Basic Tumor Immunology

Peptide vaccination directed against IDO1-expressing immune cells elicits CD8⁺ and CD4⁺ T-cell-mediated antitumor immunity and enhanced anti-PD1 responses
Souvik Dey, Erika Sutanto-Ward, Katharina L Kopp, James DuHadaway, Arpita Mondal, Dema Ghaban, Inés Lecoq, Mai-Britt Zocca, Lauren M F Merlo, Laura Mandik-Nayak, Mads Hald Andersen, Ayako Wakatsuki Pedersen, Alexander J Muller

Journal for ImmunoTherapy of Cancer Jul 2020, 8 (2) e000605; DOI: 10.1136/jitc-2020-000605
Interrogating the immune-modulating roles of radiation therapy for a rational combination with immune-checkpoint inhibitors in treating pancreatic cancer
Kenji Fujiwara, May Tun Saung, Hao Jing, Brian Herbst, MacKenzie Zarecki, Stephen Muth, Annie Wu, Elaine Bigelow, Linda Chen, Keyu Li, Neolle Jurcak, Alex B Blair, Ding Ding, Michael Wichroski, Jordan Blum, Nathan Cheadle, Jennifer Koenitzer, Lei Zheng

Journal for ImmunoTherapy of Cancer Jul 2020, 8 (2) e000351; DOI: 10.1136/jitc-2019-000351
Immunization associated with primary tumor growth leads to rejection of commonly used syngeneic tumors upon tumor rechallenge
Bruno Alicke, Klara Totpal, Jill M Schartner, Amy M Berkley, Sophie M Lehar, Aude-Hélène Capietto, Rafael A Cubas, Stephen E Gould

Journal for ImmunoTherapy of Cancer Jul 2020, 8 (2) e000532; DOI: 10.1136/jitc-2020-000532
Hematopoietic lineage-converted T cells carrying tumor-associated antigen-recognizing TCRs effectively kill tumor cells
Fangxiao Hu, Dehao Huang, Yuxuan Luo, Peiqing Zhou, Cui Lv, Kaitao Wang, Qitong Weng, Xiaofei Liu, Yuxian Guan, Yang Geng, Juan Du, Jiekai Chen, Jinyong Wang, Hongling Wu

Journal for ImmunoTherapy of Cancer Jul 2020, 8 (2) e000498; DOI: 10.1136/jitc-2019-000498
Fusion of the dendritic cell-targeting chemokine MIP3α to melanoma antigen Gp100 in a therapeutic DNA vaccine significantly enhances immunogenicity and survival in a mouse melanoma model
James T. Gordy, Kun Luo, Hong Zhang, Arya Biragyn, Richard B. Markham

Journal for ImmunoTherapy of Cancer Dec 2016, 4 (1) 96; DOI: 10.1186/s40425-016-0189-y
Classical and non-classical HLA class I aberrations in primary cervical squamous- and adenocarcinomas and paired lymph node metastases
Debbie M. Ferns, A. Marijne Heeren, Sanne Samuels, Maaike C. G. Bleeker, Tanja D. de Gruijl, Gemma G. Kenter, Ekaterina S. Jordanova

Journal for ImmunoTherapy of Cancer Dec 2016, 4 (1) 78; DOI: 10.1186/s40425-016-0184-3
Anti-PD-1 increases the clonality and activity of tumor infiltrating antigen specific T cells induced by a potent immune therapy consisting of vaccine and metronomic cyclophosphamide
Genevieve M. Weir, Olga Hrytsenko, Tara Quinton, Neil L. Berinstein, Marianne M. Stanford, Marc Mansour

Journal for ImmunoTherapy of Cancer Dec 2016, 4 (1) 68; DOI: 10.1186/s40425-016-0169-2
Adenosine-generating ovarian cancer cells attract myeloid cells which differentiate into adenosine-generating tumor associated macrophages – a self-amplifying, CD39- and CD73-dependent mechanism for tumor immune escape
Itsaso Montalbán del Barrio, Cornelia Penski, Laura Schlahsa, Roland G. Stein, Joachim Diessner, Achim Wöckel, Johannes Dietl, Manfred B. Lutz, Michel Mittelbronn, Jörg Wischhusen, Sebastian F. M. Häusler

Journal for ImmunoTherapy of Cancer Dec 2016, 4 (1) 49; DOI: 10.1186/s40425-016-0154-9
Pancreatic cancer stem cells in patient pancreatic xenografts are sensitive to drozitumab, an agonistic antibody against DR5
Jason W.-L. Eng, Thomas A. Mace, Rohit Sharma, Danielle Y. F. Twum, Peng Peng, John F. Gibbs, Rosemarie Pitoniak, Chelsey B. Reed, Scott I. Abrams, Elizabeth A. Repasky, Bonnie L. Hylander

Journal for ImmunoTherapy of Cancer Dec 2016, 4 (1) 33; DOI: 10.1186/s40425-016-0136-y

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