Article Figures & Data
Figures
- FIG 1.
The 2 BOLD signal (a.u.) waveforms in a voxel over the MCA versus time in a representative participant for Thx-dOHb (A) and GBCA (B). A.u. indicates arbitrary units.
- FIG 2.
Bland-Altman plots comparing GBCA and THx-dOHb differences for perfusion metrics MTT, rCBF, and rCBV in GM and WM. The solid blue line depicts the mean, the dotted blue lines represent the 95% limits of agreement, and the red line represents the regression line.
- FIG 3.
The affected-versus-nonaffected hemispheric perfusion metrics for GBCA and THx-dOHb for 8 participants who have unilateral steno-occlusive disease (patients 6 and 7 have bilateral disease and were excluded) in the MCA in the GM (on the right) and WM (on the left). The trends of affected-versus-unaffected hemispheres across both techniques are comparable. a.u. indicates arbitrary units.
- FIG 4.
Perfusion maps of MTT, rCBF, and rCBV of a 71-year-old male participant (ID 1) with a right ICA occlusion comparing GBCA (A) and THx-dOHb (B). a.u. indicates arbitrary units.
Tables
Average measures of ΔS in percentages and the CNR calculated for GBCA and THx-dOHb for the 10 participants
ΔS (%) CNR GM WM GM WM GBCA 25.20 (SD, 8.08) 14.78 (SD, 4.36) 11.21 (SD, 3.76) 8.17 (SD, 2.64) THx-dOHb 5.71 (SD, 1.60) 2.87 (SD, 0.92) 6.33 (SD, 1.22) 6.41 (SD, 1.64) P value .002 .002 .004 .002
