Advertisement

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleBRAIN

Tissue at Risk Is Overestimated in Perfusion-Weighted Imaging: MR Imaging in Acute Stroke Patients without Vessel Recanalization

Thomas Kucinski, Dirk Naumann, René Knab, Volker Schoder, Susanne Wegener, Jens Fiehler, Amitava Majumder, Joachim Röther and Hermann Zeumer
American Journal of Neuroradiology April 2005, 26 (4) 815-819;

References

  1. ↵
    Moseley ME, Cohen Y, Mintorovitch J, et al. Early detection of regional cerebral ischemia in cats: comparison of diffusion- and T2-weighted MRI and spectroscopy. Magn Reson Med 1990;14:330–346
    CrossRefPubMedWeb of Science
  2. Fisher M, Prichard JW, Warach S. New magnetic resonance techniques for acute ischemic stroke. JAMA 1995;274:908–911
    CrossRefPubMedWeb of Science
  3. ↵
    Schellinger PD, Jansen O, Fiebach JB, et al. Feasibility and practicality of MR imaging of stroke in the management of hyperacute cerebral ischemia. AJNR Am J Neuroradiol 2000;21:1184–1189
    Abstract/FREE Full Text
  4. ↵
    Schlaug G, Benfield A, Baird AE, et al. The ischemic penumbra: operationally defined by diffusion and perfusion MRI. Neurology 1999;53:1528–1537
    Abstract/FREE Full Text
  5. ↵
    Neumann Haefelin T, Wittsack HJ, Wenserski F, et al. Diffusion- and perfusion-weighted MRI: the DWI/PWI mismatch region in acute stroke. Stroke 1999;30:1591–1597
    Abstract/FREE Full Text
  6. ↵
    Sorensen AG, Copen WA, Ostergaard L, et al. Hyperacute stroke: simultaneous measurement of relative cerebral blood volume, relative cerebral blood flow, and mean tissue transit time. Radiology 1999;210:519–527
    PubMedWeb of Science
  7. ↵
    Albers GW. Expanding the window for thrombolytic therapy in acute stroke: the potential role of acute MRI for patient selection. Stroke 1999;30:2230–2237
    Abstract/FREE Full Text
  8. ↵
    Rother J, Schellinger PD, Gass A, et al. Effect of intravenous thrombolysis on MRI parameters and functional outcome in acute stroke <6 hours. Stroke 2002;33:2438–2445
    Abstract/FREE Full Text
  9. ↵
    Donnan GA, Davis SM. Neuroimaging, the ischaemic penumbra, and selection of patients for acute stroke therapy. Lancet Neurol 2002;1:417–425
    CrossRefPubMedWeb of Science
  10. ↵
    Grandin CB. Assessment of brain perfusion with MRI: methodology and application to acute stroke. Neuroradiology 2003;45:755–766
    CrossRefPubMed
  11. ↵
    Ostergaard L, Sorensen AG, Kwong KK, et al. High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part II. Experimental comparison and preliminary results. Magn Reson Med 1996;36:726–736
    CrossRefPubMedWeb of Science
  12. ↵
    Schellinger PD, Fiebach JB, Hacke W. Imaging-based decision making in thrombolytic therapy for ischemic stroke: present status. Stroke 2003;34:575–583
    Abstract/FREE Full Text
  13. ↵
    Fiehler J, Foth M, Kucinski T, et al. Severe ADC decreases do not predict irreversible tissue damage in humans. Stroke 2002;33:79–86
    Abstract/FREE Full Text
  14. ↵
    Kucinski T, Vaterlein O, Glauche V, et al. Correlation of apparent diffusion coefficient and computed tomography density in acute ischemic stroke. Stroke 2002;33:1786–1791
    Abstract/FREE Full Text
  15. ↵
    Astrup J, Siesjo BK, Symon L. Thresholds in cerebral ischemia: the ischemic penumbra. Stroke 1981;12:723–725
    FREE Full Text
  16. ↵
    Kucinski T, Koch C, Eckert B, et al. Collateral circulation is an independent radiological predictor of outcome after thrombolysis in acute ischaemic stroke. Neuroradiology 2003;45:11–18
    PubMedWeb of Science
  17. ↵
    Caramia F, Huang Z, Hamberg LM, et al. Mismatch between cerebral blood volume and flow index during transient focal ischemia studied with MRI and GD-BOPTA. Magn Reson Imaging 1998;16:97–103
