Immunotherapy

Induction of EBV latent membrane protein-2A (LMP2A)-specific T cells and construction of individualized TCR-engineered T cells for EBV-associated malignancies
Chaoting Zhang, Qin Tan, Shance Li, Luyan Shen, Jingtao Zhang, Ying Liu, Wenjun Yang, Zheming Lu

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002516; DOI: 10.1136/jitc-2021-002516
Clinical outcomes of patients with corticosteroid refractory immune checkpoint inhibitor-induced enterocolitis treated with infliximab
James L Alexander, Hajir Ibraheim, Bhavisha Sheth, Jessica Little, Muhammad Saheb Khan, Camellia Richards, Nikki Hunter, Dharmisha Chauhan, Raguprakash Ratnakumaran, Kathleen McHugh, David J Pinato, Paul Nathan, Julia Choy, Shanthini M Crusz, Andrew Furness, Samra Turajlic, Lisa Pickering, James Larkin, Julian P Teare, Sophie Papa, Ally Speight, Anand Sharma, Nick Powell

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002742; DOI: 10.1136/jitc-2021-002742
GCH1 induces immunosuppression through metabolic reprogramming and IDO1 upregulation in triple-negative breast cancer
Jin-Li Wei, Si-Yu Wu, Yun-Song Yang, Yi Xiao, Xi Jin, Xiao-En Xu, Xin Hu, Da-Qiang Li, Yi-Zhou Jiang, Zhi-Ming Shao

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002383; DOI: 10.1136/jitc-2021-002383
Direct identification of neoantigen-specific TCRs from tumor specimens by high-throughput single-cell sequencing
Yong-Chen Lu, Zhili Zheng, Frank J Lowery, Jared J Gartner, Todd D Prickett, Paul F Robbins, Steven A Rosenberg

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002595; DOI: 10.1136/jitc-2021-002595
Not all hematopoietic growth factors are created equal: should we gain information for their use with immunotherapy?
Paolo Bossi, Cristina Gurizzan, Luigi Lorini, Pierluigi di Mauro, Chiara Sardini, Marco Merlano

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e003154; DOI: 10.1136/jitc-2021-003154
Clinical efficacy of T-cell therapy after short-term BRAF-inhibitor priming in patients with checkpoint inhibitor-resistant metastatic melanoma
Troels Holz Borch, Katja Harbst, Aynal Haque Rana, Rikke Andersen, Evelina Martinenaite, Per Kongsted, Magnus Pedersen, Morten Nielsen, Julie Westerlin Kjeldsen, Anders Handrup Kverneland, Martin Lauss, Lisbet Rosenkrantz Hölmich, Helle Hendel, Özcan Met, Göran Jönsson, Marco Donia, Inge Marie Svane

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002703; DOI: 10.1136/jitc-2021-002703
Exploiting off-target effects of estrogen deprivation to sensitize estrogen receptor negative breast cancer to immune killing
Benjamin Wolfson, Michelle R Padget, Jeffrey Schlom, James W Hodge

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002258; DOI: 10.1136/jitc-2020-002258
DNA methylation-based prediction of response to immune checkpoint inhibition in metastatic melanoma
Katharina Filipski, Michael Scherer, Kim N. Zeiner, Andreas Bucher, Johannes Kleemann, Philipp Jurmeister, Tabea I. Hartung, Markus Meissner, Karl H. Plate, Tim R. Fenton, Jörn Walter, Sascha Tierling, Bastian Schilling, Pia S. Zeiner, Patrick N. Harter

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002226; DOI: 10.1136/jitc-2020-002226
It’s not ‘just a tube of blood’: principles of protocol development, sample collection, staffing and budget considerations for blood-based biomarkers in immunotherapy studies
Cindy Y Jiang, Zeqi Niu, Michael D Green, Lili Zhao, Shelby Raupp, Brittany Pannecouk, Dean E Brenner, Sunitha Nagrath, Nithya Ramnath

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e003212; DOI: 10.1136/jitc-2021-003212
Reversal of immune-checkpoint inhibitor fulminant myocarditis using personalized-dose-adjusted abatacept and ruxolitinib: proof of concept
Lee S Nguyen, Marie Bretagne, Jennifer Arrondeau, Noel Zahr, Stephane Ederhy, Baptiste Abbar, Bruno Pinna, Yves Allenbach, Jean-Paul Mira, Javid Moslehi, Michelle Rosenzwajg, Joe-Elie Salem

Journal for ImmunoTherapy of Cancer Apr 2022, 10 (4) e004699; DOI: 10.1136/jitc-2022-004699

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