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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleSpine

MR Myelography for Identification of Spinal CSF Leak in Spontaneous Intracranial Hypotension

J.L. Chazen, J.F. Talbott, J.E. Lantos and W.P. Dillon
American Journal of Neuroradiology October 2014, 35 (10) 2007-2012; DOI: https://doi.org/10.3174/ajnr.A3975
J.L. Chazen
aFrom the Department of Radiology (J.L.C., J.E.L.), Weill Cornell Medical Center, New York, New York
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J.F. Talbott
bDepartment of Radiology (J.F.T.), San Francisco General Hospital, San Francisco, California
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J.E. Lantos
aFrom the Department of Radiology (J.L.C., J.E.L.), Weill Cornell Medical Center, New York, New York
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W.P. Dillon
cDepartment of Radiology and Biomedical Imaging (W.P.D.), University of California, San Francisco, San Francisco, California.
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  • Fig 1.
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    Fig 1.

    Bar graph illustrating the rate of leak detection by CTM and MRM. A statistically significant difference was observed between CTM and MRM by a 2-tailed paired t test (P = .011).

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    Fig 2.

    Patient 4. A 52-year-old former fire fighter with a 1-year history of postural headaches. Axial CTM (A and C) and axial T1 fat-suppressed images from MRM (B and D) following intrathecal administration of iodinated contrast and gadolinium. Multiple spinal diverticula are seen along with an extradural contrast collection (arrows, B) not evident on a concurrent CTM examination.

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    Fig 3.

    Patient 2. A 62-year-old man with headache and recurrent subdural hemorrhage following evacuation, found to have imaging findings of SIH. Axial CTM (A) and MRM (B) images at the T9–T10 level. Spinal diverticula are evident on both examinations. The MRM demonstrates an extra-arachnoid contrast collection and ill-defined increased T1 signal surrounding the enlarged right spinal diverticula. Subsequent CT performed for epidural blood patch planning with a localization grid in place (C) shows the spinal diverticula; the extra-arachnoid contrast collection is not evident. The patient reported symptomatic relief following directed blood patch and was without headache as of the 2-month follow-up note.

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    Fig 4.

    Patient 7. A 55-year-old man with a history of lethargy, fatigue, and hearing loss. Axial CTM (A and C) and axial MRM (B and D) images. CT shows bilateral spinal diverticula. MR image demonstrates prominent contrast leakage from the right-sided T5–T6 (B) and left T10–T11 (D) diverticula, with gadolinium extending into the adjacent paraspinal musculature. The patient underwent targeted epidural blood patches of both leaking spinal diverticula.

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    Fig 5.

    Patient 8. A 55-year-old man with postural headache and low CSF pressure on lumbar puncture. Axial CTM (A), axial MRM (B), and coronal MRM (C) images. Coronal MRM shows multiple spinal diverticula. However, only the right T7–T8 spinal diverticula, seen on the CTM (A), shows evidence of contrast leakage on axial MRM (B), evident by ill-defined T1 shortening surrounding the cyst. This lesion was treated with directed epidural blood patch with symptomatic improvement for 5 years following treatment.

Tables

  • Figures
  • Patients with CSF leak detected on CTM or MRMa

    Patient No.Age (yr)SexOpening Pressure (cm H2O)Leak Detected on CTMLeak Detected on MR MyelogramTime Difference (h:min)Extent of Extra-Arachnoid ContrastSame-Day Blood PatchSuspected CSF Leak Etiology
    166Female5NoYes0:37T6–T12NoUnclear; spinal diverticula C6–C7 through L2–L3
    262Male7NoYes1:14T9–L1YesBilateral T9–T10 spinal diverticula
    327Male10YesYes0:55L2–L5NoDural ectasia; marfanoid features
    452Male7NoYes1:14T6–T12YesBilateral T9–T10 and left T11–T12 spinal diverticula
    532Female0NoYes0:29C3–L1NoNo source of leak detected; T2–T3 leak seen on subsequent fluoroscopic subtraction myelogram
    637Female6YesYes5:14T10–L1YesT11–T12 disk osteophyte; blood patch performed before MRM
    755Male8NoYes0:49T5–T6 and T9–T10NoRight T5–T6 and left T9–T10 spinal diverticula
    855Male6NoYes0:12T7–T8YesRight T7–T8 spinal diverticula
    958Female0YesYes0:46C7–T4NoT1–T2 secondary to disk protrusion and dural tear
    • ↵a The time difference reflects the time stamp difference between CTM acquisition and the beginning of MRM. A same-day blood patch was performed when logistically possible and a clear source of leak was identified.

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American Journal of Neuroradiology: 35 (10)
American Journal of Neuroradiology
Vol. 35, Issue 10
1 Oct 2014
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Cite this article
J.L. Chazen, J.F. Talbott, J.E. Lantos, W.P. Dillon
MR Myelography for Identification of Spinal CSF Leak in Spontaneous Intracranial Hypotension
American Journal of Neuroradiology Oct 2014, 35 (10) 2007-2012; DOI: 10.3174/ajnr.A3975

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MR Myelography for Identification of Spinal CSF Leak in Spontaneous Intracranial Hypotension
J.L. Chazen, J.F. Talbott, J.E. Lantos, W.P. Dillon
American Journal of Neuroradiology Oct 2014, 35 (10) 2007-2012; DOI: 10.3174/ajnr.A3975
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