toulouse.fr
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Funding

  • Harvard University Committee on General Scholarship

    Arthur Sachs Scholarship
  • European Union’s Horizon 2020 research and innovation program

    Marie Sklodowska-Curie grant agreement No 753896
  • National Institutes of Health

    K23AG02872605; P50AG005134; R01AG026484; R01AG047975
  • Fulbright Scholarship

  • Philippe Foundation

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N. Raposo, M.C. Zanon Zotin, D. Schoemaker, L. Xiong, P. Fotiadis, A. Charidimou, M. Pasi, G. Boulouis, K. Schwab, M.D. Schirmer, M.R. Etherton, M.E. Gurol, S.M. Greenberg, M. Duering, A. Viswanathan
Peak Width of Skeletonized Mean Diffusivity as Neuroimaging Biomarker in Cerebral Amyloid Angiopathy
American Journal of Neuroradiology Mar 2021, DOI: 10.3174/ajnr.A7042

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Peak Width of Skeletonized Mean Diffusivity as Neuroimaging Biomarker in Cerebral Amyloid Angiopathy
N. Raposo, M.C. Zanon Zotin, D. Schoemaker, L. Xiong, P. Fotiadis, A. Charidimou, M. Pasi, G. Boulouis, K. Schwab, M.D. Schirmer, M.R. Etherton, M.E. Gurol, S.M. Greenberg, M. Duering, A. Viswanathan
American Journal of Neuroradiology Mar 2021, DOI: 10.3174/ajnr.A7042
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