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This retrospective multi-institution cohort study analyzed the temporal features of CSF-venous fistula (CVF) visualization on dynamic decubitus CT myelography (dCTM) in 48 patients. The results showed that most CVFs were visible on first or subsequent phases of dCTM, but approximately 1 in 8 were only visible on either the early or delayed phase. The authors conclude that acquiring greater than 1 phase of imaging increases the sensitivity of dCTM by increasing its temporal resolution.

The purpose of this study was to determine whether reformatted laryngeal images derived from a standard neck CT acquisition can replace a separate dedicated high-resolution laryngeal acquisition. In 200 patients, the authors found a discrepancy in nearly one-quarter of the interpretations. Both up-staging and down-staging errors were made with the standard neck CT protocol and were critical in defining the optimal therapeutic approach. The authors concluded that the addition of focused images of the larynx after a second contrast bolus and a second acquisition sequence improves the radiologic staging of laryngeal tumors.

The therapeutic use of monoclonal antibodies is rapidly expanding for a variety of diseases. This review article describes commonly used monoclonal antibody-targeted therapeutic agents, their mechanism of action, clinical applications, and major adverse events with a focus on neurologic and neuroimaging manifestations. For example, immunostimulating anticancer mAbs can lead to proinflammatory conditions, while immunosuppressive medications can lead to activation of underlying opportunistic infections. Amyloid-segregating mAbs can lead to amyloid-related imaging abnormalities, and TNF-inhibiting mAbs have a higher incidence of demyelinating abnormalities.