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Research ArticleAdult Brain

Topological Structural Brain Connectivity Alterations in Aspartylglucosaminuria: A Case-Control Study

U. Roine, A.M. Tokola, T. Autti and T. Roine
American Journal of Neuroradiology January 2023, 44 (1) 40-46; DOI: https://doi.org/10.3174/ajnr.A7745
U. Roine
aFrom the Department of Radiology (U.R., A.M.T., T.A., T.R.), HUS Medical Imaging Center
bDepartment of Pediatric Neurology (U.R.), Children’s Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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A.M. Tokola
aFrom the Department of Radiology (U.R., A.M.T., T.A., T.R.), HUS Medical Imaging Center
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T. Autti
aFrom the Department of Radiology (U.R., A.M.T., T.A., T.R.), HUS Medical Imaging Center
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T. Roine
aFrom the Department of Radiology (U.R., A.M.T., T.A., T.R.), HUS Medical Imaging Center
cDepartment of Neuroscience and Biomedical Engineering (T.R.), Aalto University School of Science, Espoo, Finland
dTurku Brain and Mind Center (T.R.), University of Turku, Turku, Finland
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References

  1. 1.↵
    1. Saarela J,
    2. von SC,
    3. Peltonen L, et al
    . A novel aspartylglucosaminuria mutation affects translocation of aspartylglucosaminidase. Hum Mutat 2004;24:350–51 doi:10.1002/humu.9276 pmid:15365992
    CrossRefPubMed
  2. 2.↵
    1. Arvio M,
    2. Mononen I
    . Aspartylglycosaminuria: a review. Orphanet J Rare Dis 2016;11:162 doi:10.1186/s13023-016-0544-6 pmid:27906067
    CrossRefPubMed
  3. 3.↵
    1. Syvänen AC,
    2. Ikonen E,
    3. Manninen T, et al
    . Convenient and quantitative determination of the frequency of a mutant allele using solid-phase minisequencing: application to aspartylglucosaminuria in Finland. Genomics 1992;12:590–95 doi:10.1016/0888-7543(92)90452-X pmid:1559710
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Goodspeed K,
    2. Feng C,
    3. Laine M, et al
    . Aspartylglucosaminuria: clinical presentation and potential therapies. J Child Neurol 2021;36:403–14 doi:10.1177/0883073820980904 pmid:33439067
    CrossRefPubMed
  5. 5.↵
    1. Arvio M,
    2. Arvio P,
    3. Hurmerinta K, et al
    . Reduction in head size in patients with aspartylglucosaminuria. Acta Neurol Scand 2005;112:335–37 doi:10.1111/j.1600-0404.2005.00492.x pmid:16218917
    CrossRefPubMed
  6. 6.↵
    1. Arvio P,
    2. Arvio M
    . Progressive nature of aspartylglucosaminuria. Acta Paediatr 2007;91:255–57 doi:10.1111/j.1651-2227.2002.tb01707.x pmid:12022293
    CrossRefPubMed
  7. 7.↵
    1. Dunder U,
    2. Valtonen P,
    3. Kelo E, et al
    . Early initiation of enzyme replacement therapy improves metabolic correction in the brain tissue of aspartylglycosaminuria mice. J Inherit Metab Dis 2010;33:611–17 doi:10.1007/s10545-010-9158-7 pmid:20607610
    CrossRefPubMed
  8. 8.↵
    1. Kelo E,
    2. Dunder U,
    3. Mononen I
    . Massive accumulation of Man2GlcNAc2-Asn in nonneuronal tissues of glycosylasparaginase-deficient mice and its removal by enzyme replacement therapy. Glycobiology 2005;15:79–85 doi:10.1093/glycob/cwh145 pmid:15342551
