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Research ArticleBrain Tumor Imaging

Mesoscopic Assessment of Microstructure in Glioblastomas and Metastases by Merging Advanced Diffusion Imaging with Immunohistopathology

Urs Würtemberger, Daniel Erny, Alexander Rau, Jonas A. Hosp, Veysel Akgün, Marco Reisert, Valerij G. Kiselev, Jürgen Beck, Sonja Jankovic, Peter C. Reinacher, Marc Hohenhaus, Horst Urbach, Martin Diebold and Theo Demerath
American Journal of Neuroradiology November 2023, 44 (11) 1262-1269; DOI: https://doi.org/10.3174/ajnr.A8022
Urs Würtemberger
aFrom the Department of Neuroradiology (U.W., A.R., V.A., H.U., T.D.), Faculty of Medicine, Medical Center–University of Freiburg, University of Freiburg, Freiburg, Germany
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Daniel Erny
bInstitute of Neuropathology (D.E., M.D.), Faculty of Medicine, Medical Center–University of Freiburg, University of Freiburg, Freiburg, Germany
kBerta-Ottenstein-Program for Advanced Clinician Scientists (D.E.), Faculty of Medicine, University of Freiburg, Freiburg, Germany
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Alexander Rau
aFrom the Department of Neuroradiology (U.W., A.R., V.A., H.U., T.D.), Faculty of Medicine, Medical Center–University of Freiburg, University of Freiburg, Freiburg, Germany
cDepartment of Diagnostic and Interventional Radiology (A.R.), Faculty of Medicine, Medical Center–University of Freiburg, University of Freiburg, Freiburg, Germany
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Jonas A. Hosp
dDepartment of Neurology and Neurophysiology (J.A.H.), Faculty of Medicine, Medical Center–University of Freiburg, University of Freiburg, Freiburg, Germany
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Veysel Akgün
aFrom the Department of Neuroradiology (U.W., A.R., V.A., H.U., T.D.), Faculty of Medicine, Medical Center–University of Freiburg, University of Freiburg, Freiburg, Germany
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Marco Reisert
eDepartment of Medical Physics (M.R., V.G.K.), Faculty of Medicine, Medical Center–University of Freiburg, University of Freiburg, Freiburg, Germany
fDepartment of Stereotactic and Functional Neurosurgery (M.R., P.C.R.), Faculty of Medicine, Medical Center–University of Freiburg, University of Freiburg, Freiburg, Germany
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Valerij G. Kiselev
eDepartment of Medical Physics (M.R., V.G.K.), Faculty of Medicine, Medical Center–University of Freiburg, University of Freiburg, Freiburg, Germany
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Jürgen Beck
iDepartment of Neurosurgery (J.B., M.H.), Faculty of Medicine, Medical Center–University of Freiburg, University of Freiburg, Freiburg, Germany
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Sonja Jankovic
gDepartment of Radiology (S.J.), Faculty of Medicine, University Clinical Center Nis, University of Nis, Nis, Serbia
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Peter C. Reinacher
fDepartment of Stereotactic and Functional Neurosurgery (M.R., P.C.R.), Faculty of Medicine, Medical Center–University of Freiburg, University of Freiburg, Freiburg, Germany
hFraunhofer Institute for Laser Technology (P.C.R.), Aachen, Germany
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Marc Hohenhaus
iDepartment of Neurosurgery (J.B., M.H.), Faculty of Medicine, Medical Center–University of Freiburg, University of Freiburg, Freiburg, Germany
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Horst Urbach
aFrom the Department of Neuroradiology (U.W., A.R., V.A., H.U., T.D.), Faculty of Medicine, Medical Center–University of Freiburg, University of Freiburg, Freiburg, Germany
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Martin Diebold
bInstitute of Neuropathology (D.E., M.D.), Faculty of Medicine, Medical Center–University of Freiburg, University of Freiburg, Freiburg, Germany
jIMM-PACT Clinician Scientist Program (M.D.), Faculty of Medicine, University of Freiburg, Freiburg, Germany
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Theo Demerath
aFrom the Department of Neuroradiology (U.W., A.R., V.A., H.U., T.D.), Faculty of Medicine, Medical Center–University of Freiburg, University of Freiburg, Freiburg, Germany
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American Journal of Neuroradiology: 44 (11)
American Journal of Neuroradiology
Vol. 44, Issue 11
1 Nov 2023
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Cite this article
Urs Würtemberger, Daniel Erny, Alexander Rau, Jonas A. Hosp, Veysel Akgün, Marco Reisert, Valerij G. Kiselev, Jürgen Beck, Sonja Jankovic, Peter C. Reinacher, Marc Hohenhaus, Horst Urbach, Martin Diebold, Theo Demerath
Mesoscopic Assessment of Microstructure in Glioblastomas and Metastases by Merging Advanced Diffusion Imaging with Immunohistopathology
American Journal of Neuroradiology Nov 2023, 44 (11) 1262-1269; DOI: 10.3174/ajnr.A8022

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Microstructure in Glioblastomas: Advanced Imaging
Urs Würtemberger, Daniel Erny, Alexander Rau, Jonas A. Hosp, Veysel Akgün, Marco Reisert, Valerij G. Kiselev, Jürgen Beck, Sonja Jankovic, Peter C. Reinacher, Marc Hohenhaus, Horst Urbach, Martin Diebold, Theo Demerath
American Journal of Neuroradiology Nov 2023, 44 (11) 1262-1269; DOI: 10.3174/ajnr.A8022
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This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Advanced diffusion imaging reveals microstructural characteristics of primary CNS lymphoma, allowing differentiation from glioblastoma
    Urs Würtemberger, Martin Diebold, Alexander Rau, Veysel Akgün, Lucas Becker, Jürgen Beck, Peter C Reinacher, Christian A Taschner, Marco Reisert, Luca Fehrenbacher, Daniel Erny, Florian Scherer, Marc Hohenhaus, Horst Urbach, Theo Demerath
    Neuro-Oncology Advances 2024 6 1
  • Performance Comparison of Diffusion Kurtosis Imaging (DKI), Neurite Orientation Dispersion and Density Imaging (NODDI), and Diffusion Microstructure Imaging (DMI) in Predicting Adult-Type Glioma Subtype—A Pilot Study
    Leonie Zerweck, Urs Würtemberger, Uwe Klose, Marco Reisert, Vivien Richter, Thomas Nägele, Deborah Staber, Tong Han, Mi Shen, Chuanmiao Xie, Hongjie Hu, Songlin Yang, Zhijian Cao, Gunter Erb, Ulrike Ernemann, Till-Karsten Hauser
    Cancers 2025 17 5
  • A systematic review of diffusion microstructure imaging (DMI): Current and future applications in neurology research
    Sadegh Ghaderi, Sana Mohammadi, Farzad Fatehi
    Brain Disorders 2025 19

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