Article Figures & Data
Figures
- Fig 1.
Flowchart depicting patient selection according to predefined inclusion and exclusion criteria. IVT indicates intravenous thrombolysis.
- Fig 2.
Distribution of mRS scores at 90 days.
Tables
Control Group (n = 780) WUS (n = 128) DUS (n = 165) P Valuea P Valueb mRS 0–2 at 3 mo (No.) (%) 299 (38.3) 46 (35.9) 45 (27.3) .025 (A) .625 (B) .007 (C) .127 In-hospital mortality (No.) (%) 145 (18.9) 16 (12.6) 38 (23.3) .067 NA All-cause mortality at 3 mo (No.) (%) 207 (26.5) 29 (22.7) 52 (31.5) .224 NA sICH (No.) (%) 42 (5.5) 3 (2.4) 10 (6.3) .292 NA Control Group (n = 780) WUS[advanced] (n = 68) DUS[advanced] (n = 63) P Valuea P Valueb A) CTP or MRI [advanced] mRS 0–2 (3 mo) (No.) (%) 299 (38.3) 32 (47.1) 23 (36.5) .344 NA In-hospital mortality (No.) (%) 145 (18.9) 5 (7.5) 8 (12.7) .031 (A) 0.019 (B) .309 (C) .388 All-cause mortality (3 mo) (No.) (%) 207 (26.5) 11 (16.2) 13 (20.6) .120 NA sICH (No.) (%) 42 (5.5) 1 (1.5) 2 (3.3) .380 NA Control Group (n = 780) WUS[mri] (n = 47) DUS[mri] (n = 52) B) MRI [mri] mRS 0–2 (3 mo) (No.) (%) 299 (38.3) 24 (51.1) 20 (38.5) .216 NA In-hospital mortality (No.) (%) 145 (18.9) 2 (4.3) 8 (15.4) .024 (A) .009 (B) .713 (C) .204 All-cause mortality (3 mo) (No.) (%) 207 (26.5) 6 (12.8) 12 (23.1) .093 NA sICH (No.) (%) 42 (5.5) 1 (2.2) 2 (4.0) .808 NA Control [mri] (n = 170) WUS[mri] (n = 47) DUS[mri] (n = 52) C) MRI compared with selected controls [mri] mRS 0–2 (3 mo) (No.) (%) 83 (48.8) 24 (51.1) 20 (38.5) .357 NA In-hospital mortality (No.) (%) 19 (11.5) 2 (4.3) 8 (15.4) .211 NA All-cause mortality (3 mo) (No.) (%) 34 (20.0) 6 (12.8) 12 (23.1) .385 NA sICH (No.) (%) 5 (3.0) 1 (2.2) 2 (4.0) .875 NA WUS[advanced] (n = 68) Non-WUS[advanced] (n = 60) OR (95% CI), P Value A) WUS treated after CTP or MRI [advanced] compared with the remaining WUS [non-advanced] mRS 0–2 (3 mo) (No.) (%) 32 (47.1) 14 (23.3) 2.92 (1.32–6.45), .006 In-hospital mortality (No.) (%) 5 (7.5) 11 (18.3) 0.36 (0.11–1.12), .106 All-cause mortality (3 mo) (No.) (%) 11 (16.2) 18 (30.0) 0.45 (0.19–1.07), .090 sICH (No.) (%) 1 (1.5) 2 (3.4) 0.43 (0.04–4.95), .599 DUS[advanced] (n = 63) Non-DUS[advanced] (n = 102) B) DUS treated after CTP and MRI [advanced] compared with the remaining WUS [non-advanced] mRS 0–2 (3 mo) (No.) (%) 23 (36.1) 22 (21.6) 2.09 (1.03–4.25), .048 In-hospital mortality (No.) (%) 8 (12.7) 30 (30.0) 0.34 (0.14–0.82), .013 All-cause mortality (3 mo) (No.) (%) 13 (20.6) 39 (38.2) 0.42 (0.20–0.88), .025 sICH (No.) (%) 2 (3.3) 8 (8.1) 0.39 (0.08–1.90), .320 WUS[mri] (n = 47) Non-WUS[mri] (n = 81) C) WUS treated after MRI [mri] compared with the remaining WUS [non-mri] mRS 0–2 (3 mo) (No.) (%) 24 (51.1) 22 (27.2) 2.80 (1.28–6.10), .008 In-hospital mortality (No.) (%) 2 (4.3) 14 (17.3) 0.22 (0.05–1.04), .049 All-cause mortality (3 mo) (No.) (%) 6 (12.8) 23 (28.4) 0.37 (0.14–1.01), .050 sICH (No.) (%) 1 (2.2) 2 (2.6) 0.84 (0.07–9.68), 1.000 DUS[mri] (n = 52) Non-DUS[mri] (n = 113) D) DUS treated after MRI [mri] compared with the remaining DUS [non-mri] mRS 0–2 (3 mo) (No.) (%) 20 (38.5) 25 (22.1) 2.20 (1.06–4.55), .038 In-hospital mortality (No.) (%) 8 (15.4) 30 (27.0) 0.49 (0.21–1.17), .115 All-cause mortality (3 mo) (No.) (%) 12 (23.1) 40 (35.4) 0.55 (0.27–1.17), .149 sICH (No.) (%) 2 (4.0) 8 (7.3) 0.53 (0.11–2.62), .726 Note:—sICH indicates symptomatic intracranial hemorrhage.
