- CT of the Larynx: Is an Additional High-Resolution Acquisition Necessary for Diagnostic Accuracy?
The purpose of this study was to determine whether reformatted laryngeal images derived from a standard neck CT acquisition can replace a separate dedicated high-resolution laryngeal acquisition. In 200 patients, the authors found a discrepancy in nearly one-quarter of the interpretations. Both up-staging and down-staging errors were made with the standard neck CT protocol and were critical in defining the optimal therapeutic approach. The authors concluded that the addition of focused images of the larynx after a second contrast bolus and a second acquisition sequence improves the radiologic staging of laryngeal tumors.
- Monoclonal Antibodies: What the Diagnostic Neuroradiologist Needs to Know
The therapeutic use of monoclonal antibodies is rapidly expanding for a variety of diseases. This review article describes commonly used monoclonal antibody-targeted therapeutic agents, their mechanism of action, clinical applications, and major adverse events with a focus on neurologic and neuroimaging manifestations. For example, immunostimulating anticancer mAbs can lead to proinflammatory conditions, while immunosuppressive medications can lead to activation of underlying opportunistic infections. Amyloid-segregating mAbs can lead to amyloid-related imaging abnormalities, and TNF-inhibiting mAbs have a higher incidence of demyelinating abnormalities.
- Prevalence of Cochlear-Facial and Other Non-Superior Semicircular Canal Third Window Dehiscence on High-Resolution Temporal Bone CT
This study of 500 patients found the prevalence of non-SSCD on high-resolution CT in asymptomatic individuals to be 1.6% for CFD and 8.0% for JVD as compared with the rate in patients with audiologic or vestibular symptoms (2.9% for CFD and 7.8% for JVD). There was no statistically significant difference in the rates of radiologic findings between patients with reported symptoms suggestive of a possible third window syndrome and those without auditory or vestibular symptoms.
- DWI-Detected Ischemic Lesions after Endovascular Treatment for Cerebral Aneurysms: An Updated Systematic Review and Meta-analysis
This systematic review and meta-analysis found the incidence of new postprocedural DWI-detected ischemic lesions after endovascular treatment for intracranial aneurysms to be 47.0% (95% CI, 39.6%–55.8%), regardless of the endovascular procedure used. Studies have shown that almost half of these lesions are asymptomatic, and if small (<5 mm), these lesions have been shown to regress without negative effect on clinical outcome.
- Factors Predictive of Treatment Success in CT-Guided Fibrin Occlusion of CSF-Venous Fistulas: A Multicenter Retrospective Cross-Sectional Study
Multi-institutional retrospective evaluation of patients with CSF-to-venous fistulas treated with CT-guided fibrin glue treatment showed that treatment success may be in part driven by whether the spread of fibrin injectate matches the target drainage pathway of the CVF.
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