- Factors Influencing Clinically Meaningful Recanalization after IV-rtPA in Acute Ischemic Stroke
Predictors of clinically meaningful recanalization were assessed in 126 patients with acute anterior circulation stroke treated with IV thrombolysis. End points were CT angiographic recanalization and good clinical outcome at 90 days. Clinically meaningful recanalization occurred in 29% of patients, who had fewer neurologic deficits and higher ASPECTS at baseline. Admission NIHSS score and site of arterial occlusion were significant predictors of meaningful recanalization. Specifically, mild baseline deficits and distal vessel occlusions were significant predictors of clinically meaningful recanalization. A combination of these was better than either parameter alone.
- Efficacy and Safety of Flow Diversion for Paraclinoid Aneurysms: A Matched-Pair Analysis Compared with Standard Endovascular Approaches
These seasoned investigators sought to evaluate the efficacy and safety of flow-diverting devices for the treatment of complex paraclinoid aneurysms in 21 patients and compared their results with historical matched controls treated at their institution. Aneurysm size, location, risk factors, and comorbidities were equal for both groups. In the hands of these authors, flow diverters achieved a higher rate of aneurysm obliteration when compared with other treatments and did not show an increased rate of complications.
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