High-Resolution 7T MR Imaging of the Motor Cortex in Amyotrophic Lateral Sclerosis

References

1. 1.↵
   2. Strong M,
   3. Rosenfeld J

   . Amyotrophic lateral sclerosis: a review of current concepts. Amyotroph Lateral Scler Other Motor Neuron Disord 2003;4:136–43 doi:10.1080/14660820310011250 pmid:13129799

   CrossRefPubMed
2. 2.↵
   2. Claus D,
   3. Brunhölzl C,
   4. Kerling FP, et al

   . Transcranial magnetic stimulation as a diagnostic and prognostic test in amyotrophic lateral sclerosis. J Neurol Sci 1995;129(suppl):30–34 doi:10.1016/0022-510X(95)00056-8 pmid:7595614

   CrossRefPubMed
3. 3.↵
   2. de Carvalho M,
   3. Dengler R,
   4. Eisen A, et al

   . Electrodiagnostic criteria for diagnosis of ALS. Clin Neurophysiol 2008;119:497–503 doi:10.1016/j.clinph.2007.09.143 pmid:18164242

   CrossRefPubMedWeb of Science
4. 4.↵
   2. Vucic S,
   3. Kiernan MC

   . Utility of transcranial magnetic stimulation in delineating amyotrophic lateral sclerosis pathophysiology. Handb Clin Neurol 2013;116:561–75 doi:10.1016/B978-0-444-53497-2.00045-0 pmid:24112924

   CrossRefPubMed
5. 5.↵
   2. Chiò A,
   3. Pagani M,
   4. Agosta F, et al

   . Neuroimaging in amyotrophic lateral sclerosis: insights into structural and functional changes. Lancet Neurol 2014;13:1228–40 doi:10.1016/S1474-4422(14)70167-X pmid:25453462

   CrossRefPubMed
6. 6.↵
   2. Ince PG,
   3. Evans J,
   4. Knopp M, et al

   . Corticospinal tract degeneration in the progressive muscular atrophy variant of ALS. Neurology 2003;60:1252–58 doi:10.1212/01.WNL.0000058901.75728.4E pmid:12707426

   Abstract/FREE Full Text
7. 7.↵
   2. Philips T,
   3. Robberecht W

   . Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease. Lancet Neurol 2011;10:253–63 doi:10.1016/S1474-4422(11)70015-1 pmid:21349440

   CrossRefPubMedWeb of Science
8. 8.↵
   2. Turner MR,
   3. Cagnin A,
   4. Turkheimer FE, et al

   . Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study. Neurobiol Dis 2004;15:601–09 doi:10.1016/j.nbd.2003.12.012 pmid:15056468

   CrossRefPubMedWeb of Science
9. 9.↵
   2. Kwan JY,
   3. Jeong SY,
   4. Van Gelderen P, et al

   . Iron accumulation in deep cortical layers accounts for MRI signal abnormalities in ALS: correlating 7 Tesla MRI and pathology. PLoS One 2012;7:e35241 doi:10.1371/journal.pone.0035241 pmid:22529995

   CrossRefPubMed
10. 10.↵
    2. Haacke EM,
    3. Mittal S,
    4. Wu Z, et al

    . Susceptibility-weighted imaging: technical aspects and clinical applications, part 1. AJNR Am J Neuroradiol 2009;30:19–30 pmid:19039041

    Abstract/FREE Full Text
11. 11.↵
    1. Haacke EM,
    2. Reichenbach JR

    2. Liu M,
    3. Habib C,
    4. Miao Y, et al

    . Measuring iron content with phase. In: Haacke EM, Reichenbach JR, eds. Susceptibility Weighted Imaging in MRI: Basic Concept and Clinical Applications. 10th ed. Hoboken: John Wiley & Sons; 2011:369–401
12. 12.↵
    2. Duyn JH

    . High-field MRI of brain iron. Methods Mol Biol 2011;711:239–49 doi:10.1007/978-1-61737-992-5_11 pmid:21279605

