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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleArtificial Intelligence
Open Access

Automated Segmentation of MRI White Matter Hyperintensities in 8421 Patients with Acute Ischemic Stroke

Hosung Kim, Wi-Sun Ryu, Dawid Schellingerhout, Jonghyeok Park, Jinyong Chung, Sang-Wuk Jeong, Dong-Seok Gwak, Beom Joon Kim, Joon-Tae Kim, Keun-Sik Hong, Kyung Bok Lee, Tai Hwan Park, Jong-Moo Park, Kyusik Kang, Yong-Jin Cho, Byung-Chul Lee, Kyung-Ho Yu, Mi Sun Oh, Soo Joo Lee, Jae-Kwan Cha, Dae-Hyun Kim, Jun Lee, Man Seok Park, Hee-Joon Bae and Dong-Eog Kim
American Journal of Neuroradiology December 2024, 45 (12) 1885-1894; DOI: https://doi.org/10.3174/ajnr.A8418
Hosung Kim
aFrom the USC Stevens Neuroimaging and Informatics Institute (H.K.), Keck School of Medicine of USC, University of Southern California, Los Angeles, California
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Wi-Sun Ryu
bArtificial Intelligence Research Center (W.-S.R, J.P.), JLK Inc, Seoul, Republic of Korea
cNational Priority Research Center for Stroke and Department of Neurology (W.-S.R, J.C., S.-W.J., D.-S.G., D.-E.K.), Dongguk University Ilsan Hospital, Goyang, Republic of Korea
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Dawid Schellingerhout
dDepartment of Neuroradiology and Imaging Physics (D.S.), The University of Texas M.D. Anderson Cancer Center, Houston, Texas
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Jonghyeok Park
bArtificial Intelligence Research Center (W.-S.R, J.P.), JLK Inc, Seoul, Republic of Korea
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Jinyong Chung
cNational Priority Research Center for Stroke and Department of Neurology (W.-S.R, J.C., S.-W.J., D.-S.G., D.-E.K.), Dongguk University Ilsan Hospital, Goyang, Republic of Korea
eBioimaging Data Curation Center (J.C., D.-S.G., D.-E.K.), KOREA-BioData Station, Daejeon, Republic of Korea
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Sang-Wuk Jeong
cNational Priority Research Center for Stroke and Department of Neurology (W.-S.R, J.C., S.-W.J., D.-S.G., D.-E.K.), Dongguk University Ilsan Hospital, Goyang, Republic of Korea
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Dong-Seok Gwak
cNational Priority Research Center for Stroke and Department of Neurology (W.-S.R, J.C., S.-W.J., D.-S.G., D.-E.K.), Dongguk University Ilsan Hospital, Goyang, Republic of Korea
eBioimaging Data Curation Center (J.C., D.-S.G., D.-E.K.), KOREA-BioData Station, Daejeon, Republic of Korea
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Beom Joon Kim
fDepartment of Neurology (B.J.K., H.-J.B.), Seoul National University Bundang Hospital, Seongnam, Republic of Korea
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Joon-Tae Kim
gDepartment of Neurology (J.-T.K., M.S.P.,), Chonnam National University Hospital, Gwangju, Republic of Korea
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Keun-Sik Hong
hDepartment of Neurology (K.-S.H., Y,-J.C.), Inje University Ilsan Paik Hospital, Goyang, Republic of Korea
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Kyung Bok Lee
iDepartment of Neurology (K.B.L.), Soonchunhyang University Hospital, Seoul, Republic of Korea
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Tai Hwan Park
jDepartment of Neurology (T.H.P.), Seoul Medical Center, Seoul, Republic of Korea
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Jong-Moo Park
kDepartment of Neurology (J.-M.P.), Uijeongbu Eulji Medical Center, Uijeongbu, Republic of Korea
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Kyusik Kang
lDepartment of Neurology (K.K.), Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Republic of Korea
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Yong-Jin Cho
hDepartment of Neurology (K.-S.H., Y,-J.C.), Inje University Ilsan Paik Hospital, Goyang, Republic of Korea
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Byung-Chul Lee
mDepartment of Neurology (B.-C.L., K.-H.Y., M.S.O.), Hallym University Sacred Heart Hospital, Anyang, Republic of Korea
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Kyung-Ho Yu
mDepartment of Neurology (B.-C.L., K.-H.Y., M.S.O.), Hallym University Sacred Heart Hospital, Anyang, Republic of Korea
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Mi Sun Oh
mDepartment of Neurology (B.-C.L., K.-H.Y., M.S.O.), Hallym University Sacred Heart Hospital, Anyang, Republic of Korea
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Soo Joo Lee
nDepartment of Neurology (S.J.L.), Eulji University Hospital, Daejeon, Republic of Korea
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Jae-Kwan Cha
oDepartment of Neurology (J.-K.C., D.-H.K.), Dong-A University Hospital, Busan, Republic of Korea
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Dae-Hyun Kim
oDepartment of Neurology (J.-K.C., D.-H.K.), Dong-A University Hospital, Busan, Republic of Korea
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Jun Lee
pDepartment of Neurology (J.L.), Yeungnam University Hospital, Daegu, Republic of Korea.
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Man Seok Park
gDepartment of Neurology (J.-T.K., M.S.P.,), Chonnam National University Hospital, Gwangju, Republic of Korea
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Hee-Joon Bae
fDepartment of Neurology (B.J.K., H.-J.B.), Seoul National University Bundang Hospital, Seongnam, Republic of Korea
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Dong-Eog Kim
cNational Priority Research Center for Stroke and Department of Neurology (W.-S.R, J.C., S.-W.J., D.-S.G., D.-E.K.), Dongguk University Ilsan Hospital, Goyang, Republic of Korea
eBioimaging Data Curation Center (J.C., D.-S.G., D.-E.K.), KOREA-BioData Station, Daejeon, Republic of Korea
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Article Information

