topic

753 The immune landscape of papillary thyroid cancer and its association with neoantigen landscape and DNA repair gene mutations
Myungwoo Nam, Woojung Yang, Ju Young Lee, Jaeyoun Choi, Hansol Choi, Eugene Kim, Emma Yu, Jin Young Hwang, William Bae, Chan Mi Jung, Victor Wang, Jeffrey Chuang, Young Kwang Chae

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A452; DOI: 10.1136/jitc-2020-SITC2020.0753
756 Assessment of the immune checkpoint landscape in head and neck squamous cell carcinoma by single-cell RNA sequencing and multispectral imaging
Lazar Vujanovic, Aditi Kulkarni, Cornelius Kürten, Anthony Cillo, Patricia Santos, Stephan Lang, Uma Duvvuri, Seungwon Kim, Heath Skinner, Tullia Bruno, Dario Vignali, Riyue Bao, Robert Ferris

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A453-A454; DOI: 10.1136/jitc-2020-SITC2020.0756
755 CXCR1 and CXCR2 chemokine receptor agonists produced by tumors induce neutrophil extracellular traps that interfere with immune cytotoxicity
Alvaro Teijeira, Saray Garasa, Itziar Migueliz, Assunta Cirella, Ignacio Melero

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A453; DOI: 10.1136/jitc-2020-SITC2020.0755
758 Identification of tumor antigen-specific T cells in the peripheral blood of colorectal cancer patients
Emilie Picard, Alexandrine Martel, Alain Simard, Hoang-Thanh Le, Chris Verschoor, Grace Ma, Graham Pawelec

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A454-A455; DOI: 10.1136/jitc-2020-SITC2020.0758
759 Development of an implantable artificial lymph node as a therapeutic cancer vaccine
Dixita Viswanath, Hsuan-Chen Liu, Corrine Ying Xuan Chua, Alessandro Grattoni

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A455; DOI: 10.1136/jitc-2020-SITC2020.0759
763 Expanded and activated TILs kill tumor cells enabling IO compound assays
Paula Comune Pennacchi, Paloma Navarro, Verónica García Navas, Arántzazu Barquín García, Elena Sevillano Fernández, Sergio Ruiz Llorente, Juan Francisco Rodriguez, Monica Yagüe, Joan Ballesteros, Daniel Primo, Jesus Garcia Donas Jimenez

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A457; DOI: 10.1136/jitc-2020-SITC2020.0763
765 Contextual secretion of nanoscale interleukin (IL)-12 by CAR T cells for the treatment of cancer
Zhifen Yang, Maggie Bobbins, Hana Choi, Ofir Stefanson, Jin Yang, Khristina Magallanes, Bing Wang, Lei Stanley Qi, Francesco Marincola

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A458; DOI: 10.1136/jitc-2020-SITC2020.0765
767 Interferon gamma reduces CAR-T exhaustion and toxicity without compromising therapeutic efficacy in hematologic malignancies
Stefanie Bailey, Sonika Vatsa, Amanda Bouffard, Rebecca Larson, Irene Scarfo, Michael Kann, Andrea Schmidts, Marcela Maus

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A459; DOI: 10.1136/jitc-2020-SITC2020.0767
771 Characterization of tumor infiltrating immune cells from adult soft tissue sarcomas
Jacky Chen, Jay Wunder, Nalan Gokgoz, Irene Andrulis

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A461-A463; DOI: 10.1136/jitc-2020-SITC2020.0771
770 Analysis of gut microbiome in patients receiving adoptive T-cell therapy (ACT) across different solid tumour types
Arantzazu Barquin Garcia, Sergio Ruiz, Paloma Navarro, Juan Francisco Rodriguez-Moreno, Elena Sevillano, Monica Yague, Sandra Amarilla, Jesus Garcia-Donas

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A461; DOI: 10.1136/jitc-2020-SITC2020.0770

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