    CrossRefPubMed
  18. ↵
    Singer OC, De Rochemont Rdu M, Foerch C, et al. Relation between relative cerebral blood flow, relative cerebral blood volume, and mean transit time in patients with acute ischemic stroke determined by perfusion-weighted MRI. J Cereb Blood Flow Metab 2003;23:605–611
    CrossRefPubMedWeb of Science
  19. ↵
    Lin W, Lee JM, Lee YZ, et al. Temporal relationship between apparent diffusion coefficient and absolute measurements of cerebral blood flow in acute stroke patients. Stroke 2003;34:64–70
    Abstract/FREE Full Text
  20. ↵
    Schaefer PW, Ozsunar Y, He J, et al. Assessing tissue viability with MR diffusion and perfusion imaging. AJNR Am J Neuroradiol 2003;24:436–443
    Abstract/FREE Full Text
  21. ↵
    Butcher K, Parsons M, Baird T, et al. Perfusion thresholds in acute stroke thrombolysis. Stroke 2003;34:2159–2164
    Abstract/FREE Full Text
  22. Liu Y, Karonen JO, Vanninen RL, et al. Cerebral hemodynamics in human acute ischemic stroke: a study with diffusion- and perfusion-weighted magnetic resonance imaging and SPECT. J Cereb Blood Flow Metab 2000;20:910–920
    PubMedWeb of Science
  23. Shih LC, Saver JL, Alger JR, et al. Perfusion-weighted magnetic resonance imaging thresholds identifying core, irreversibly infarcted tissue. Stroke 2003;34:1425–1430
    Abstract/FREE Full Text
  24. ↵
    Rohl L, Ostergaard L, Simonsen CZ, et al. Viability thresholds of ischemic penumbra of hyperacute stroke defined by perfusion-weighted MRI and apparent diffusion coefficient. Stroke 2001;32:1140–1146
    Abstract/FREE Full Text
  25. ↵
    Wu O, Ostergaard L, Koroshetz WJ, et al. Effects of tracer arrival time on flow estimates in MR perfusion-weighted imaging. Magn Reson Med 2003;50:856–864
    CrossRefPubMed
  26. ↵
    Calamante F, Gadian DG, Connelly A. Delay and dispersion effects in dynamic susceptibility contrast MRI: simulations using singular value decomposition. Magn Reson Med 2000;44:466–473
    CrossRefPubMed
  27. ↵
    Schellinger PD, Fiebach JB, Jansen O, et al. Stroke magnetic resonance imaging within 6 hours after onset of hyperacute cerebral ischemia. Ann Neurol 2001;49:460–469
    CrossRefPubMedWeb of Science
  28. ↵
    Rordorf G, Koroshetz WJ, Copen WA, et al. Regional ischemia and ischemic injury in patients with acute middle cerebral artery stroke as defined by early diffusion-weighted and perfusion-weighted MRI. Stroke 1998;29:939–943
    Abstract/FREE Full Text
  29. ↵
    Fiehler J, Knudsen K, Kucinski T, et al. Predictors of apparent diffusion coefficient normalization in stroke patients. Stroke 2004;35:514–519
    Abstract/FREE Full Text
  30. ↵
    Arnold M, Nedeltchev K, Mattle HP, et al. Intra-arterial thrombolysis in 24 consecutive patients with internal carotid artery T occlusions. J Neurol Neurosurg Psychiatry 2003;74:739–742
    Abstract/FREE Full Text
  31. ↵
    Kucinski T, Koch C, Grzyska U, et al. The predictive value of early CT and angiography for fatal hemispheric swelling in acute stroke. AJNR Am J Neuroradiol 1998;19:839–846
    Abstract
Back to top

In this issue

Advertisement
Print
Download PDF
Email Article
Cite this article
0 Responses
Respond to this article
Bookmark this article
Tissue at Risk Is Overestimated in Perfusion-Weighted Imaging: MR Imaging in Acute Stroke Patients without Vessel Recanalization
Thomas Kucinski, Dirk Naumann, René Knab, Volker Schoder, Susanne Wegener, Jens Fiehler, Amitava Majumder, Joachim Röther, Hermann Zeumer
American Journal of Neuroradiology Apr 2005, 26 (4) 815-819;
del.icio.us logo Twitter logo Facebook logo Mendeley logo

Jump to section

Advertisement