- Comparison of a Whole-Brain Contrast-Enhanced 3D TSE T1WI versus Orbits Contrast-Enhanced 2D Coronal T1WI at 3T MRI for the Detection of Optic Nerve Enhancement in Patients with Acute Loss of Visual Acuity
This retrospective, single-center study of 1023 patients presenting with acute loss of vision compared orbits contrast-enhanced 2D coronal T1WI with a whole-brain contrast-enhanced 3D TSE T1WI at 3T for the detection of optic nerve enhancement. The latter (WBCE-3D T1WI) demonstrated higher sensitivity and specificity in diagnosing optic neuritis, particularly in cases involving the canalicular segments.
- The Differentiation between Progressive Disease and Treatment-Induced Effects with Perfusion-Weighted Arterial Spin-Labeling in High-Grade Gliomas
In this retrospective, single-center cohort study, 141 patients (173 lesions) with a new or increasing contrast-enhancing lesion after radiotherapy with or without chemotherapy were assessed with ASL perfusion. Although ASL performed poorly in differentiating progressive disease from treatment-induced effects in high-grade gliomas within 6 months after radiation therapy, it showed fair performance after this period.
- MR Imaging Features of Critical Spinal Demyelinating Lesions Associated with Progressive Motor Impairment
This retrospective, observational MRI study compared spinal cord critical demyelinating lesions anatomically associated with progressive motor impairment with any additional “noncritical” spinal cord demyelinating lesions. MRI characteristics that favored critical spinal cord demyelinating lesions included moderate-to-severe, focal, lesion-associated spinal cord atrophy; lateral column axial location; central region; ventral column; and larger lesion size. In particular, the presence of focal, lesion-associated atrophy, lateral column axial location, and larger lesion size may be associated with the development of progressive motor impairment in MS.
AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates