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540 Transcriptionally defined immune landscape in human gliomas
Pravesh Gupta, Minghao Dang, Krishna Bojja, Huma Shehwana, Tuan Tran, Linghua Wang, Krishna Bhat

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A328-A329; DOI: 10.1136/jitc-2020-SITC2020.0540
542 Expansion of cytotoxic NK Cells from PBMCs using individualized cytokine combination
Andreia Maia, Joana Lerias, Markus Maeurer, Mireia Castillo-Martin

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A329-A330; DOI: 10.1136/jitc-2020-SITC2020.0542
53 Predictors of response to immune checkpoint inhibitor therapy in metastatic solid tumors: real world evidence
Aasems Jacob, Jianrong Wu, Jill Kolesar, Eric Durbin, Aju Mathew, Susanne Arnold, Aman Chauhan

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A33-A35; DOI: 10.1136/jitc-2020-SITC2020.0053
543 Natural killer cells restrict the growth of liver metastases in nude hosts
Alexandra Quackenbush, Pepper Schedin

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A330-A331; DOI: 10.1136/jitc-2020-SITC2020.0543
545 Tumor-specific cytolytic CD4 T cells mediate protective immunity against human cancer
Amélie Cachot, Mariia Bilous, Yen-Cheng Liu, Xiaokang Li, Alexander Rockinger, Margaux Saillard, Tania Wyss, Philippe Guillaume, Julien Schmidt, Raphael Genolet, Maria Pia Protti, Walter Reith, Laurence De Leval, Kalliopi Ioannidou, George Coukos, Alexandre Harari, Daniel Speiser, Alexander Mathis, David Gfeller, Hatice Altug, Pedro Romero, Camilla Jandus

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A331; DOI: 10.1136/jitc-2020-SITC2020.0545
547 Identification of the immune landscape in penile squamous cell carcinoma using multiplex immunofluorescence and spatial image analysis
Rossana Lazcano Segura, Santhoshi Krishnan, Morgan Oneka, Federico Netto, Xin Lu, Priya Rao, Renganayaki Pandurengan, Curtis Pickering, Curtis Pettaway, Jad Chahoud, Edwin Parra

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A332-A333; DOI: 10.1136/jitc-2020-SITC2020.0547
549 Characterizing double positive T cells in the tumor microenvironment: a tale of promiscuous cell fates
Sara Schad, Andrew Chow, Heng Pan, Levi Mangarin, Roberta Zappasodi, Mathieu Gigoux, David Redmond, Daniel Hirschhorn-Cymerman, Sadna Budhu, Hong Zhong, Xia Yang, Olivier Elemento, Jedd Wolchok, Taha Merghoub

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A333-A334; DOI: 10.1136/jitc-2020-SITC2020.0549
550 An Axl-targeting monoclonal antibody that inhibits Axl activity and potently stimulates the innate immune response
Diego Alvarado, Laura Vitale, Mike Murphy, Thomas O’Neill, Edward Natoli, Jay Lillquist, Linda Crew, Anna Wasiuk, Jeffrey Weidlick, Crystal Sisson, Jenifer Widger, Laura Mills-Chen, Andrea Crocker, Colleen Patterson, James Boyer, Eric Forsberg, April Baronas, Taylor Mathieu, Amelia Fields, Russell Hammond, Li-Zhen He, Joel Goldstein, Lawrence Thomas, Henry March, Tibor Keler

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A334; DOI: 10.1136/jitc-2020-SITC2020.0550
553 CUE-100 series Immuno-STATs from concept to the clinic: Leveraging protein engineering to stimulate and selectively deliver affinity-attenuated IL-2 to antigen-specific T cells
Alex Histed, Natasha Girgis, Miguel Moreta, Jonathan Soriano, BS Luke Witt, Zohra Merazga, Fulvio Diaz, Fan Zhao, Melissa Kemp, Paige Ruthardt, Dharma Thapa, Anish Suri, Ronald Seidel, Kenneth Pienta, Mary Simcox, Steven Quayle, John Ross, Saso Cemerski

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A335-A336; DOI: 10.1136/jitc-2020-SITC2020.0553
558 Programmed death (PD)-1 and PD-ligand-1 inhibitors in the treatment of non-small cell lung cancer: a systematic review of their efficacy and safety
Melissa Lingohr-Smith, Chelsea Deitelzweig, Grace Lin, Jay Lin

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A337; DOI: 10.1136/jitc-2020-SITC2020.0558

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