Basic Tumor Immunology

Endogenous TLR2 ligand embedded in the catalytic region of human cysteinyl-tRNA synthetase 1
Seongmin Cho, Sang Bum Kim, Youngjin Lee, Ee Chan Song, Uijoo Kim, Hyeong Yun Kim, Ji Hun Suh, Peter C Goughnour, YounHa Kim, Ina Yoon, Na Young Shin, Doyeun Kim, Il-Kyu Kim, Chang-Yuil Kang, Song Yee Jang, Myung Hee Kim, Sunghoon Kim

Journal for ImmunoTherapy of Cancer May 2020, 8 (1) e000277; DOI: 10.1136/jitc-2019-000277
High dose-rate brachytherapy of localized prostate cancer converts tumors from cold to hot
Simon P Keam, Heloise Halse, Thu Nguyen, Minyu Wang, Nicolas Van Kooten Losio, Catherine Mitchell, Franco Caramia, David J Byrne, Sue Haupt, Georgina Ryland, Phillip K Darcy, Shahneen Sandhu, Piers Blombery, Ygal Haupt, Scott G Williams, Paul J Neeson

Journal for ImmunoTherapy of Cancer Jun 2020, 8 (1) e000792; DOI: 10.1136/jitc-2020-000792
Multifaceted effects of soluble human CD6 in experimental cancer models
Inês T Simões, Fernando Aranda, Sergi Casadó-Llombart, María Velasco-de Andrés, Cristina Català, Pilar Álvarez, Marta Consuegra-Fernández, Marc Orta-Mascaró, Ramón Merino, Jesús Merino, José Alberola-Ila, Gloria González-Aseguinolaza, Esther Carreras, Vanesa Martínez, Francisco Lozano

Journal for ImmunoTherapy of Cancer Mar 2020, 8 (1) e000172; DOI: 10.1136/jitc-2019-000172
Tumor ablation plus co-administration of CpG and saponin adjuvants affects IL-1 production and multifunctional T cell numbers in tumor draining lymph nodes
Tonke K Raaijmakers, Renske J E van den Bijgaart, Martijn H den Brok, Melissa Wassink, Annemarie de Graaf, Jori A Wagenaars, Stefan Nierkens, Marleen Ansems, Gert Jan Scheffer, Gosse J Adema

Journal for ImmunoTherapy of Cancer May 2020, 8 (1) e000649; DOI: 10.1136/jitc-2020-000649
Involvement of the M-CSF/IL-34/CSF-1R pathway in malignant pleural mesothelioma
Thibaut Blondy, Sènan Mickael d'Almeida, Tina Briolay, Julie Tabiasco, Clément Meiller, Anne-Laure Chéné, Laurent Cellerin, Sophie Deshayes, Yves Delneste, Jean-François Fonteneau, Nicolas Boisgerault, Jaafar Bennouna, Marc Grégoire, Didier Jean, Christophe Blanquart

Journal for ImmunoTherapy of Cancer Jun 2020, 8 (1) e000182; DOI: 10.1136/jitc-2019-000182
Cellular cytotoxicity is a form of immunogenic cell death
Luna Minute, Alvaro Teijeira, Alfonso R Sanchez-Paulete, Maria C Ochoa, Maite Alvarez, Itziar Otano, Iñaki Etxeberrria, Elixabet Bolaños, Arantza Azpilikueta, Saray Garasa, Noelia Casares, Jose Luis Perez Gracia, Maria E Rodriguez-Ruiz, Pedro Berraondo, Ignacio Melero

Journal for ImmunoTherapy of Cancer Mar 2020, 8 (1) e000325; DOI: 10.1136/jitc-2019-000325
Neoantigen load and HLA-class I expression identify a subgroup of tumors with a T-cell-inflamed phenotype and favorable prognosis in homologous recombination-proficient high-grade serous ovarian carcinoma
Hirokazu Matsushita, Kosei Hasegawa, Katsutoshi Oda, Shogo Yamamoto, Kayo Asada, Takahiro Karasaki, Akira Yabuno, Akira Nishijima, Takahide Nejo, Yukari Kobayashi, Sho Sato, Yuji Ikeda, Manami Miyai, Yusuke Takahashi, Rui Yamaguchi, Keiichi Fujiwara, Hiroyuki Aburatani, Kazuhiro Kakimi

Journal for ImmunoTherapy of Cancer May 2020, 8 (1) e000375; DOI: 10.1136/jitc-2019-000375
IL-6 promotes PD-L1 expression in monocytes and macrophages by decreasing protein tyrosine phosphatase receptor type O expression in human hepatocellular carcinoma
Wenjie Zhang, Yang Liu, Zhongyi Yan, Hui Yang, Wei Sun, Yongliang Yao, Yun Chen, Runqiu Jiang

Journal for ImmunoTherapy of Cancer Jun 2020, 8 (1) e000285; DOI: 10.1136/jitc-2019-000285
EpCAM-high liver cancer stem cells resist natural killer cell–mediated cytotoxicity by upregulating CEACAM1
Dong Jun Park, Pil Soo Sung, Jung-Hee Kim, Gil Won Lee, Jeong Won Jang, Eun Sun Jung, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon

Journal for ImmunoTherapy of Cancer Mar 2020, 8 (1) e000301; DOI: 10.1136/jitc-2019-000301
Heterodimeric IL-15 delays tumor growth and promotes intratumoral CTL and dendritic cell accumulation by a cytokine network involving XCL1, IFN-γ, CXCL9 and CXCL10
Cristina Bergamaschi, Hrishikesh Pandit, Bethany A Nagy, Dimitris Stellas, Shawn M Jensen, Jenifer Bear, Maggie Cam, Antonio Valentin, Bernard A Fox, Barbara K Felber, George N Pavlakis

Journal for ImmunoTherapy of Cancer May 2020, 8 (1) e000599; DOI: 10.1136/jitc-2020-000599

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