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Research ArticleNeurovascular/Stroke Imaging
Open Access

Assessing Perfusion in Steno-Occlusive Cerebrovascular Disease Using Transient Hypoxia-Induced Deoxyhemoglobin as a Dynamic Susceptibility Contrast Agent

Ece Su Sayin, James Duffin, Vittorio Stumpo, Jacopo Bellomo, Marco Piccirelli, Julien Poublanc, Vepeson Wijeya, Andrea Para, Athina Pangalu, Andrea Bink, Bence Nemeth, Zsolt Kulcsar, David J. Mikulis, Joseph A. Fisher, Olivia Sobczyk and Jorn Fierstra
American Journal of Neuroradiology January 2024, 45 (1) 37-43; DOI: https://doi.org/10.3174/ajnr.A8068
Ece Su Sayin
aFrom the Department of Physiology (E.S.S., J.D., J.A.F.), University of Toronto, Toronto, Ontario, Canada
cJoint Department of Medical Imaging and the Functional Neuroimaging Lab (E.S.S., J.P., V.W., A. Para, D.J.M., O.S.), University Health Network, Toronto, Ontario, Canada
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  • ORCID record for Ece Su Sayin
James Duffin
aFrom the Department of Physiology (E.S.S., J.D., J.A.F.), University of Toronto, Toronto, Ontario, Canada
dDepartment of Anesthesia and Pain Management (J.D., J.A.F.), University Health Network, University of Toronto, Toronto, Ontario, Canada
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Vittorio Stumpo
eDepartment of Neurosurgery (V.S., J.B. J.F.), University Hospital Zurich, University of Zurich, Zurich, Switzerland
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Jacopo Bellomo
eDepartment of Neurosurgery (V.S., J.B. J.F.), University Hospital Zurich, University of Zurich, Zurich, Switzerland
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Marco Piccirelli
fDepartment of Neuroradiology and Clinical Neuroscience Center (M.P., A. Pangalu, A.B., B.N., Z.K.), University Hospital Zurich, University of Zurich, Zurich, Switzerland
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Julien Poublanc
cJoint Department of Medical Imaging and the Functional Neuroimaging Lab (E.S.S., J.P., V.W., A. Para, D.J.M., O.S.), University Health Network, Toronto, Ontario, Canada
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Vepeson Wijeya
cJoint Department of Medical Imaging and the Functional Neuroimaging Lab (E.S.S., J.P., V.W., A. Para, D.J.M., O.S.), University Health Network, Toronto, Ontario, Canada
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Andrea Para
cJoint Department of Medical Imaging and the Functional Neuroimaging Lab (E.S.S., J.P., V.W., A. Para, D.J.M., O.S.), University Health Network, Toronto, Ontario, Canada
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Athina Pangalu
fDepartment of Neuroradiology and Clinical Neuroscience Center (M.P., A. Pangalu, A.B., B.N., Z.K.), University Hospital Zurich, University of Zurich, Zurich, Switzerland
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Andrea Bink
fDepartment of Neuroradiology and Clinical Neuroscience Center (M.P., A. Pangalu, A.B., B.N., Z.K.), University Hospital Zurich, University of Zurich, Zurich, Switzerland
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Bence Nemeth
fDepartment of Neuroradiology and Clinical Neuroscience Center (M.P., A. Pangalu, A.B., B.N., Z.K.), University Hospital Zurich, University of Zurich, Zurich, Switzerland
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Zsolt Kulcsar
fDepartment of Neuroradiology and Clinical Neuroscience Center (M.P., A. Pangalu, A.B., B.N., Z.K.), University Hospital Zurich, University of Zurich, Zurich, Switzerland
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David J. Mikulis
bDepartment of Medical Biophysics (D.J.M.), University of Toronto, Toronto, Ontario, Canada.
cJoint Department of Medical Imaging and the Functional Neuroimaging Lab (E.S.S., J.P., V.W., A. Para, D.J.M., O.S.), University Health Network, Toronto, Ontario, Canada
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Joseph A. Fisher
aFrom the Department of Physiology (E.S.S., J.D., J.A.F.), University of Toronto, Toronto, Ontario, Canada
dDepartment of Anesthesia and Pain Management (J.D., J.A.F.), University Health Network, University of Toronto, Toronto, Ontario, Canada
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Olivia Sobczyk
cJoint Department of Medical Imaging and the Functional Neuroimaging Lab (E.S.S., J.P., V.W., A. Para, D.J.M., O.S.), University Health Network, Toronto, Ontario, Canada
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Jorn Fierstra
eDepartment of Neurosurgery (V.S., J.B. J.F.), University Hospital Zurich, University of Zurich, Zurich, Switzerland
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Article Information

