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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleBrain
Open Access

A Sparse Intraoperative Data-Driven Biomechanical Model to Compensate for Brain Shift during Neuronavigation

D.-X Zhuang, Y.-X Liu, J.-S Wu, C.-J Yao, Y Mao, C.-X Zhang, M.-N Wang, W Wang and L.-F Zhou
American Journal of Neuroradiology February 2011, 32 (2) 395-402; DOI: https://doi.org/10.3174/ajnr.A2288
D.-X Zhuang
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Y.-X Liu
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J.-S Wu
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C.-J Yao
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Y Mao
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C.-X Zhang
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M.-N Wang
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W Wang
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L.-F Zhou
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    Fig 1.

    A and B, Model-guided segmentation. The model (green) is aligned with the preoperative MR imaging to get a primitive result with a contour (bright gray) very close to the real contour (dark gray). C, Coarse mesh. D, Multiresolution mesh.

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    Fig 2.

    A, Surface scanning by LRS (left) after registration with the Excelim-04 system (middle) and PoleStar N20 iMRI system (right). B, The deformed surface (right side) acquired by LRS scanning. C, Transformation from the LRS space to the image space. D, Registration of the initial surface with the deforming surface.

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    Fig 3.

    A, The predictive deformation of mesh. The red mesh represents the preoperative surface, the blue mesh represents the deformed surface, and the yellow arrow indicates the direction of gravity. B, 3D visualization of the deformation field by the ray casting method (above) and the final warped MR images (below). The magnitude of the deformation increases as the color changes from dark red to bright red; the blue arrows near the frontal lobe indicate the direction of the deformation.

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    Table 1:

    Result of model validationa

    Patient No.Prediction Error (mm)Real Displacement (mm)Compensation Accuracy (%)
    11.785.2766.0
    21.494.5466.9
    31.916.2268.1
    41.294.3970.0
    51.605.2266.6
    61.734.3962.8
    71.314.7972.1
    81.654.5163.3
    91.735.9069.6
    101.907.6174.0
    111.397.2981.4
    • a All the values are mean values of the 4 markers of each patient.

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    Table 2:

    Comparison between subcortical and deep markers (paired t test)

    Mean ± SubcorticalMean ± DeepNo.TdfP Value
    Prediction error (mm)1.78 ± 0.331.46 ± 0.24112.93010.015
    Real displacement (mm)6.56 ± 1.934.37 ± 0.77113.99410.003
    Compensation accuracy (%)71.3 ± 6.166.8 ± 5.0113.22010.009
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    Table 3:

    Comparison of compensation accuracy between the horizontal and nonhorizontal bone window group

    Mean (%)SD (%)No.TdfPValue
    Horizontal72.05.362.3659.042
    Nonhorizontal65.72.95
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American Journal of Neuroradiology: 32 (2)
American Journal of Neuroradiology
Vol. 32, Issue 2
1 Feb 2011
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Cite this article
D.-X Zhuang, Y.-X Liu, J.-S Wu, C.-J Yao, Y Mao, C.-X Zhang, M.-N Wang, W Wang, L.-F Zhou
A Sparse Intraoperative Data-Driven Biomechanical Model to Compensate for Brain Shift during Neuronavigation
American Journal of Neuroradiology Feb 2011, 32 (2) 395-402; DOI: 10.3174/ajnr.A2288

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A Sparse Intraoperative Data-Driven Biomechanical Model to Compensate for Brain Shift during Neuronavigation
D.-X Zhuang, Y.-X Liu, J.-S Wu, C.-J Yao, Y Mao, C.-X Zhang, M.-N Wang, W Wang, L.-F Zhou
American Journal of Neuroradiology Feb 2011, 32 (2) 395-402; DOI: 10.3174/ajnr.A2288
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