    CrossRefPubMedWeb of Science
13. 13.↵
    2. Adachi Y,
    3. Sato N,
    4. Saito Y, et al

    . Usefulness of SWI for the detection of iron in the motor cortex in amyotrophic lateral sclerosis. J Neuroimaging 2015;25:443–51 doi:10.1111/jon.12127 pmid:24888543

    CrossRefPubMed
14. 14.↵
    1. Geyer S,
    2. Turner R

    2. Fischl B

    . Estimating the location of Brodmann areas from cortical folding patterns using histology and ex vivo MRI. In: Geyer S, Turner R, eds. Microstructural Parcellation of the Human Cerebral Cortex: From Brodmann's Post-Mortem Map to in Vivo Mapping with High-Field Magnetic Resonance Imaging. Berlin: Springer-Verlag; 2013:129–56
15. 15.↵
    2. Brooks BR,
    3. Miller RG,
    4. Swash M, et al

    ; World Federation of Neurology Research Group on Motor Neuron Disease. El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 2000;1:293–99 doi:10.1080/146608200300079536 pmid:11464847

    CrossRefPubMedWeb of Science
16. 16.↵
    2. Folstein MF,
    3. Folstein SE,
    4. McHugh PR

    . “Mini-mental state”: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189–98 doi:10.1016/0022-3956(75)90026-6 pmid:1202204

    CrossRefPubMedWeb of Science
17. 17.↵
    2. Appollonio I,
    3. Leone M,
    4. Isella V, et al

    . The frontal assessment battery (FAB): normative values in an Italian population sample. Neurol Sci 2005;26:108–16 doi:10.1007/s10072-005-0443-4 pmid:15995827

    CrossRefPubMed
18. 18.↵
    2. Siciliano G,
    3. Piazza S,
    4. Carlesi C, et al

    . Antioxidant capacity and protein oxidation in cerebrospinal fluid of amyotrophic lateral sclerosis. J Neurol 2007;254:575–80 doi:10.1007/s00415-006-0301-1 pmid:17426914

    CrossRefPubMed
19. 19.↵
    2. Cedarbaum JM,
    3. Stambler N,
    4. Malta E, et al

    . The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function: BDNF ALS Study Group (Phase III). J Neurol Sci 1999;169:13–21 doi:10.1016/S0022-510X(99)00210-5 pmid:10540002

    CrossRefPubMedWeb of Science
20. 20.↵
    2. Florence JM,
    3. Pandya S,
    4. King WM, et al

    . Intrarater reliability of manual muscle test (Medical Research Council scale) grades in Duchenne's muscular dystrophy. Phys Ther 1992;72:115–22; discussion 122–26 pmid:1549632

    Abstract/FREE Full Text
21. 21.↵
    2. Ashworth B

    . Preliminary trial of carisoprodol in multiple sclerosis. Practitioner 1964;192:540–42 pmid:14143329

    PubMedWeb of Science
22. 22.↵
    2. Woo JH,
    3. Wang S,
    4. Melhem ER, et al

    . Linear associations between clinically assessed upper motor neuron disease and diffusion tensor imaging metrics in amyotrophic lateral sclerosis. PLoS One 2014;9:e105753 doi:10.1371/journal.pone.0105753 pmid:25144708

    CrossRefPubMed
23. 23.↵
    2. Walhout R,
    3. Westeneng HJ,
    4. Verstraete E, et al

    . Cortical thickness in ALS: towards a marker for upper motor neuron involvement. J Neurol Neurosurg Psychiatry 2015;86:288–94 doi:10.1136/jnnp-2013-306839 pmid:25121571

    Abstract/FREE Full Text
24. 24.↵
    2. Yousry TA,
    3. Schmid UD,
    4. Alkadhi H, et al

