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Research ArticleSpine Imaging and Spine Image-Guided Interventions

Diffusion Tensor MR Imaging of the Neurologically Intact Human Spinal Cord

B.M. Ellingson, J.L. Ulmer, S.N. Kurpad and B.D. Schmit
American Journal of Neuroradiology August 2008, 29 (7) 1279-1284; DOI: https://doi.org/10.3174/ajnr.A1064
B.M. Ellingson
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J.L. Ulmer
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S.N. Kurpad
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B.D. Schmit
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  • Fig 1.
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    Fig 1.

    FA images across the spinal cord for a representative subject.

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    Fig 2.

    Eigenvalue and anisotropy distributions for the entire spinal cord. A, Primary eigenvalue (λ1) histogram for control group. Bin frequency is shown as gray-scale level across the entire spinal cord (bin size = 1 × 10−5 mm2/s). Superimposed on the gray-scale histogram is the group mean and SD (solid black line and error bars). B, Secondary eigenvalue (λ2) histogram for control group. Bin frequency is shown as a gray-scale level across the entire spinal cord (bin size = 1 × 10−5 mm2/s). Superimposed on the gray-scale histogram is the group mean and SD (solid black line and error bars). C, Tertiary eigenvalue (λ3) histogram for the control group. Bin frequency is shown as a gray-scale level across the spinal cord (bin size = 1 × 10−5 mm2/s). Superimposed on the gray-scale histogram is the group mean and SD (solid black line and error bars). D, Fractional anisotropy histogram for control group. Bin frequency is shown as a gray-scale level across the spinal cord (bin size = 0.01). Superimposed on the gray-scale histogram is the group mean and SD (solid black line and error bars).

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    Fig 3.

    Primary eigenvalue, λ1; secondary eigenvalue, λ2; and tertiary eigenvalue, λ3, across the spinal cord for WM regions (A), ventral GM (B), and CSF (C). FA across the spinal cord (D) for individual WM regions, ventral GM, and CSF. Mean values are shown as solid black lines. Error bars indicate SD across subjects.

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    Fig 4.

    Regression analysis of mean apparent diffusion coefficients from DTI studies of the human spinal cord with use of a variety of pulse sequences. Numbers represent identification numbers and are located in the accompanying table. Results of logarithmic regression are also shown. Solid circle indicates average signal intensity attenuation for this study.

Tables

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  • Identification numbers (ID), study name/date, and pulse sequence used for studies included in regression analysis (Fig. 4)

    IDStudyPulse Sequence
    1Ellingson et al, 20067SS-EPI + Fuzzy logic
    2Robertson et al, 200026LSDI
    3Cercignani et al, 200314SENSE-EPI
    4Clark et al, 19999Nav. echo - SE
    5Murphy et al, 200127LSDI
    6Mamata et al, 20053LSDI
    7Holder et al, 200010Multishot SE-EPI
    8Bammer et al, 200012Phase nav., IEPI
    9Wheeler-Kingshott et al, 200223ZOOM-EPI
    10Maier and Mamata, 200528LSDI
    11Ries et al, 20008Multishot SE-EPI
    12Bammer et al, 200229FSE & IEPI
    13Clark et al, 20002Nav. echo - SE
    • Note:—SS-EPI indicates single-shot, echo-planar imaging; LSDI, line-scan diffusion imaging; IEPI, interleaved echo-planar imaging; SENSE, sensitivity encoding; SE, spin-echo; FSE, fast spin-echo; ZOOM-EPI, zonally magnified oblique multisection echo-planar imaging; nav., navigator.

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American Journal of Neuroradiology: 29 (7)
American Journal of Neuroradiology
Vol. 29, Issue 7
August 2008
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Cite this article
B.M. Ellingson, J.L. Ulmer, S.N. Kurpad, B.D. Schmit
Diffusion Tensor MR Imaging of the Neurologically Intact Human Spinal Cord
American Journal of Neuroradiology Aug 2008, 29 (7) 1279-1284; DOI: 10.3174/ajnr.A1064

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Diffusion Tensor MR Imaging of the Neurologically Intact Human Spinal Cord
B.M. Ellingson, J.L. Ulmer, S.N. Kurpad, B.D. Schmit
American Journal of Neuroradiology Aug 2008, 29 (7) 1279-1284; DOI: 10.3174/ajnr.A1064
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