Clinical Impact of Ventilation Duration in Patients with Stroke Undergoing Interventional Treatment under General Anesthesia: The Shorter the Better?

Article Figures & Data

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Fig 1.
Boxplots illustrating the association between outcome measures and ventilation times. Clinical measures (mRS and death) as assessed after 90 days.
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Fig 2.
Cox regression showing the cumulative hazard for pneumonia during hospitalization and unfavorable clinical outcome (mRS ≥3 and death assessed after 90 days), depending on ventilation duration.
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Fig 3.
Odds ratios for pneumonia during hospitalization and unfavorable clinical outcome (mRS ≥3 and death assessed after 90 days), depending on whether extubation was performed immediately after the procedure or within time windows of 6, 12, 18.5, 24, 48, 72, 96 hours, and 1 week.

Univariate analysis (Pearson χ² and Student t tests) of factors influencing pneumonia rates and clinical outcome

Characteristics	Pneumonia (P Value)	mRS >2 (P Value)	Death (P Value)
Hypertension	.919	.565	.195
Diabetes	.364	.001^{^a}	.001^{^a}
Fat metabolism disorder	.061	.834	.542
Adiposity	.069	.775	.921
Nicotine	.645	.001^{^a}	.239
Alcohol	.145	.354	.283
Cardiovascular disease	.709	.708	.783
Atrial fibrillation	.404	.215	.667
Prior stroke	.727	.078	.070
Age older than 70 yr	.260	<.001^{^a}	.079
Antiplatelet medication	.170	.599	.761
Anticoagulant medication	.206	.755	.815
Onset to recanalization	.268	.630	.884
TICI ≥2b	.947	.237	.059
>1/3 MCA territory	.004^{^a}	<.001^{^a}	<.001^{^a}
Pneumonia	–	.001^{^a}	.274
Intracerebral hemorrhage	.450	.170	.092