    . Localization of the motor hand area to a knob on the precentral gyrus: a new landmark. Brain 1997;120:141–57 doi:10.1093/brain/120.1.141 pmid:9055804

    Abstract/FREE Full Text
25. 25.↵
    1. Mai JK,
    2. Paxinos G

    2. Zilles K,
    3. Amunts K

    . Architecture of the cerebral cortex. In: Mai JK, Paxinos G, eds. The Human Nervous System. 3rd ed. London: Elsevier; 2012:836–95
26. 26.↵
    2. Duyn JH,
    3. van Gelderen P,
    4. Li TQ, et al

    . High-field MRI of brain cortical substructure based on signal phase. Proc Natl Acad Sci U S A 2007;104:11796–801 doi:10.1073/pnas.0610821104 pmid:17586684

    Abstract/FREE Full Text
27. 27.↵
    2. Geyer S,
    3. Weiss M,
    4. Reimann K, et al

    . Microstructural parcellation of the human cerebral cortex: from Brodmann's post-mortem map to in vivo mapping with high-field magnetic resonance imaging. Front Hum Neurosci 2011;5:19 doi:10.3389/fnhum.2011.00019 pmid:21373360

    CrossRefPubMed
28. 28.↵
    2. Geyer S,
    3. Turner R

    . Microstructural Parcellation of the Human Cerebral Cortex: From Brodmann's Post-Mortem Map to in Vivo Mapping with High-Field Magnetic Resonance Imaging. Berlin: Springer-Verlag; 2013
29. 29.↵
    2. Verstraete E,
    3. Veldink JH,
    4. Hendrikse J, et al

    . Structural MRI reveals cortical thinning in amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 2012;83:383–88 doi:10.1136/jnnp-2011-300909 pmid:21965521

    Abstract/FREE Full Text
30. 30.↵
    2. Ignjatović A,
    3. Stević Z,
    4. Lavrnić S, et al

    . Brain iron MRI: a biomarker for amyotrophic lateral sclerosis. J Magn Reson Imaging 2013;38:1472–79 doi:10.1002/jmri.24121 pmid:23564606

    CrossRefPubMed
31. 31.↵
    2. Penfield W,
    3. Rasmussen T

    . The Cerebral Cortex of Man: A Clinical Study of Localization of Function. New York: Macmillan; 1950
32. 32.↵
    2. Cohen-Adad J,
    3. Polimeni JR,
    4. Helmer KG, et al

    . T₂* mapping and B₀ orientation-dependence at 7 T reveal cyto- and myeloarchitecture organization of the human cortex. Neuroimage 2012;60:1006–14 doi:10.1016/j.neuroimage.2012.01.053 pmid:22270354

    CrossRefPubMed
33. 33.↵
    2. Fukunaga M,
    3. Li TQ,
    4. van Gelderen P, et al

    . Layer-specific variation of iron content in cerebral cortex as a source of MRI contrast. Proc Natl Acad Sci U S A 2010;107:3834–39 doi:10.1073/pnas.0911177107

    Abstract/FREE Full Text
34. 34.↵
    1. Geyer S,
    2. Turner R

    2. Turner R

    . MRI methods for in-vivo cortical parcellation. In: Geyer S, Turner R, eds. Microstructural Parcellation of the Human Cerebral Cortex: From Brodmann's Post-Mortem Map to in Vivo Mapping with High-Field Magnetic Resonance Imaging. Berlin: Springer-Verlag; 2013:197–220
35. 35.↵
    2. Brodmann K

    . Vergleichende Lokalisationslehre der Grosshirnrinde. Leipzig: Barth; 1909
36. 36.↵
    2. Brodmann K

    . Beiträge zur histologischen Lokalisation der Grosshirnrinde: Erste Mitteilung—Die Regio Rolandica. J Psychol Neurol 1903;2:79–107
37. 37.↵
    2. Oba H,
    3. Araki T,
    4. Ohtomo K, et al

