Basic Tumor Immunology

Vaccine efficacy against primary and metastatic cancer with in vitro-generated CD103⁺ conventional dendritic cells
Yifan Zhou, Natalie Slone, Taylor T Chrisikos, Oleksandr Kyrysyuk, Rachel L Babcock, Yusra B Medik, Haiyan S Li, Eugenie S Kleinerman, Stephanie S Watowich

Journal for ImmunoTherapy of Cancer Apr 2020, 8 (1) e000474; DOI: 10.1136/jitc-2019-000474
TFEB is a master regulator of tumor-associated macrophages in breast cancer
Yong Li, Johnie Hodge, Qing Liu, Junfeng Wang, Yuzhen Wang, Trent D Evans, Diego Altomare, Yongzhong Yao, E Angela Murphy, Babak Razani, Daping Fan

Journal for ImmunoTherapy of Cancer Jun 2020, 8 (1) e000543; DOI: 10.1136/jitc-2020-000543
Bivalent therapeutic vaccine against HPV16/18 genotypes consisting of a fusion protein between the extra domain A from human fibronectin and HPV16/18 E7 viral antigens
Laura Arribillaga, Iciar Echeverria, Viriginia Belsue, Timothy Gomez, Teresa Lozano, Noelia Casares, Lorea Villanueva, Sonia Domingos-Pereira, Pedro J Romero, Denise Nardelli-Haefliger, Sandra Hervás-Stubbs, Pablo Sarobe, María Josefa Rodriguez, José L Carrascosa, Thomas Zürcher, Juan José Lasarte

Journal for ImmunoTherapy of Cancer Jun 2020, 8 (1) e000704; DOI: 10.1136/jitc-2020-000704
Targeting ANXA1 abrogates Treg-mediated immune suppression in triple-negative breast cancer
Fang Bai, Peng Zhang, Yipeng Fu, Hongliang Chen, Mingdi Zhang, Qianru Huang, Dan Li, Bin Li, Kejin Wu

Journal for ImmunoTherapy of Cancer Apr 2020, 8 (1) e000169; DOI: 10.1136/jitc-2019-000169
High dose-rate brachytherapy of localized prostate cancer converts tumors from cold to hot
Simon P Keam, Heloise Halse, Thu Nguyen, Minyu Wang, Nicolas Van Kooten Losio, Catherine Mitchell, Franco Caramia, David J Byrne, Sue Haupt, Georgina Ryland, Phillip K Darcy, Shahneen Sandhu, Piers Blombery, Ygal Haupt, Scott G Williams, Paul J Neeson

Journal for ImmunoTherapy of Cancer Jun 2020, 8 (1) e000792; DOI: 10.1136/jitc-2020-000792
Immune involvement of the contralateral hemisphere in a glioblastoma mouse model
Matheus H W Crommentuijn, Sjoerd T T Schetters, Sophie A Dusoswa, Laura J W Kruijssen, Juan J Garcia-Vallejo, Yvette van Kooyk

Journal for ImmunoTherapy of Cancer Apr 2020, 8 (1) e000323; DOI: 10.1136/jitc-2019-000323
Involvement of the M-CSF/IL-34/CSF-1R pathway in malignant pleural mesothelioma
Thibaut Blondy, Sènan Mickael d'Almeida, Tina Briolay, Julie Tabiasco, Clément Meiller, Anne-Laure Chéné, Laurent Cellerin, Sophie Deshayes, Yves Delneste, Jean-François Fonteneau, Nicolas Boisgerault, Jaafar Bennouna, Marc Grégoire, Didier Jean, Christophe Blanquart

Journal for ImmunoTherapy of Cancer Jun 2020, 8 (1) e000182; DOI: 10.1136/jitc-2019-000182
Cancer cell-intrinsic expression of MHC II in lung cancer cell lines is actively restricted by MEK/ERK signaling and epigenetic mechanisms
Alexander J Neuwelt, Abigail K Kimball, Amber M Johnson, Benjamin W Arnold, Bonnie L Bullock, Rachael E Kaspar, Emily K Kleczko, Jeff W Kwak, Meng-Han Wu, Lynn E Heasley, Robert C Doebele, Howard Y Li, Raphael A Nemenoff, Eric T Clambey

Journal for ImmunoTherapy of Cancer Apr 2020, 8 (1) e000441; DOI: 10.1136/jitc-2019-000441
IL-6 promotes PD-L1 expression in monocytes and macrophages by decreasing protein tyrosine phosphatase receptor type O expression in human hepatocellular carcinoma
Wenjie Zhang, Yang Liu, Zhongyi Yan, Hui Yang, Wei Sun, Yongliang Yao, Yun Chen, Runqiu Jiang

Journal for ImmunoTherapy of Cancer Jun 2020, 8 (1) e000285; DOI: 10.1136/jitc-2019-000285
ALKS 4230: a novel engineered IL-2 fusion protein with an improved cellular selectivity profile for cancer immunotherapy
Jared E Lopes, Jan L Fisher, Heather L Flick, Chunhua Wang, Lei Sun, Marc S Ernstoff, Juan C Alvarez, Heather C Losey

Journal for ImmunoTherapy of Cancer Apr 2020, 8 (1) e000673; DOI: 10.1136/jitc-2020-000673

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