    CrossRefPubMedWeb of Science
  9. 9.↵
    1. Peltola M,
    2. Kyttälä A,
    3. Heinonen O, et al
    . Adenovirus-mediated gene transfer results in decreased lysosomal storage in brain and total correction in liver of aspartylglucosaminuria (AGU) mouse. Gene Ther 1998;5:1314–21 doi:10.1038/sj.gt.3300740 pmid:9930336
    CrossRefPubMedWeb of Science
  10. 10.↵
    1. Virta S,
    2. Rapola J,
    3. Jalanko A, et al
    . Use of nonviral promoters in adenovirus-mediated gene therapy: reduction of lysosomal storage in the aspartylglucosaminuria mouse. J Gene Med 2006;8:699–706 doi:10.1002/jgm.892 pmid:16518877
    CrossRefPubMed
  11. 11.↵
    1. Banning A,
    2. Gülec C,
    3. Rouvinen J, et al
    . Identification of small molecule compounds for pharmacological chaperone therapy of aspartylglucosaminuria. Sci Rep 2016;6:37583 doi:10.1038/srep37583 pmid:27876883
    CrossRefPubMed
  12. 12.↵
    1. Autti T,
    2. Joensuu R,
    3. Åberg L
    . Decreased T2 signal in the thalami may be a sign of lysosomal storage disease. Neuroradiology 2007;49:571–78 doi:10.1007/s00234-007-0220-6 pmid:17334752
    CrossRefPubMedWeb of Science
  13. 13.↵
    1. Autti T,
    2. Lönnqvist T,
    3. Joensuu R
    . Bilateral pulvinar signal intensity decrease on T2-weighted images in patients with aspartylglucosaminuria. Acta Radiol 2008;49:687–92 doi:10.1080/02841850802065000 pmid:18568562
    CrossRefPubMedWeb of Science
  14. 14.↵
    1. Tokola A,
    2. Åberg L,
    3. Autti T
    . Brain MRI findings in aspartylglucosaminuria. J Neuroradiol 2015;42:345–57 doi:10.1016/j.neurad.2015.03.003 pmid:26026191
    CrossRefPubMed
  15. 15.↵
    1. Autti T,
    2. Raininko R,
    3. Haltia M, et al
    . Aspartylglucosaminuria: radiologic course of the disease with histopathologic correlation. J Child Neurol 1997;12:369–75 doi:10.1177/088307389701200606 pmid:9309520
    CrossRefPubMedWeb of Science
  16. 16.↵
    1. Goodspeed K,
    2. Horton D,
    3. Lowden A, et al
    . A cross-sectional natural history study of aspartylglucosaminuria. JIMD Rep 2022;63:425–33 doi:10.1002/jmd2.12294 pmid:36101820
    CrossRefPubMed
  17. 17.↵
    1. Tokola A,
    2. Brandstack N,
    3. Hakkarainen A, et al
    . White matter microstructure and subcortical gray matter structure volumes in aspartylglucosaminuria; a 5-year follow-up brain MRI study of an adolescent with aspartylglucosaminuria and his healthy twin brother. JIMD Rep 2017;35:105–15 doi:10.1007/8904_2016_36 pmid:28185224
    CrossRefPubMed
  18. 18.↵
    1. Hagmann P,
    2. Cammoun L,
    3. Gigandet X, et al
    . Mapping the structural core of human cerebral cortex. PLoS Biol 2008;6:e159–93 doi:10.1371/journal.pbio.0060159 pmid:18597554
    CrossRefPubMed
  19. 19.↵
    1. Bullmore E,
    2. Sporns O
    . Complex brain networks: graph theoretical analysis of structural and functional systems. Nat Rev Neurosci 2009;10:186–98 doi:10.1038/nrn2575 pmid:19190637
    CrossRefPubMedWeb of Science
  20. 20.↵
    1. Griffa A,
    2. Baumann PS,
    3. Thiran JP, et al
    . Structural connectomics in brain diseases. Neuroimage 2013;80:515–26 doi:10.1016/j.neuroimage.2013.04.056 pmid:23623973
    CrossRefPubMed
  21. 21.↵
    1. Roine T,
    2. Jeurissen B,
    3. Perrone D, et al
    . Reproducibility and intercorrelation of graph theoretical measures in structural brain connectivity networks. Med Image Anal 2019;52:56–67 doi:10.1016/j.media.2018.10.009 pmid:30471463
    CrossRefPubMed
  22. 22.↵
    1. Lei D,
    2. Li W,
    3. Tallman MJ, et al
    . Changes in the brain structural connectome after a prospective randomized clinical trial of lithium and quetiapine treatment in youth with bipolar disorder. Neuropsychopharmacology 2021;46:1315–23 doi:10.1038/s41386-021-00989-5 pmid:33753882
    CrossRefPubMed
  23. 23.↵
    1. Hu M,
    2. Zong X,
    3. Zheng J, et al
    . Risperidone-induced topological alterations of anatomical brain network in first-episode drug-naive schizophrenia patients: a longitudinal diffusion tensor imaging study. Psychol Med 2016;46:2549–60 doi:10.1017/S0033291716001380 pmid:27338296
    CrossRefPubMed
  24. 24.↵
    1. Roine T,
    2. Roine U,
    3. Tokola A, et al
    . Topological alterations of the structural brain connectivity network in children with juvenile neuronal ceroid lipofuscinosis. AJNR Am J Neuroradiol 2019;40:2146–53 doi:10.3174/ajnr.A6306 pmid:31727742
    Abstract/FREE Full Text
  25. 25.↵
    1. Leemans A,
    2. Jones DK
    . The B-matrix must be rotated when correcting for subject motion in DTI data. Magn Reson Med 2009;61:1336–49 doi:10.1002/mrm.21890 pmid:19319973
    CrossRefPubMedWeb of Science
  26. 26.↵
    1. Leemans A,
    2. Jeurissen B,
    3. Sijbers J, et al
    . ExploreDTI: a graphical toolbox for processing, analyzing, and visualizing diffusion MR data. January 2009. In: Proceedings of the 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine, 2009;3537
  27. 27.↵
    1. Irfanoglu MO,
    2. Walker L,
    3. Sarlls J, et al
    . Effects of image distortions originating from susceptibility variations and concomitant fields on diffusion MRI tractography results. Neuroimage 2012;61:275–88 doi:10.1016/j.neuroimage.2012.02.054 pmid:22401760
    CrossRefPubMed
  28. 28.↵
    1. Jeurissen B,
    2. Leemans A,
    3. Jones DK, et al
    . Probabilistic fiber tracking using the residual bootstrap with constrained spherical deconvolution. Hum Brain Mapp 2011;32:461–79 doi:10.1002/hbm.21032 pmid:21319270
    CrossRefPubMedWeb of Science
  29. 29.↵
    1. Tournier JD,
    2. Calamante F,
    3. Connelly A
    . Robust determination of the fibre orientation distribution in diffusion MRI: non-negativity constrained super-resolved spherical deconvolution. Neuroimage 2007;35:1459–72 doi:10.1016/j.neuroimage.2007.02.016 pmid:17379540
    CrossRefPubMedWeb of Science
  30. 30.↵
    1. Destrieux C,
    2. Fischl B,
    3. Dale A, et al
    . Automatic parcellation of human cortical gyri and sulci using standard anatomical nomenclature. Neuroimage 2010;53:1–15 doi:10.1016/j.neuroimage.2010.06.010 pmid:20547229
    CrossRefPubMedWeb of Science
  31. 31.↵
    1. Fischl B
    . FreeSurfer. Neuroimage 2012;62:774–81 doi:10.1016/j.neuroimage.2012.01.021 pmid:22248573
    CrossRefPubMedWeb of Science
  32. 32.↵
    1. Rubinov M,
    2. Sporns O
