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Research ArticleHEAD AND NECK

Contrast-Enhanced MR Angiography of the Carotid and Vertebrobasilar Circulations

Carina W. Yang, James C. Carr, Stephen F. Futterer, Mark D. Morasch, Benson P. Yang, Stephanie M. Shors and J. Paul Finn
American Journal of Neuroradiology September 2005, 26 (8) 2095-2101;
Carina W. Yang
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James C. Carr
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Stephen F. Futterer
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Mark D. Morasch
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Benson P. Yang
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Stephanie M. Shors
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J. Paul Finn
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    Fig 1.

    A 72-year-old man with suspected carotid artery disease.

    A, CE MRA of the carotid and vertebrobasilar circulations (3D FLASH, TR/TE, 4.36/1.64; flip angle 25°; bandwith, 432 Hz; matrix 136 × 512; field of view, 165 × 330 mm; slab thickness, 70 mm; partitions, 80; and voxel size, 1.33 × 0.64 × 1.15 mm3) shows stenoses in proximal left internal carotid artery (large arrow) and distal left vertebral artery (small arrow).

    B, CE MRA MIP image, with carotid vessels edited out, more clearly shows the left vertebral artery stenosis (arrow).

  • Fig 2.
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    Fig 2.

    A 65-year-old woman with headache, blurry vision, and arm weakness.

    A, CE MRA MIP image (3D FLASH, TR/TE, 4.36/1.64; flip angle 25°; bandwith, 432 Hz; matrix 136 × 512; field of view, 165 × 330 mm; slab thickness, 70 mm; partitions, 80; and voxel size, 1.33 × 0.64 × 1.15 mm3) of the vertebrobasilar system demonstrates severe stenosis at the origin of right vertebral artery (large arrow). There is a short segmental occlusion of the distal left vertebral artery (small arrow).

    B, Selective DSA of right subclavian confirms severe stenosis at the right vertebral origin (arrow).

    C, Selective DSA of left vertebral artery confirms the distal occlusion (arrow).

  • Fig 3.
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    Fig 3.

    A 46-year-old man with presyncope and right upper extremity weakness.

    A, CE MRA MIP image (3D FLASH, TR/TE, 4.36/1.64; flip angle 25°; bandwith, 432 Hz; matrix 136 × 512; field of view, 165 × 330 mm; slab thickness, 70 mm; partitions, 80; and voxel size, 1.33 × 0.64 × 1.15 mm3) of the vertebrobasilar system shows segmental occlusion of the proximal right vertebral artery (open arrow), as well as diffuse narrowing superior to the occluded segment (small arrows).

    B, Selective DSA of the right subclavian confirms occlusion (open arrow) and stenosis (closed arrows) in proximal right vertebral artery.

  • Fig 4.
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    Fig 4.

    A 59-year-old man with carotid and vertebrobasilar disease.

    A, CE MRA coronal MIP (3D FLASH, TR/TE, 4.36/1.64; flip angle 25°; bandwith, 432 Hz; matrix 136 × 512; field of view, 165 × 330 mm; slab thickness, 70 mm; partitions, 80; and voxel size of 1.33 × 0.64 × 1.15 mm3) of the carotid system showing high grade stenosis of the proximal left internal carotid artery (large arrow), with moderate stenosis involving the proximal right internal carotid artery (small arrow).

    B, CE MRA coronal MIP of the vertebrobasilar system with carotid vessels edited away demonstrates segmental occlusion of the right V1 segment (large arrow) with reconstitution distally and mulitfocal stenoses in V3 and V4 segments (small arrows). There is also a proximal left subclavian stenosis (open arrow).

    C, Selective DSA of the right carotid artery confirms stenosis in the proximal right internal carotid (arrow).

    D, Aortic arch angiography demonstrates focal stenosis of proximal left subclavian artery (arrow).

    E, Delayed image of DSA run confirms multifocal stenotic disease in the right V3 and V4 segments (small arrows), as well as segmental occlusion in the right V1 segment (large arrow).

Tables

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    TABLE 1:

    Sensitivity and specificity of contrast-enhanced MR angiography for the evaluation of disease in the carotid and vertebrobasilar circulations

    Observer 1Observer 2
    Sensitivity (%)Specificity (%)Sensitivity (%)Specificity (%)
    Stenosis only
        ICA889710099
        VB8699100100
        ICA + VB8799100100
    Occlusion only
        ICA100100100100
        VB83997999
        ICA + VB86998299
    Stenosis and occlusion
        ICA929710099
        VB86988799
        ICA + VB88989199
    All disease
        ICA949710097
        VB88988899
        ICA + VB90979298
    • Note.—ICA indicates internal carotid artery; VB, vertebrobasilar circulation.

    • View popup
    TABLE 2:

    Interobserver variability of contrast-enhanced MR angiography for the evaluation of stenosis and occlusion in the carotid and vertebrobasilar circulations

    Interobserver Variability (%)κ
    ICA990.91
    VB980.86
    ICA + VB980.92
    • Note.—ICA indicates internal carotid artery; VB, vertebrobasilar circulation.

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American Journal of Neuroradiology: 26 (8)
American Journal of Neuroradiology
Vol. 26, Issue 8
1 Sep 2005
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Cite this article
Carina W. Yang, James C. Carr, Stephen F. Futterer, Mark D. Morasch, Benson P. Yang, Stephanie M. Shors, J. Paul Finn
Contrast-Enhanced MR Angiography of the Carotid and Vertebrobasilar Circulations
American Journal of Neuroradiology Sep 2005, 26 (8) 2095-2101;

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Contrast-Enhanced MR Angiography of the Carotid and Vertebrobasilar Circulations
Carina W. Yang, James C. Carr, Stephen F. Futterer, Mark D. Morasch, Benson P. Yang, Stephanie M. Shors, J. Paul Finn
American Journal of Neuroradiology Sep 2005, 26 (8) 2095-2101;
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  • Contrast-Enhanced MR Angiography Is Not More Accurate Than Unenhanced 2D Time-of-Flight MR Angiography for Determining >=70% Internal Carotid Artery Stenosis
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