Amide Proton Transfer Imaging Allows Detection of Glioma Grades and Tumor Proliferation: Comparison with Ki-67 Expression and Proton MR Spectroscopy Imaging

References

1. 1.↵
   2. Louis DN,
   3. Ohgaki H,
   4. Wiestler OD, et al

   . The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 2007;114:97–109 doi:10.1007/s00401-007-0243-4 pmid:17618441

   CrossRefPubMedWeb of Science
2. 2.↵
   2. Wen PY,
   3. Kesari S

   . Malignant gliomas in adults. N Engl J Med 2008;359:492–507 doi:10.1056/NEJMra0708126 pmid:18669428

   CrossRefPubMedWeb of Science
3. 3.↵
   2. Stupp R,
   3. Mason WP,
   4. van den Bent MJ, et al

   . Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005;352:987–96 doi:10.1056/NEJMoa043330 pmid:15758009

   CrossRefPubMedWeb of Science
4. 4.↵
   2. Brat DJ,
   3. Verhaak RG, et al

   Cancer Genome Atlas Research Network, Brat DJ, Verhaak RG, et al. Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas. N Engl J Med 2015;372:2481–98 doi:10.1056/NEJMoa1402121 pmid:26061751

   CrossRefPubMed
5. 5.↵
   2. Hoshino T,
   3. Ahn D,
   4. Prados MD, et al

   . Prognostic significance of the proliferative potential of intracranial gliomas measured by bromodeoxyuridine labeling. Int J Cancer 1993;53:550–55 doi:10.1002/ijc.2910530404 pmid:8382191

   CrossRefPubMedWeb of Science
6. 6.↵
   2. Sallinen PK,
   3. Haapasalo HK,
   4. Visakorpi T, et al

   . Prognostication of astrocytoma patient survival by Ki-67 (MIB-1), PCNA, and S-phase fraction using archival paraffin-embedded samples. J Pathol 1994;174:275–82 doi:10.1002/path.1711740407 pmid:7884589

   CrossRefPubMedWeb of Science
7. 7.↵
   2. Tamiya T,
   3. Kinoshita K,
   4. Ono Y, et al

   . Proton magnetic resonance spectroscopy reflects cellular proliferative activity in astrocytomas. Neuroradiology 2000;42:333–38 doi:10.1007/s002340050894 pmid:10872152

   CrossRefPubMed
8. 8.↵
   2. Tedeschi G,
   3. Lundbom N,
   4. Raman R, et al

   . Increased choline signal coinciding with malignant degeneration of cerebral gliomas: a serial proton magnetic resonance spectroscopy imaging study. J Neurosurg 1997;87:516–24 doi:10.3171/jns.1997.87.4.0516 pmid:9322842

   CrossRefPubMedWeb of Science
9. 9.↵
   2. Moffett JR,
   3. Ross B,
   4. Arun P, et al

   . N-Acetylaspartate in the CNS: from neurodiagnostics to neurobiology. Prog Neurobiol 2007;81:89–131 doi:10.1016/j.pneurobio.2006.12.003 pmid:17275978

   CrossRefPubMedWeb of Science
10. 10.↵
    2. Stadlbauer A,
    3. Gruber S,
    4. Nimsky C, et al

    . Preoperative grading of gliomas by using metabolite quantification with high-spatial-resolution proton MR spectroscopic imaging. Radiology 2006;238:958–69 doi:10.1148/radiol.2382041896 pmid:16424238

    CrossRefPubMedWeb of Science
11. 11.↵
    2. Bulik M,
    3. Jancalek R,
    4. Vanicek J, et al

    . Potential of MR spectroscopy for assessment of glioma grading. Clin Neurol Neurosurg 2013;115:146–53 doi:10.1016/j.clineuro.2012.11.002 pmid:23237636

    CrossRefPubMed
12. 12.↵
    2. Zhou J,
    3. Lal B,
    4. Wilson DA, et al

    . Amide proton transfer (APT) contrast for imaging of brain tumors. Magn Reson Med 2003;50:1120–26 doi:10.1002/mrm.10651 pmid:14648559

    CrossRefPubMedWeb of Science
13. 13.↵
    2. Sagiyama K,
    3. Mashimo T,
    4. Togao O, et al

    . In vivo chemical exchange saturation transfer imaging allows early detection of a therapeutic response in glioblastoma. Proc Natl Acad Sci U S A 2014;111:4542–47 doi:10.1073/pnas.1323855111 pmid:24616497

    Abstract/FREE Full Text
14. 14.↵
    2. Zhou J,
    3. Tryggestad E,
    4. Wen Z, et al

    . Differentiation between glioma and radiation necrosis using molecular magnetic resonance imaging of endogenous proteins and peptides. Nat Med 2011;17:130–34 doi:10.1038/nm.2268 pmid:21170048

    CrossRefPubMed
15. 15.↵
    2. Park JE,
    3. Kim HS,
    4. Park KJ, et al

    . Pre- and posttreatment glioma: comparison of amide proton transfer imaging with MR spectroscopy for biomarkers of tumor proliferation. Radiology 2016;278:514–23 doi:10.1148/radiol.2015142979 pmid:26491847

    CrossRefPubMed
16. 16.↵
    2. Togao O,
    3. Yoshiura T,
    4. Keupp J, et al

    . Amide proton transfer imaging of adult diffuse gliomas: correlation with histopathological grades. Neuro Oncol 2014;16:441–48 doi:10.1093/neuonc/not158 pmid:24305718

    CrossRefPubMed
17. 17.↵
    2. Tee YK,
    3. Donahue MJ,
    4. Harston GW, et al

    . Quantification of amide proton transfer effect pre- and post-gadolinium contrast agent administration. J Magn Reson Imaging 2014;40:832–38 doi:10.1002/jmri.24441 pmid:24214526

    CrossRefPubMed
18. 18.↵
    2. Howe FA,
    3. Barton SJ,
    4. Cudlip SA, et al

    . Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy. Magn Reson Med 2003;49:223–32 doi:10.1002/mrm.10367 pmid:12541241

    CrossRefPubMed
19. 19.↵
    2. Maintz D,
    3. Heindel W,
    4. Kugel H, et al

    . Phosphorus-31 MR spectroscopy of normal adult human brain and brain tumours. NMR Biomed 2002;15:18–27 doi:10.1002/nbm.735 pmid:11840549

    CrossRefPubMedWeb of Science
20. 20.↵
    2. Ha DH,
    3. Choi S,
    4. Oh JY, et al

    . Application of 31P MR spectroscopy to the brain tumors. Korean J Radiol 2013;14:477–86 doi:10.3348/kjr.2013.14.3.477 pmid:23690717

    CrossRefPubMedWeb of Science
21. 21.↵
    2. Howe FA,
    3. Opstad KS

    . 1H MR spectroscopy of brain tumours and masses. NMR Biomed 2003;16:123–31 doi:10.1002/nbm.822 pmid:12884355

    CrossRefPubMed
22. 22.↵
    2. Nelson SJ

    . Multivoxel magnetic resonance spectroscopy of brain tumors. Mol Cancer Ther 2003;2:497–507 pmid:12748312

    Abstract/FREE Full Text
23. 23.↵
    2. Stadlbauer A,
    3. Hammen T,
    4. Buchfelder M, et al

    . Differences in metabolism of fiber tract alterations in gliomas: a combined fiber density mapping and magnetic resonance spectroscopic imaging study. Neurosurgery 2012;71:454–63 doi:10.1227/NEU.0b013e318258e332 pmid:22517254

    CrossRefPubMed
24. 24.↵
    2. Zeng QS,
    3. Li CF,
    4. Liu H, et al

    . Distinction between recurrent glioma and radiation injury using magnetic resonance spectroscopy in combination with diffusion-weighted imaging. Int J Radiat Oncol Biol Phys 2007;68:151–58 doi:10.1016/j.ijrobp.2006.12.001 pmid:17289287

    CrossRefPubMed
25. 25.↵
    2. Zhou J,
    3. Blakeley JO,
    4. Hua J, et al

    . Practical data acquisition method for human brain tumor amide proton transfer (APT) imaging. Magn Reson Med 2008;60:842–49 doi:10.1002/mrm.21712 pmid:18816868

    CrossRefPubMed
26. 26.↵
    2. Zhou J,
    3. Zhu H,
    4. Lim M, et al

    . Three-dimensional amide proton transfer MR imaging of gliomas: initial experience and comparison with gadolinium enhancement. J Magn Reson Imaging 2013;38:1119–28 doi:10.1002/jmri.24067 pmid:23440878

    CrossRefPubMed
27. 27.↵
    2. Sakata A,
    3. Okada T,
    4. Yamamoto A, et al

    . Grading glial tumors with amide proton transfer MR imaging: different analytical approaches. J Neurooncol 2015;122:339–48 doi:10.1007/s11060-014-1715-8 pmid:25559689

    CrossRefPubMed