    . Complex network measures of brain connectivity: uses and interpretations. Neuroimage 2010;52:1059–69 doi:10.1016/j.neuroimage.2009.10.003 pmid:19819337
    CrossRefPubMedWeb of Science
  33. 33.↵
    1. Mann HB,
    2. Whitney DR
    . On a test of whether one of two random variables is stochastically larger than the other. Ann Math Stat 1947;18:50–60 doi:10.1214/aoms/1177730491
    CrossRef
  34. 34.↵
    1. Xia M,
    2. Wang J,
    3. He Y
    . BrainNet Viewer: a network visualization tool for human brain connectomics. PLoS One 2013;8:e68910 doi:10.1371/journal.pone.0068910 pmid:23861951
    CrossRefPubMed
  35. 35.↵
    1. Tournier JD,
    2. Smith R,
    3. Raffelt D, et al
    . MRtrix3: a fast, flexible and open software framework for medical image processing and visualisation. Neuroimage 2019;202:116137 doi:10.1016/j.neuroimage.2019.116137 pmid:31473352
    CrossRefPubMed
  36. 36.↵
    1. Waskom M
    . Seaborn: statistical data visualization. J Open Source Softw. 2021;6:3021 doi:10.21105/joss.03021
    CrossRef
  37. 37.↵
    1. Hunter JD
    . Matplotlib: a 2D graphics environment. Comput Sci Eng 2007;9:90–95 doi:10.1109/MCSE.2007.55
    CrossRefPubMed
  38. 38.↵
    1. Latora V,
    2. Marchiori M
    . Efficient behavior of small-world networks. Phys Rev Lett 2001;87:198701 doi:10.1103/PhysRevLett.87.198701 pmid:11690461
    CrossRefPubMed
  39. 39.↵
    1. Watts DJ,
    2. Strogatz SH
    . Collective dynamics of “small-world” networks. Nature 1998;393:440–42 doi:10.1038/30918 pmid:9623998
    CrossRefPubMedWeb of Science
  40. 40.↵
    1. Saramäki J,
    2. Kivelä M,
    3. Onnela JP, et al
    . Generalizations of the clustering coefficient to weighted complex networks. Phys Rev E Stat Nonlin Soft Matter Phys.2007;75(2 Pt 2):027105 doi:10.1103/PhysRevE.75.027105 pmid:17358454
    CrossRefPubMed
  41. 41.↵
    1. Arstila A,
    2. Palo J,
    3. Haltia M, et al
    . Aspartylglucosaminuria I: fine structural studies on liver, kidney and brain. Acta Neuropathol 1972;20:207–16 doi:10.1007/BF00686902 pmid:5044001
    CrossRefPubMed
  42. 42.↵
    1. Haltia M,
    2. Palo J,
    3. Autio S
    . Aspartylglycosaminuria: a generalized storage disease. Acta Neuropathol 1975;31:243–55 doi:10.1007/BF00684563 pmid:1138532
    CrossRefPubMedWeb of Science
  43. 43.↵
    1. Tokola A,
    2. Laine M,
    3. Tikkanen R, et al
    . Susceptibility-weighted imaging findings in aspartylglucosaminuria. AJNR Am J Neuroradiol 2019;40:1850–54 doi:10.3174/ajnr.A6288 pmid:31649158
    Abstract/FREE Full Text
  44. 44.↵
    1. Sairanen V,
    2. Tokola A,
    3. Tikkanen R, et al
    . Statistical permutation test reveals progressive and region-specific iron accumulation in the thalami of children with aspartylglucosaminuria. Brain Sci 2020;10:677 doi:10.3390/brainsci10100677 pmid:32992453
    CrossRefPubMed
  45. 45.↵
    1. Dimov A,
    2. Patel W,
    3. Yao Y, et al
    . Iron concentration linked to structural connectivity in the subthalamic nucleus: implications for deep brain stimulation. J Neurosurg 2019 Jan 18. [Epub head of print] doi:10.3171/2018.8.JNS18531 pmid:30660115
    CrossRefPubMed
  46. 46.↵
    1. Zachariou V,
    2. Bauer CE,
    3. Seago ER, et al
