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Research ArticleBrain

Brain Tissue Oxygen Monitoring to Assess Reperfusion after Intra-Arterial Treatment of Aneurysmal Subarachnoid Hemorrhage−Induced Cerebral Vasospasm: A Retrospective Study

E.M. Deshaies, W. Jacobsen, A. Singla, F. Li and R. Gorji
American Journal of Neuroradiology August 2012, 33 (7) 1411-1415; DOI: https://doi.org/10.3174/ajnr.A2971
E.M. Deshaies
aFrom the Departments of Neurosurgery (E.M.D., W.J., A.S.)
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W. Jacobsen
aFrom the Departments of Neurosurgery (E.M.D., W.J., A.S.)
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A. Singla
aFrom the Departments of Neurosurgery (E.M.D., W.J., A.S.)
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F. Li
bAnesthesiology (F.L., R.G.), SUNY Upstate Medical University, Syracuse, New York.
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R. Gorji
bAnesthesiology (F.L., R.G.), SUNY Upstate Medical University, Syracuse, New York.
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    Fig 1.

    A, Digital subtraction angiography demonstrating the tip of the Licox monitor in the ACA-MCA watershed territory. B, Reconstructed sagittal CT angiogram demonstrates the intraparenchymal location and depth of the fiberoptic Licox cable tip.

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    Fig 2.

    Prespasmolytic (A) and postspasmolytic (B) cerebral angiograms demonstrating improvement in cerebral vasospasm in ICA, ACA, and MCA vessels after intra-arterial verapamil infusion.

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    Fig 3.

    Point plot and column means graph displaying the PbO2 before and after spasmolysis in the mild-to-moderate vasospasm group (A) and moderate-to-severe vasospasm group (B). PbO2 values during the different cerebral angiographies are plotted as points along the y-axis with the mean and SD next to the point plot for both groups. Statistical significance (P < .05) was attained between pre- and posttreatment in both groups.

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  • Mild-to-moderate and moderate-to-severe group physiologic parameters before and after spasmolytic therapy along with percentage improvement in PbO2 after spasmolytic therapy

    Vasospasm SeverityTimingPbO2a (mm Hg ± SE)CPPb (mm Hg ± SE)ICPb (mm Hg ± SE)SaO2b (mm Hg ± SE)Fio2b (mm Hg ± SE)% PbO2 Improvement
    Mild-modPrespasmolysis35.2 ± 3.1110.9 ± 3.55.4 ± 2.299.6 ± 0.355.7 ± 3.514
    Postspasmolysis40.3 ± 3.1107.9 ± 4.04.6 ± 1.099.5 ± 0.355.5 ± 4.1
    Mod-sevPrespasmolysis27.3 ± 3.1116.7 ± 3.85.8 ± 1.399.8 ± 0.257.5 ± 6.140
    Postspasmolysis38.4 ± 3.2113.9 ± 4.47.8 ± 1.999.2 ± 0.557.0 ± 6.1
    • Note:—Mild-mod indicates mild-moderate; Mod-sev, moderate-severe.

    • ↵a Statistical significance (P ≤ .05).

    • ↵b No statistical significance (P > .05).

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American Journal of Neuroradiology: 33 (7)
American Journal of Neuroradiology
Vol. 33, Issue 7
1 Aug 2012
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Cite this article
E.M. Deshaies, W. Jacobsen, A. Singla, F. Li, R. Gorji
Brain Tissue Oxygen Monitoring to Assess Reperfusion after Intra-Arterial Treatment of Aneurysmal Subarachnoid Hemorrhage−Induced Cerebral Vasospasm: A Retrospective Study
American Journal of Neuroradiology Aug 2012, 33 (7) 1411-1415; DOI: 10.3174/ajnr.A2971

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Brain Tissue Oxygen Monitoring to Assess Reperfusion after Intra-Arterial Treatment of Aneurysmal Subarachnoid Hemorrhage−Induced Cerebral Vasospasm: A Retrospective Study
E.M. Deshaies, W. Jacobsen, A. Singla, F. Li, R. Gorji
American Journal of Neuroradiology Aug 2012, 33 (7) 1411-1415; DOI: 10.3174/ajnr.A2971
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