    . Amyotrophic lateral sclerosis: T2 shortening in motor cortex at MR imaging. Radiology 1993;189:843–46 doi:10.1148/radiology.189.3.8234713 pmid:8234713

    CrossRefPubMedWeb of Science
38. 38.↵
    2. Gowing G,
    3. Philips T,
    4. Van Wijmeersch B, et al

    . Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase. J Neurosci 2008;28:10234–44 doi:10.1523/JNEUROSCI.3494-08.2008 pmid:18842883

    Abstract/FREE Full Text
39. 39.↵
    2. Corcia P,
    3. Tauber C,
    4. Vercoullie J, et al

    . Molecular imaging of microglial activation in amyotrophic lateral sclerosis. PLoS One 2012;7:e52941 doi:10.1371/journal.pone.0052941 pmid:23300829

    CrossRefPubMed
40. 40.↵
    2. Agosta F,
    3. Pagani E,
    4. Rocca MA, et al

    . Voxel-based morphometry study of brain volumetry and diffusivity in amyotrophic lateral sclerosis patients with mild disability. Hum Brain Mapp 2007;28:1430–38 doi:10.1002/hbm.20364 pmid:17370339

    CrossRefPubMedWeb of Science
41. 41.↵
    2. Mezzapesa DM,
    3. Ceccarelli A,
    4. Dicuonzo F, et al

    . Whole-brain and regional brain atrophy in amyotrophic lateral sclerosis. AJNR Am J Neuroradiol 2007;28:255–59 pmid:17296989

    Abstract/FREE Full Text
42. 42.↵
    2. Cosottini M,
    3. Pesaresi I,
    4. Piazza S, et al

    . Structural and functional evaluation of cortical motor areas in amyotrophic lateral sclerosis. Exp Neurol 2012;234:169–80 doi:10.1016/j.expneurol.2011.12.024 pmid:22226599

    CrossRefPubMed
43. 43.↵
    2. Bede P,
    3. Bokde A,
    4. Elamin M, et al

    . Grey matter correlates of clinical variables in amyotrophic lateral sclerosis (ALS): a neuroimaging study of ALS motor phenotype heterogeneity and cortical focality. J Neurol Neurosurg Psychiatry 2013;84:766–73 doi:10.1136/jnnp-2012-302674 pmid:23085933

    Abstract/FREE Full Text
44. 44.↵
    2. Foerster BR,
    3. Pomper MG,
    4. Callaghan BC, et al

    . An imbalance between excitatory and inhibitory neurotransmitters in amyotrophic lateral sclerosis revealed by use of 3-T proton magnetic resonance spectroscopy. JAMA Neurol 2013;70:1009–16 doi:10.1001/jamaneurol.2013.234 pmid:23797905

    CrossRefPubMed
45. 45.↵
    2. Goodin DS,
    3. Rowley HA,
    4. Olney RK

    . Magnetic resonance imaging in amyotrophic lateral sclerosis. Ann Neurol 1988;23:418–20 doi:10.1002/ana.410230424 pmid:3382182

    CrossRefPubMedWeb of Science
46. 46.↵
    2. Ishikawa K,
    3. Nagura H,
    4. Yokota T, et al

    . Signal loss in the motor cortex on magnetic resonance images in amyotrophic lateral sclerosis. Ann Neurol 1993;33:218–22 doi:10.1002/ana.410330214 pmid:8434885

    CrossRefPubMed
47. 47.↵
    2. Cheung G,
    3. Gawel MJ,
    4. Cooper PW, et al

    . Amyotrophic lateral sclerosis: correlation of clinical and MR imaging findings. Radiology 1995;194:263–70 doi:10.1148/radiology.194.1.7997565 pmid:7997565

    CrossRefPubMedWeb of Science
48. 48.↵
    2. Thorpe JW,
    3. Moseley IF,
    4. Hawkes CH, et al