    . Cortical iron disrupts functional connectivity networks supporting working memory performance in older adults. Neuroimage 2020;223:117309 doi:10.1016/j.neuroimage.2020.117309 pmid:32861788
    CrossRefPubMed
  47. 47.↵
    1. Acheson DJ,
    2. Hagoort P
    . Stimulating the brain’s language network: syntactic ambiguity resolution after TMS to the inferior frontal gyrus and middle temporal gyrus. J Cogn Neurosci 2013;25:1664–77 doi:10.1162/jocn_a_00430
    CrossRefPubMed
  48. 48.↵
    1. Binder JR,
    2. Frost JA,
    3. Hammeke TA, et al
    . Function of the left planum temporale in auditory and linguistic processing. Brain 1996;119:1239–47 doi:10.1093/brain/119.4.1239 pmid:8813286
    CrossRefPubMedWeb of Science
  49. 49.↵
    1. Keenan JP,
    2. Thangaraj V,
    3. Halpern AR, et al
    . Absolute pitch and planum temporale. Neuroimage 2001;14:1402–08 doi:10.1006/nimg.2001.0925 pmid:11707095
    CrossRefPubMedWeb of Science
  50. 50.↵
    1. Dorsaint-Pierre R,
    2. Penhune VB,
    3. Watkins KE, et al
    . Asymmetries of the planum temporale and Heschl’s gyrus: relationship to language lateralization. Brain 2006;129:1164–76 doi:10.1093/brain/awl055 pmid:16537567
    CrossRefPubMedWeb of Science
  51. 51.↵
    1. Larsen JP,
    2. Høien T,
    3. Lundberg I, et al
    . MRI evaluation of the size and symmetry of the planum temporale in adolescents with developmental dyslexia. Brain Lang 1990;39:289–301 doi:10.1016/0093-934X(90)90015-9 pmid:2224496
    CrossRefPubMedWeb of Science
  52. 52.↵
    1. Foundas AL,
    2. Bollich AM,
    3. Feldman J, et al
    . Aberrant auditory processing and atypical planum temporale in developmental stuttering. Neurology 2004;63:1640–46 doi:10.1212/01.WNL.0000142993.33158.2A pmid:15534249
    Abstract/FREE Full Text
  53. 53.↵
    1. Roine U,
    2. Roine T,
    3. Hakkarainen A, et al
    . Global and widespread local white matter abnormalities in juvenile neuronal ceroid lipofuscinosis. AJNR Am J Neuroradiol 2018;39:1349–54 doi:10.3174/ajnr.A5687 pmid:29853519
    Abstract/FREE Full Text
  54. 54.↵
    1. Tournier JD,
    2. Calamante F,
    3. Connelly A
    . Determination of the appropriate b value and number of gradient directions for high-angular-resolution diffusion-weighted imaging. NMR Biomed 2013;26:1775–86 doi:10.1002/nbm.3017 pmid:24038308
    CrossRefPubMedWeb of Science
  55. 55.↵
    1. Raffelt D,
    2. Tournier JD,
    3. Rose S, et al
    . Apparent fibre density: a novel measure for the analysis of diffusion-weighted magnetic resonance images. Neuroimage 2012;59:3976–94 doi:10.1016/j.neuroimage.2011.10.045 pmid:22036682
    CrossRefPubMed
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Cite this article
U. Roine, A.M. Tokola, T. Autti, T. Roine
Topological Structural Brain Connectivity Alterations in Aspartylglucosaminuria: A Case-Control Study
American Journal of Neuroradiology Jan 2023, 44 (1) 40-46; DOI: 10.3174/ajnr.A7745

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Brain Connectivity in Aspartylglucosaminuria
U. Roine, A.M. Tokola, T. Autti, T. Roine
American Journal of Neuroradiology Jan 2023, 44 (1) 40-46; DOI: 10.3174/ajnr.A7745
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