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Research ArticleBRAIN

PC VIPR: A High-Speed 3D Phase-Contrast Method for Flow Quantification and High-Resolution Angiography

Tianliang Gu, Frank R. Korosec, Walter F. Block, Sean B. Fain, Quill Turk, Darren Lum, Yong Zhou, Thomas M. Grist, Victor Haughton and Charles A. Mistretta
American Journal of Neuroradiology April 2005, 26 (4) 743-749;
Tianliang Gu
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Frank R. Korosec
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Walter F. Block
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Sean B. Fain
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Quill Turk
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Darren Lum
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Yong Zhou
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Thomas M. Grist
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Victor Haughton
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Charles A. Mistretta
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    Fig 1.

    Comparison of 3DPC (A, B) with a PCVIPR (C, D) acquisition having an acceleration factor of 17. In this case, comparable imaging times were used and the acceleration is due to a factor of 2.5 in volume coverage and a factor of 7 reduction in voxel volume. No pulsatile artifact appears on the PCVIPR image (C) as it does on the 3DPC image (A, arrows).

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    Fig 2.

    Comparison of 3DPC (A, B) with a PCVIPR (C, D) acquisition having an acceleration factor of 30. In this case residual contrast was present and the acceleration is due to a factor of 4.5 in volume coverage and a factor of 7 reduction in voxel volume.

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    Fig 3.

    Comparison of 3DPC (A, B) with a PCVIPR (C, D) acquisition having an acceleration factor of 61. The acceleration is due to a factor of 4.5 in volume coverage, a factor of 7 reduction in voxel volume, and a factor of 2 reduction in imaging time. Visualization of some small vessels is decreased in the PCVIPR examination, which indicates insufficient SNR to support this acceleration factor.

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    Fig 4.

    Basic PCVIPR in vitro average flow measurement validation on a pulsatile flow on the flow phantom. Ten flow rates were measured. The PCVIPR results are plotted against the computer-set flow rates. One standard deviation is plotted as the error bar on each data point. A linear relationship was reached, with a linear fit slope of 0.94 and an R2 = 0.99.

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    Fig 5.

    In vivo flow measurement validation by using 2D cine PC MR on the right ICA and the basilar artery of six volunteers. One standard deviation is used to plot the error bar on each data point. The correlation of the two methods is shown here with R2 = 0.97.

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    Fig 6.

    When no posterior communicating arteries exist in the volunteer, the basilar artery is the only blood supplier to the two PCAs (B). The flow rates from the two PCAs were measured as shown in C, whereas the flow rate of the basilar artery was measured at the location as shown in B. As shown in A, the sum of the two PCA flow rates were very close to that of the basilar artery, where 1 SD was used as the error bar.

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American Journal of Neuroradiology: 26 (4)
American Journal of Neuroradiology
Vol. 26, Issue 4
1 Apr 2005
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Cite this article
Tianliang Gu, Frank R. Korosec, Walter F. Block, Sean B. Fain, Quill Turk, Darren Lum, Yong Zhou, Thomas M. Grist, Victor Haughton, Charles A. Mistretta
PC VIPR: A High-Speed 3D Phase-Contrast Method for Flow Quantification and High-Resolution Angiography
American Journal of Neuroradiology Apr 2005, 26 (4) 743-749;

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PC VIPR: A High-Speed 3D Phase-Contrast Method for Flow Quantification and High-Resolution Angiography
Tianliang Gu, Frank R. Korosec, Walter F. Block, Sean B. Fain, Quill Turk, Darren Lum, Yong Zhou, Thomas M. Grist, Victor Haughton, Charles A. Mistretta
American Journal of Neuroradiology Apr 2005, 26 (4) 743-749;
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