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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleNeurointervention

North American Clinical Experience with the EKOS MicroLysUS Infusion Catheter for the Treatment of Embolic Stroke

Brian R. Mahon, Gary M. Nesbit, Stanley L. Barnwell, Wayne Clark, Thomas R. Marotta, Alain Weill, Phillip A. Teal and Adnan I. Qureshi
American Journal of Neuroradiology March 2003, 24 (3) 534-538;
Brian R. Mahon
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Gary M. Nesbit
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Stanley L. Barnwell
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Wayne Clark
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Thomas R. Marotta
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Alain Weill
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Phillip A. Teal
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Adnan I. Qureshi
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    Fig 1.

    Recanalization rates in the EKOS study (all patients) versus the PROACT II study.

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    TABLE 1:

    Demographics of the treated population

    Patient/Age, y/SexInitial NIHSS ScoreTime to TreatmentTime to RecanalizationFinal TIMISymptomatic ICH90-Day NIHSS Score90-Day Change in ΔNIHSS Score90-Day mRS Score90-Day BI
    MCA occlusion
     1/66/F235.83NA0No4−19218
     2/64/F214.38603No3−18317
     3/70/M223.5152NoNANANANA
     4/77/M214.75452NoDDDD
     5/72/F123.75NA2No3−9117
    Carotid T occlusion
     6/71/F184.0603No12−64 3
     7/66/M174.5553YesDDDD
     8/64/M95.75302, 3ACANo3−6218
     9/64/M224.25450, 3ACANo2−20120
     10/65/M174.25302, 0ACANoDDDD
    Posterior circulation occlusion
     11/44/F134.8NA0NoDDDD
     12/40/F119.75NA2No1−10220
     13/68/M244.75713No5−19318
     14/58/F2713603YesDDDD
    • Note.—ACA indicates anterior cerebral artery; D, died; ICH, intracranial hemorrhage; and NA, not available.

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    TABLE 2:

    Comparison of secondary clinical outcomes in the EKOS study (all patients) versus the PROACT II study

    Secondary 90-Day OutcomeEKOS StudyPROACT II Study
    mRS score ≤ 1, %1426
    mRS score ≤ 2, %4340
    mRS score ≤ 3, %57
    BI ≥ 90, %3641
    BI ≥ 60, %5054
    NIHSS score ≤ 1, %1418
    NIHSS score ≤ 4, %50
    Decrease in NIHSS score ≥ 50%, %5750
    Symptomatic intracranial hemorrhage, %1410
    Mortality rate, %3625
    Total no. of patients14104
    Average time to treatment, h5.524.70
    Average time to lysis, min40NA
    • Note.—NA indicates not applicable.

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American Journal of Neuroradiology: 24 (3)
American Journal of Neuroradiology
Vol. 24, Issue 3
1 Mar 2003
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Brian R. Mahon, Gary M. Nesbit, Stanley L. Barnwell, Wayne Clark, Thomas R. Marotta, Alain Weill, Phillip A. Teal, Adnan I. Qureshi
North American Clinical Experience with the EKOS MicroLysUS Infusion Catheter for the Treatment of Embolic Stroke
American Journal of Neuroradiology Mar 2003, 24 (3) 534-538;

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North American Clinical Experience with the EKOS MicroLysUS Infusion Catheter for the Treatment of Embolic Stroke
Brian R. Mahon, Gary M. Nesbit, Stanley L. Barnwell, Wayne Clark, Thomas R. Marotta, Alain Weill, Phillip A. Teal, Adnan I. Qureshi
American Journal of Neuroradiology Mar 2003, 24 (3) 534-538;
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