    . Brain and spinal cord MRI in motor neuron disease. J Neurol Neurosurg Psychiatry 1996;61:314–17 doi:10.1136/jnnp.61.3.314 pmid:8795607

    Abstract/FREE Full Text
49. 49.↵
    2. Hecht MJ,
    3. Fellner F,
    4. Fellner C, et al

    . Hyperintense and hypointense MRI signals of the precentral gyrus and corticospinal tract in ALS: a follow-up examination including FLAIR images. J Neurol Sci 2002;199:59–65 doi:10.1016/S0022-510X(02)00104-1 pmid:12084444

    CrossRefPubMed
50. 50.↵
    2. Cosottini M,
    3. Cecchi P,
    4. Piazza S, et al

    . Mapping cortical degeneration in ALS with magnetization transfer ratio and voxel-based morphometry. PLoS One 2013;8:e68279 doi:10.1371/journal.pone.0068279 pmid:23874570

    CrossRefPubMed
51. 51.↵
    2. Yokota T,
    3. Yoshino A,
    4. Inaba A, et al

    . Double cortical stimulation in amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 1996;61:596–600 doi:10.1136/jnnp.61.6.596 pmid:8971106

    Abstract/FREE Full Text
52. 52.↵
    2. Hall ED,
    3. Oostveen JA,
    4. Gurney ME

    . Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS. Glia 1998;23:249–56 doi:10.1002/(SICI)1098-1136(199807)23:3<249::AID-GLIA7>3.0.CO;2-# pmid:9633809

    CrossRefPubMedWeb of Science
53. 53.↵
    2. Boillée S,
    3. Yamanaka K,
    4. Lobsiger CS, et al

    . Onset and progression in inherited ALS determined by motor neurons and microglia. Science 2006;312:1389–92 doi:10.1126/science.1123511 pmid:16741123

    Abstract/FREE Full Text
54. 54.↵
    2. Mitchell RM,
    3. Freeman WM,
    4. Randazzo WT, et al

    . A CSF biomarker panel for identification of patients with amyotrophic lateral sclerosis. Neurology 2009;72:14–19 doi:10.1212/01.wnl.0000333251.36681.a5 pmid:18987350

    Abstract/FREE Full Text
55. 55.↵
    2. Foerster BR,
    3. Welsh RC,
    4. Feldman EL

    . 25 years of neuroimaging in amyotrophic lateral sclerosis. Nat Rev Neurol 2013;9:513–24 doi:10.1038/nrneurol.2013.153 pmid:23917850

    CrossRefPubMed
56. 56.↵
    2. Fatterpekar GM,
    3. Naidich TP,
    4. Delman BN, et al

    . Cytoarchitecture of the human cerebral cortex: MR microscopy of excised specimens at 9.4 Tesla. AJNR Am J Neuroradiol 2002;23:1313–21 pmid:12223371

    Abstract/FREE Full Text
57. 57.↵
    2. Meyer J,
    3. Roychowdhury S,
    4. Russell EJ, et al

    . Location of the central sulcus via cortical thickness of the precentral and postcentral gyri on MR. AJNR Am J Neuroradiol 1996;17:1699–706 pmid:8896626

    Abstract
58. 58.↵
    2. Glasser MF,
    3. Van Essen DC

    . Mapping human cortical areas in vivo based on myelin content as revealed by T1- and T2-weighted MRI. J Neurosci 2011;31:11597–616 doi:10.1523/JNEUROSCI.2180-11.2011 pmid:21832190

    Abstract/FREE Full Text
59. 59.↵
    2. Vogt O

    . Die myeloarchitektonische Felderung des Menschlichen Stirnhirns. J Psychol Neurol 1910;15:221–32
60. 60.↵
    1. Rehwald E

    2. Braitenberg V

    . Die Gliederung der Stirnhirnrinde auf Grund ihres Markfaserbaus (Myeloarchitektonik). In: Rehwald E, ed. Das Hirntrauma. Stuttgart: Thieme; 1956:183–203