vol. 45 no. 12 1885-1894
DOI 
https://doi.org/10.3174/ajnr.A8418
PubMed 
39013565

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received February 28, 2024
  • Accepted after revision July 9, 2024
  • Published online December 9, 2024.

Article Versions

  • Latest version (July 16, 2024 - 05:52).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2024 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org

Author Information

  1. Hosung Kima,
  2. Wi-Sun Ryub,c,
  3. Dawid Schellingerhoutd,
  4. Jonghyeok Parkb,
  5. Jinyong Chungc,e,
  6. Sang-Wuk Jeongc,
  7. Dong-Seok Gwakc,e,
  8. Beom Joon Kimf,
  9. Joon-Tae Kimg,
  10. Keun-Sik Hongh,
  11. Kyung Bok Leei,
  12. Tai Hwan Parkj,
  13. Jong-Moo Parkk,
  14. Kyusik Kangl,
  15. Yong-Jin Choh,
  16. Byung-Chul Leem,
  17. Kyung-Ho Yum,
  18. Mi Sun Ohm,
  19. Soo Joo Leen,
  20. Jae-Kwan Chao,
  21. Dae-Hyun Kimo,
  22. Jun Leep,
  23. Man Seok Parkg,
  24. Hee-Joon Baef and
  25. Dong-Eog Kimc,e
  1. aFrom the USC Stevens Neuroimaging and Informatics Institute (H.K.), Keck School of Medicine of USC, University of Southern California, Los Angeles, California
  2. bArtificial Intelligence Research Center (W.-S.R, J.P.), JLK Inc, Seoul, Republic of Korea
  3. cNational Priority Research Center for Stroke and Department of Neurology (W.-S.R, J.C., S.-W.J., D.-S.G., D.-E.K.), Dongguk University Ilsan Hospital, Goyang, Republic of Korea
  4. dDepartment of Neuroradiology and Imaging Physics (D.S.), The University of Texas M.D. Anderson Cancer Center, Houston, Texas
  5. eBioimaging Data Curation Center (J.C., D.-S.G., D.-E.K.), KOREA-BioData Station, Daejeon, Republic of Korea
  6. fDepartment of Neurology (B.J.K., H.-J.B.), Seoul National University Bundang Hospital, Seongnam, Republic of Korea
  7. gDepartment of Neurology (J.-T.K., M.S.P.,), Chonnam National University Hospital, Gwangju, Republic of Korea
  8. hDepartment of Neurology (K.-S.H., Y,-J.C.), Inje University Ilsan Paik Hospital, Goyang, Republic of Korea
  9. iDepartment of Neurology (K.B.L.), Soonchunhyang University Hospital, Seoul, Republic of Korea
  10. jDepartment of Neurology (T.H.P.), Seoul Medical Center, Seoul, Republic of Korea
  11. kDepartment of Neurology (J.-M.P.), Uijeongbu Eulji Medical Center, Uijeongbu, Republic of Korea
  12. lDepartment of Neurology (K.K.), Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Republic of Korea
  13. mDepartment of Neurology (B.-C.L., K.-H.Y., M.S.O.), Hallym University Sacred Heart Hospital, Anyang, Republic of Korea
  14. nDepartment of Neurology (S.J.L.), Eulji University Hospital, Daejeon, Republic of Korea
  15. oDepartment of Neurology (J.-K.C., D.-H.K.), Dong-A University Hospital, Busan, Republic of Korea
  16. pDepartment of Neurology (J.L.), Yeungnam University Hospital, Daegu, Republic of Korea.
  1. Please address correspondence to Dong-Eog Kim, MD, PhD, Department of Neurology, Dongguk University Ilsan Hospital, 27, Dongguk-ro, Ilsandong-gu, Goyang, South Korea; e-mail: kdongeog{at}duih.org
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Funding