vol. 45 no. 1 37-43
DOI 
https://doi.org/10.3174/ajnr.A8068
PubMed 
38164571

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received July 21, 2023
  • Accepted after revision November 1, 2023
  • Published online December 29, 2023.

Article Versions

  • Latest version (December 21, 2023 - 09:38).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2024 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org

Author Information

  1. Ece Su Sayina,c,
  2. James Duffina,d,
  3. Vittorio Stumpoe,
  4. Jacopo Bellomoe,
  5. Marco Piccirellif,
  6. Julien Poublancc,
  7. Vepeson Wijeyac,
  8. Andrea Parac,
  9. Athina Pangaluf,
  10. Andrea Binkf,
  11. Bence Nemethf,
  12. Zsolt Kulcsarf,
  13. David J. Mikulisb,c,
  14. Joseph A. Fishera,d,
  15. Olivia Sobczykc and
  16. Jorn Fierstrae
  1. aFrom the Department of Physiology (E.S.S., J.D., J.A.F.), University of Toronto, Toronto, Ontario, Canada
  2. bDepartment of Medical Biophysics (D.J.M.), University of Toronto, Toronto, Ontario, Canada.
  3. cJoint Department of Medical Imaging and the Functional Neuroimaging Lab (E.S.S., J.P., V.W., A. Para, D.J.M., O.S.), University Health Network, Toronto, Ontario, Canada
  4. dDepartment of Anesthesia and Pain Management (J.D., J.A.F.), University Health Network, University of Toronto, Toronto, Ontario, Canada
  5. eDepartment of Neurosurgery (V.S., J.B. J.F.), University Hospital Zurich, University of Zurich, Zurich, Switzerland
  6. fDepartment of Neuroradiology and Clinical Neuroscience Center (M.P., A. Pangalu, A.B., B.N., Z.K.), University Hospital Zurich, University of Zurich, Zurich, Switzerland
  1. Please address correspondence to Olivia Sobczyk, PhD, University Health Network, Toronto General Hospital, Toronto, Ontario, Canada, 200 Elizabeth St, Toronto, ON, Canada M5G 2C4, P: 647-255-1410; e-mail: olivia.sobczyk{at}uhn.ca
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Ece Su Sayin, James Duffin, Vittorio Stumpo, Jacopo Bellomo, Marco Piccirelli, Julien Poublanc, Vepeson Wijeya, Andrea Para, Athina Pangalu, Andrea Bink, Bence Nemeth, Zsolt Kulcsar, David J. Mikulis, Joseph A. Fisher, Olivia Sobczyk, Jorn Fierstra
Assessing Perfusion in Steno-Occlusive Cerebrovascular Disease Using Transient Hypoxia-Induced Deoxyhemoglobin as a Dynamic Susceptibility Contrast Agent
American Journal of Neuroradiology Jan 2024, 45 (1) 37-43; DOI: 10.3174/ajnr.A8068

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Assessing Perfusion in Cerebrovascular Disease
Ece Su Sayin, James Duffin, Vittorio Stumpo, Jacopo Bellomo, Marco Piccirelli, Julien Poublanc, Vepeson Wijeya, Andrea Para, Athina Pangalu, Andrea Bink, Bence Nemeth, Zsolt Kulcsar, David J. Mikulis, Joseph A. Fisher, Olivia Sobczyk, Jorn Fierstra
American Journal of Neuroradiology Jan 2024, 45 (1) 37-43; DOI: 10.3174/ajnr.A8068
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