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55 Thousands of antigens are recognized in mice via endogenous antibodies after being cured of a B78 melanoma via immunotherapy
Anna Hoefges, Amy Erbe, Sean Mcilwain, Trang Le, Angie Xu, Nicholas Mathers, Eric Zhang, Andrew Melby, Claire Baniel, Alexander Rakhmilevich, Jacquelyn Hank, Richard Pinapati, Brad Garcia, Jigar Patel, Zachary Morris, Irene Ong, Paul Sondel

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A35; DOI: 10.1136/jitc-2020-SITC2020.0055
54 Patient stratification using clinical proteomics – validated multiplexed MRM assays to quantify HER2 and other biomarkers in clinical FFPE tissues
Maxim Isabelle, Michael Schirm, Gwenaël Pottiez, Rudolf Guilbaud, Lorella Di Donato

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A35; DOI: 10.1136/jitc-2020-SITC2020.0054
584 Therapeutic vascular normalization to promote tumor-associated tertiary lymphoid structures
Jessica Filderman, Manoj Chelvanambi, Walter Storkus

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A350; DOI: 10.1136/jitc-2020-SITC2020.0584
585 Intralesional injection of rose bengal improves the efficacy of gemcitabine chemotherapy against pancreatic cancer
Patrick Innamarato, Shari Pilon-Thomas, Jennifer Morse, Sarah Asby, Amy Mackay, Matthew Beatty, Jaime Blauvelt, Scott Kidd, John Mullinax

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A350; DOI: 10.1136/jitc-2020-SITC2020.0585
587 Tumor-activated Fc-engineered anti-CTLA-4 monoclonal antibody, XTX101, demonstrates tumor-selective PD and efficacy in preclinical models
Kurt Jenkins, Parker Johnson, Minjie Zhang, Wilson Guzman, Ugur Eskiocak, Megan McLaughlin, Caitlin O’Toole, Magali Pederzoli-Ribeil, Miso Park, John Williams, Margaret Karow, Jennifer O’Neil, Timothy Clackson, Ronan O’Hagan

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A351; DOI: 10.1136/jitc-2020-SITC2020.0587
586 Intratumoral DNA-based gene transfer as an efficient delivery approach to combine checkpoint-inhibiting antibodies with interleukin 12
Liesl Jacobs, Elien De Smidt, Nick Geukens, Kevin Hollevoet, Paul Declerck

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A351; DOI: 10.1136/jitc-2020-SITC2020.0586
588 Targeting GITR enhances human tumour-infiltrating T cell functionality in mismatch repair proficient primary colorectal carcinoma and liver metastases
Yannick Rakké, Lucia Campos Carrascosa, Adriaan van Beek, Valeska de Ruiter, Michael Doukas, Susan ter Borg, Pascal Doornebosch, Maarten Vermaas, Erwin van der Harst, Peter Paul Coene, Dirk Grünhagen, Cornelis Verhoef, Jan IJzermans, Dave Sprengers, Jaap Kwekkeboom

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A352; DOI: 10.1136/jitc-2020-SITC2020.0588
589 Efficacy of oncolytic vaccinia virus requires infection of suppressive immune cells in the tumor microenvironment leading to their reprogramming and deletion
Kristin DePeaux, Paolo Vignali, Saumendra Sarkar, Greg Delgoffe

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A352-A353; DOI: 10.1136/jitc-2020-SITC2020.0589
590 Pre-conditioning of the tumor microenvironment with oncolytic reovirus converts CD3-bispecific antibody treatment into effective immunotherapy
Christianne Groeneveldt, Priscilla Kinderman, Diana JM van den Wollenberg, Ruben L van den Oever, Jim Middelburg, Dana AM Mustafa, Rob Hoeben, Sjoerd van der Burg, Thorbald van Hall, Nadine Van Montfoort

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A353-A354; DOI: 10.1136/jitc-2020-SITC2020.0590
592 Enhancing the therapeutic potential of oncolytic adenoviruses with vSENS™ technology
Goo-Young Kim, Ji Yeon Son, So Jin Lee, Sang Woo Jo, Changhoon In, Sang Hoon Kim, Joon Young Park, So-Young Kim, Gyu-Young Moon, Ji-Hye Choi, Suk-Hwan Kim, Minhyuk Yun, Hye Yeong Nam, Helen Cho

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A354-A355; DOI: 10.1136/jitc-2020-SITC2020.0592

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