  • National Research Foundation of Korea

    KMDF_PR_20200901_0098; NRF-2020R1A2C3008295; NRF-2021R1A6A1A03038865

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Hosung Kim, Wi-Sun Ryu, Dawid Schellingerhout, Jonghyeok Park, Jinyong Chung, Sang-Wuk Jeong, Dong-Seok Gwak, Beom Joon Kim, Joon-Tae Kim, Keun-Sik Hong, Kyung Bok Lee, Tai Hwan Park, Jong-Moo Park, Kyusik Kang, Yong-Jin Cho, Byung-Chul Lee, Kyung-Ho Yu, Mi Sun Oh, Soo Joo Lee, Jae-Kwan Cha, Dae-Hyun Kim, Jun Lee, Man Seok Park, Hee-Joon Bae, Dong-Eog Kim
Automated Segmentation of MRI White Matter Hyperintensities in 8421 Patients with Acute Ischemic Stroke
American Journal of Neuroradiology Dec 2024, 45 (12) 1885-1894; DOI: 10.3174/ajnr.A8418

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AutoSegmentation of Stroke MRI Hyperintensities
Hosung Kim, Wi-Sun Ryu, Dawid Schellingerhout, Jonghyeok Park, Jinyong Chung, Sang-Wuk Jeong, Dong-Seok Gwak, Beom Joon Kim, Joon-Tae Kim, Keun-Sik Hong, Kyung Bok Lee, Tai Hwan Park, Jong-Moo Park, Kyusik Kang, Yong-Jin Cho, Byung-Chul Lee, Kyung-Ho Yu, Mi Sun Oh, Soo Joo Lee, Jae-Kwan Cha, Dae-Hyun Kim, Jun Lee, Man Seok Park, Hee-Joon Bae, Dong-Eog Kim
American Journal of Neuroradiology Dec 2024, 45 (12) 1885-1894; DOI: 10.3174/ajnr.A8418
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This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Artificial intelligence in neuroimaging with a focus on acute and degenerative neurologic disorders: a narrative review
    Leonard Sunwoo, Byung Se Choi
    Journal of the Korean Medical Association 2025 68 5
  • Segmentation of Leukoaraiosis on Noncontrast Head CT Using CT‐MRI Paired Data Without Human Annotation
    Wi‐Sun Ryu, Jae W. Song, Jae‐Sung Lim, Ju Hyung Lee, Leonard Sunwoo, Dongmin Kim, Dong‐Eog Kim, Hee‐Joon Bae, Myungjae Lee, Beom Joon Kim
    Brain and Behavior 2025 15 6

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