Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleNeurointervention

Comparison of Pipeline Embolization Device Sizing Based on Conventional 2D Measurements and Virtual Simulation Using the Sim&Size Software: An Agreement Study

J.M. Ospel, G. Gascou, V. Costalat, L. Piergallini, K.A. Blackham and D.W. Zumofen
American Journal of Neuroradiology March 2019, 40 (3) 524-530; DOI: https://doi.org/10.3174/ajnr.A5973
J.M. Ospel
aFrom the Diagnostic and Interventional Neuroradiology Section (J.M.O., K.A.B., D.W.Z.), Department of Radiology and Nuclear Medicine
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J.M. Ospel
G. Gascou
cDepartment of Neuroradiology (G.G., V.C., L.P.), Hôpital Gui de Chauliac, Centre Hospitalier Universitaire de Montpellier, University of Montpellier, Montpellier, France
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for G. Gascou
V. Costalat
cDepartment of Neuroradiology (G.G., V.C., L.P.), Hôpital Gui de Chauliac, Centre Hospitalier Universitaire de Montpellier, University of Montpellier, Montpellier, France
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for V. Costalat
L. Piergallini
cDepartment of Neuroradiology (G.G., V.C., L.P.), Hôpital Gui de Chauliac, Centre Hospitalier Universitaire de Montpellier, University of Montpellier, Montpellier, France
dPostgraduation School of Radiodiagnostics (L.P.), Università degli Studi di Milano, Milan, Italy.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for L. Piergallini
K.A. Blackham
aFrom the Diagnostic and Interventional Neuroradiology Section (J.M.O., K.A.B., D.W.Z.), Department of Radiology and Nuclear Medicine
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for K.A. Blackham
D.W. Zumofen
aFrom the Diagnostic and Interventional Neuroradiology Section (J.M.O., K.A.B., D.W.Z.), Department of Radiology and Nuclear Medicine
bDepartment of Neurosurgery (D.W.Z.), University Hospital Basel, University of Basel, Basel, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for D.W. Zumofen
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

Article Figures & Data

Figures

  • Tables
  • Fig 1.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 1.

    The Sim&Size software anticipates intraluminal PED behavior, wall apposition, and device length after implantation on the basis of preimplantation rotational angiography DICOM data. The planned microcatheter trajectory for PED delivery is indicated in blue. Anticipated wall apposition along the covered segment is color-coded from red (no apposition) to green (good apposition). Courtesy of Cindy Wehrli and Phil Häfliger from Medtronic, Switzerland.

  • Fig 2.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 2.

    Boxplots illustrating differences between manually determined presumed optimal device dimensions and computed optimal PED dimensions for PED length (A) and for PED diameter (B).

  • Fig 3.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 3.

    Bar graph illustrating differences between manually determined presumed optimal device dimensions and computed optimal PEDs. Computed optimal device diameter was larger in 31 cases, identical to the neurointerventionalists' manual selection in 22 cases, and smaller in the remaining 21 cases. Computed optimal device length was shorter in 42 cases, identical to the neurointerventionalists' manual selection in 19 cases, and longer in the remaining 13 cases.

  • Fig 4.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 4.

    Bar graph illustrating the proportion of cases in which computed PED lengths were shorter than manually determined lengths for the anterior circulation. The proportion of cases in which computed optimal PED lengths were shorter increases from proximal to distal.

Tables

  • Figures
    • View popup
    Table 1:

    Baseline characteristicsa

    Characteristics
    Sex (No.) (%)
        Male63 (85.1%)
        Female11 (14.9%)
    Patient age (mean) (SD, range) (yr)58.6 (13.3, 30–83)
    Ruptured aneurysms (No.) (%)5 (6.8%)
    Acute dissection (No.) (%)15 (20.3%)
    Location of aneurysms (No.) (%)
        Cervical ICA10 (13.5%)
        Petrous ICA13 (17.6%)
        Cavernous ICA26 (35.1%)
        Paraophthalmic ICA10 (13.5%)
        Communicating ICA1 (1.4%)
        Choroidal ICA1 (1.4%)
        Vertebrobasilar circulation3 (4.1%)
        ACA4 (5.4%)
        MCA6 (8.1%)
    Maximum aneurysm diameter (mean) (SD, range) (mm)8.8 (7.2, 2.0–40.0)
    Multi-PED constructs (No.) (%)7 (9.5%)
    Use of additional coils (No.) (%)11 (14.9%)
    • Note:—ACA indicates anterior cerebral artery.

    • ↵a Location of ICA aneurysms is provided according to the New York University classification.35 Number of patients = 74.

    • View popup
    Table 2:

    Dimensions (diameter, length) of the manually determined presumed optimal and computed optimal PEDs

    Manually DeterminedComputed Optimal
    PED diameter (mm)
        Mean (SD)3.89 (0.70)3.94 (0.69)
        Range2.5–52.5–5
        Median (IQR)4 (3.50–4.50)4 (3.25–4.50)
    PED length (mm)
        Mean (SD)16.31 (3.94)15.22 (5.21)
        Range10–3510–35
        Median (IQR)16 (14–18)14 (11.5–18)
    • Note:—IQR indicates interquartile range.

PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 40 (3)
American Journal of Neuroradiology
Vol. 40, Issue 3
1 Mar 2019
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Comparison of Pipeline Embolization Device Sizing Based on Conventional 2D Measurements and Virtual Simulation Using the Sim&Size Software: An Agreement Study
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
J.M. Ospel, G. Gascou, V. Costalat, L. Piergallini, K.A. Blackham, D.W. Zumofen
Comparison of Pipeline Embolization Device Sizing Based on Conventional 2D Measurements and Virtual Simulation Using the Sim&Size Software: An Agreement Study
American Journal of Neuroradiology Mar 2019, 40 (3) 524-530; DOI: 10.3174/ajnr.A5973

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Comparison of Pipeline Embolization Device Sizing Based on Conventional 2D Measurements and Virtual Simulation Using the Sim&Size Software: An Agreement Study
J.M. Ospel, G. Gascou, V. Costalat, L. Piergallini, K.A. Blackham, D.W. Zumofen
American Journal of Neuroradiology Mar 2019, 40 (3) 524-530; DOI: 10.3174/ajnr.A5973
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATION:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • High variability in physician estimations of flow-diverting stent deployment versus PreSize Neurovascular software simulation: a comparison study
  • Predicting flow diverter sizing using the AneuGuideTM software: a validation study
  • Comparison of Woven EndoBridge device sizing with conventional measurements and virtual simulation using the Sim&Size software: a multicenter experience
  • Current and future usefulness and potential of virtual simulation in improving outcomes and reducing complications in endovascular treatment of unruptured intracranial aneurysms
  • Review of current intracranial aneurysm flow diversion technology and clinical use
  • Virtual simulation with Sim&Size software for Pipeline Flex Embolization: evaluation of the technical and clinical impact
  • A Multicenter Pilot Study on the Clinical Utility of Computational Modeling for Flow-Diverter Treatment Planning
  • Pipeline Sizing Based on Computer Simulation
  • Crossref (14)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • A Survey on Digital Twin: Definitions, Characteristics, Applications, and Design Implications
    Barbara Rita Barricelli, Elena Casiraghi, Daniela Fogli
    IEEE Access 2019 7
  • The Role of AI, Machine Learning, and Big Data in Digital Twinning: A Systematic Literature Review, Challenges, and Opportunities
    M. Mazhar Rathore, Syed Attique Shah, Dhirendra Shukla, Elmahdi Bentafat, Spiridon Bakiras
    IEEE Access 2021 9
  • Human Digital Twin for Fitness Management
    Barbara Rita Barricelli, Elena Casiraghi, Jessica Gliozzo, Alessandro Petrini, Stefano Valtolina
    IEEE Access 2020 8
  • Review of current intracranial aneurysm flow diversion technology and clinical use
    Sudeepta Dandapat, Alan Mendez-Ruiz, Mario Martínez-Galdámez, Juan Macho, Shahram Derakhshani, Gustavo Foa Torres, Vitor M Pereira, Anil Arat, Ajay K Wakhloo, Santiago Ortega-Gutierrez
    Journal of NeuroInterventional Surgery 2021 13 1
  • Virtual simulation with Sim&Size software for Pipeline Flex Embolization: evaluation of the technical and clinical impact
    Lorenzo Piergallini, Federico Cagnazzo, Giorgio Conte, Cyril Dargazanli, Imad Derraz, Pierre-Henri Lefevre, Gregory Gascou, Daniel Mantilla, Carlos Riquelme, Alain Bonafe, Vincent Costalat
    Journal of NeuroInterventional Surgery 2020 12 10
  • Comparison of Woven EndoBridge device sizing with conventional measurements and virtual simulation using the Sim&Size software: a multicenter experience
    Federico Cagnazzo, Gaultier Marnat, Ivan Ferreira, Pierre Daube, Imad Derraz, Cyril Dargazanli, Pierre-Henri Lefevre, Gregory Gascou, Carlos Riquelme, Riccardo Morganti, Jérôme Berge, Florent Gariel, Xavier Barreau, Vincent Costalat
    Journal of NeuroInterventional Surgery 2021 13 10
  • Deployment of flow diverter devices: prediction of foreshortening and validation of the simulation in 18 clinical cases
    Robert Kellermann, Steffen Serowy, Oliver Beuing, Martin Skalej
    Neuroradiology 2019 61 11
  • Predicting flow diverter sizing using the AneuGuideTMsoftware: a validation study
    Xin Tong, Yejie Shan, Xiaochang Leng, Jigang Chen, Jens Fiehler, Adnan H Siddiqui, Xuebin Hu, Aihua Liu, Jianping Xiang
    Journal of NeuroInterventional Surgery 2023 15 1
  • Current and future usefulness and potential of virtual simulation in improving outcomes and reducing complications in endovascular treatment of unruptured intracranial aneurysms
    Johanna Maria Ospel, Nima Kashani, Arnuv Mayank, Thomas Liebig, Johannes Kaesmacher, Markus Holtmannspötter, Jai Shankar, Mohammed A Almekhlafi, Alim P Mitha, John H Wong, Mayank Goyal
    Journal of NeuroInterventional Surgery 2021 13 3
  • Rehearsals using patient-specific 3D-printed aneurysm models for simulation of endovascular embolization of complex intracranial aneurysms: 3D SIM study
    Anthony Le Bras, Fakhreddine Boustia, Kevin Janot, Estelle Le Pabic, Mathilde Ouvrard, Claire Fougerou-Leurent, Jean-Christophe Ferre, Jean-Yves Gauvrit, François Eugene
    Journal of Neuroradiology 2023 50 1

More in this TOC Section

  • Factors Associated with Major Re-Recanalization following Second Coiling for Recanalized Aneurysms: A Multicenter Experience over 20 Years during Long-Term Follow-up
  • A Key Factor Shapes LS-DAVFs EVT Outcome
  • Optimizing Voxel Size in 3D Rotational Angiography
Show more Neurointervention

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire