Article Figures & Data
Figures
- Fig 1.
Ratios of mean values of hemodynamic and geometric variables of ruptured over unruptured mirror aneurysms. Statistically significant differences (P < .05) are indicated with an asterisk, and marginally significant differences (P < .05 on 1-sided test), with a dagger. LSA indicates percentage area under low WSS; SCI, shear concentration index; Vmax, maximum flow velocity; Q, aneurysm flow rate; ICI, inflow concentration index; norm, normal; Asize, aneurysm maximum size; Nsize, neck maximum size; AR, aspect ratio (≤ depth/neck size); VO, mean aneurysm vorticity; SR, shear rates; VE, mean aneurysm velocity.
- Fig 2.
Ratios of mean values of hemodynamic and geometric variables of ruptured over unruptured ipsilateral aneurysms. Error bars indicate variability of the mean ratios over 100 random selections of ruptured–unruptured multiple aneurysm pairs. Statistically significant differences (Pmax < .05) are indicated with an asterisk, and marginally significant differences (mean P = .05 but Pmax > .05), with a dagger. LSA indicates percentage area under low WSS; SCI, shear concentration index; Vmax, maximum flow velocity; Q, aneurysm flow rate; ICI, inflow concentration index; norm, normal; Asize, aneurysm maximum size; Nsize, neck maximum size; AR, aspect ratio (≤depth/neck size); VO, mean aneurysm vorticity; SR, shear rates; VE, mean aneurysm velocity.
- Fig 3.
Example of ruptured (right posterior communicating artery aneurysm, left column) and unruptured (right posterior communicating artery aneurysm, right column) mirror aneurysm pairs. The Left panel shows from top to bottom: 3D rotational angiography images, WSS distributions, and OSI distributions. The right panel shows from top to bottom: inflow jets, flow patterns, and vortex core lines at 4 times during the cardiac cycle.
- Fig 4.
Example of ruptured (anterior communicating artery aneurysm fed from the left A1) and unruptured (left posterior communicating artery aneurysm) multiple ipsilateral aneurysms. The left panel shows from top to bottom: 3D rotational angiography image, WSS distributions, and OSI distributions. The right panel shows from top to bottom: inflow jets, flow patterns, and vortex core lines at 4 time instances during the cardiac cycle.
Tables
Hemodynamic and geometric characteristics of ruptured and unruptured mirror and multiple ipsilateral aneurysmsa
Variable Mirror Aneurysms Ipsilateral Aneurysms Unruptured Ruptured P Value Unruptured Ruptured P mean P max WSSmin 0.6 ± 0.9 0.4 ± 0.6 .24 1.3 ± 2.0 0.4 ± 0.8 <.001b <.001b WSSmax 285.3 ± 216.1 269.5 ± 183.1 1.00 269.6 ± 324.5 784.9 ± 2730.4 .006b .05b WSSmean 28.1 ± 26.8 22.3 ± 18.6 .49 29.3 ± 35.5 27.1 ± 36.8 .28 .81 WSSnorm 0.53 ± 0.40 0.44 ± 0.26 .30 0.60 ± 0.39 0.50 ± 0.32 .12 .43 SCI 5.48 ± 10.87 5.54 ± 4.53 .21 3.30 ± 3.95 6.74 ± 7.20 <.001b <.001b LSA 51.6 ± 33.0 50.9 ± 33.4 .81 48.7 ± 32.4 49.6 ± 32.0 .72 1.00 OSImax 0.243 ± 0.123 0.334 ± 0.115 .008b 0.181 ± 0.134 0.332 ± 0.103 <.001b <.001b OSImean 0.012 ± 0.010 0.014 ± 0.010 .55 0.009 ± 0.011 0.014 ± 0.010 .005b .06 Q 0.80 ± 1.15 0.72 ± 0.85 .79 0.23 ± 0.29 0.70 ± 0.62 <.001b <.001b ICI 0.72 ± 0.89 0.82 ± 0.80 .66 0.24 ± 0.43 0.68 ± 0.57 <.001b <.001b Vmax 82.3 ± 62.5 80.8 ± 44.4 .88 61.9 ± 63.1 98.2 ± 81.0 <.001b <.001b VE 11.8 ± 10.1 10.1 ± 6.8 .77 9.1 ± 8.9 10.9 ± 9.4 .29 .70 SR 259.6 ± 192.3 229.2 ± 159.8 .68 339.6 ± 305.0 246.1 ± 236.4 .03b .18 VO 363.1 ± 284.9 319.1 ± 225.8 .70 445.7 ± 421.7 346.1 ± 345.6 .09 .38 CORELEN 1.481 ± 2.014 2.501 ± 3.159 .17 0.376 ± 0.557 2.226 ± 2.144 <.001b <.001b PODENT 0.167 ± 0.136 0.175 ± 0.074 .33 0.137 ± 0.121 0.192 ± 0.127 .009b .08 Asize 0.594 ± 0.331 0.713 ± 0.361 .14 0.365 ± 0.185 0.726 ± 0.282 <.001b <.001b Nsize 0.412 ± 0.185 0.422 ± 0.147 .75 0.306 ± 0.127 0.423 ± 0.136 <.001b <.001b AR 0.956 ± 0.755 1.176 ± 0.551 .06 0.669 ± 0.408 1.198 ± 0.609 <.001b <.001b Distality – – – 0.444 ± 0.345 0.612 ± 0.321 <.008b .04b Note:—LSA indicates percentage area under low WSS; SCI, shear concentration index; Vmax, maximum flow velocity; Q, aneurysm flow rate; ICI, inflow concentration index; norm, normalized; Asize, aneurysm maximum size; Nsize, neck maximum size; AR, aspect ratio (≤depth/neck size); VO, mean aneurysm vorticity; SR, shear rates; VE, mean aneurysm velocity; Distality, coordinate of vessel segment along the arterial tree.
↵a Values are given as mean ± SD. P values correspond to univariate paired Wilcoxon rank sum tests. For ipsilateral aneurysms, mean and maximum P values of 100 randomly selected ruptured–unruptured pairs are given.
↵b Significant difference (P < .05).
