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1309 Deep learning reveals predictive immune signature of response to checkpoint blockade in multiplexed spatial immunohistochemistry data
John-William Sidhom, Jonathan Anker, Guray Akturk, Sudeh Izadmehr, Justin David, Saurabh Gupta, Seunghee Kim-Schulze, Padmanee Sharma, Sacha Gnjatic, Matthew Galsky

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1454-A1456; DOI: 10.1136/jitc-2023-SITC2023.1309
1310 Supporting dose decisions for antibody drug conjugates (ADC) through combined efficacy and toxicity modeling
Khomveer Singh, Rahul Sing, Bhairav Paleja, Madhav Channavazzala

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1457-A1458; DOI: 10.1136/jitc-2023-SITC2023.1310
1311 H&E 2.0: deep learning-enabled identification of tumor-specific CD39+CD8+ T cells in marker-free images for predicting immunotherapy response
Felicia Wee, Willa Yim, Jia Meng, Jeffrey Lim, Craig Joseph, Xinru Lim, Kai Soon Ng, Jiang Feng Ye, Zhen Wei Neo, Li Yen Chong, Chan Way Ng, Kiat Hon Lim, Mai Chan Lau, Joe Yeong

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1459-A1460; DOI: 10.1136/jitc-2023-SITC2023.1311
1312 Identification and validation of immunogenic clonal neoantigens for personalized therapies
Gareth Wilson, Fong Chan, Elizabeth Larose Cadieux, Max Salm, Hugh O’Brien, Karen Matthews, Theres Oakes, Katy Newton, Karl Peggs, Martin Forster, Samra Turajlic, Andrew Craig, Sergio A Quezada

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1461; DOI: 10.1136/jitc-2023-SITC2023.1312
1313 UltiStacker™: easy to use multimodal image co-registration with sub-cellular accuracy
Douglas Wood, Gourab Chatterjee, Angela Vasaturo

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1462; DOI: 10.1136/jitc-2023-SITC2023.1313
1314 Polarity measurements from multiplex imaging suggest immune cell activation
Eric Wu, Aaron Mayer, Alexandro E Trevino, James Zou

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1463-A1464; DOI: 10.1136/jitc-2023-SITC2023.1314
1315 Identification and generalization of tissue structures with spatial cellular graph partitioning (SCGP)
Zhenqin Wu, James Zou, Aaron Mayer, Alexandro E Trevino

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1465; DOI: 10.1136/jitc-2023-SITC2023.1315
1042 Modulation of immune landscape in glioblastoma by CXCL12 inhibition
Chen Cam-El Makranz, Meili Zhang, Dionne Davis, Hua Song, Nicole Briceno, Wei Zhang, Mark Gilbert, Masashi Watanabe

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1149; DOI: 10.1136/jitc-2023-SITC2023.1042
1043 Intratumoral mRNA IL-12 can induce a dose dependent immunostimulatory effect within tumor microenvironment in patients with advanced solid tumors
Michael Abadier, Jacky Chow, Linh Van, Vasudha Sehgal, Igor Feldman, Khanh Do, Praveen Aanur, Nicholas Durham, Xiaoru Chen, Yuling Wu, Paula G Fraenkel, Analia Azaro, Eduardo Castanon Alvarez, Dmitriy Zamarin, Benedito Carneiro, Thomas Marron, Sandip P Patel, Vivek Subbiah, Inderjit Mehmi, Arjun Oberoi, Anthony El-Khoueiry, Omid Hamid

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1150; DOI: 10.1136/jitc-2023-SITC2023.1043
1044 High dose of rhIL-10 enhances CD8 T cell and NK cell mediated tumor cell killing in vitro
Elli Narvi, Anna Brunell, Anu Autio, Anil Thotakura

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1151; DOI: 10.1136/jitc-2023-SITC2023.1044

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