Immunotherapy

Neoadjuvant immunotherapy of locoregionally advanced solid tumors
Ahmad A Tarhini, Jennifer R Eads, Kathleen N Moore, Valerie Tatard-Leitman, John Wright, Patrick M Forde, Robert L Ferris

Journal for ImmunoTherapy of Cancer Aug 2022, 10 (8) e005036; DOI: 10.1136/jitc-2022-005036
Safety, tolerability and efficacy of agonist anti-CD27 antibody (varlilumab) administered in combination with anti-PD-1 (nivolumab) in advanced solid tumors
Rachel E Sanborn, Michael J Pishvaian, Margaret K Callahan, Amy Weise, Branimir I Sikic, Osama Rahma, Daniel C Cho, Naiyer A Rizvi, Mario Sznol, Jose Lutzky, Julie E Bauman, Rhonda L Bitting, Alexander Starodub, Antonio Jimeno, David A Reardon, Thomas Kaley, Fabio Iwamoto, Joachim M Baehring, Deepa S Subramaniam, Jeanny B Aragon-Ching, Thomas R Hawthorne, Tracey Rawls, Michael Yellin, Tibor Keler

Journal for ImmunoTherapy of Cancer Aug 2022, 10 (8) e005147; DOI: 10.1136/jitc-2022-005147
Local anesthetics elicit immune-dependent anticancer effects
Lucillia Bezu, Alejandra Wu Chuang, Allan Sauvat, Juliette Humeau, Wei Xie, Giulia Cerrato, Peng Liu, Liwei Zhao, Shuai Zhang, Julie Le Naour, Jonathan Pol, Peter van Endert, Oliver Kepp, Fabrice Barlesi, Guido Kroemer

Journal for ImmunoTherapy of Cancer Apr 2022, 10 (4) e004151; DOI: 10.1136/jitc-2021-004151
Small extracellular vesicles induce resistance to anti-GD2 immunotherapy unveiling tipifarnib as an adjunct to neuroblastoma immunotherapy
Xiaoming Liu, Carson A Wills, Longgui Chen, Jiawen Zhang, Yuanjun Zhao, Mi Zhou, Jeffrey M Sundstrom, Todd Schell, Vladimir S Spiegelman, Megan M Young, Hong-Gang Wang

Journal for ImmunoTherapy of Cancer Apr 2022, 10 (4) e004399; DOI: 10.1136/jitc-2021-004399
High levels of chromosomal aberrations negatively associate with benefit to checkpoint inhibition in NSCLC
Joan Frigola, Caterina Carbonell, Patricia Iranzo, Nuria Pardo, Ana Callejo, Susana Cedres, Alex Martinez-Marti, Alejandro Navarro, Mireia Soleda, Jose Jimenez, Javier Hernandez-Losa, Ana Vivancos, Enriqueta Felip, Ramon Amat

Journal for ImmunoTherapy of Cancer Apr 2022, 10 (4) e004197; DOI: 10.1136/jitc-2021-004197
Molecular imaging to support cancer immunotherapy
Pim P van de Donk, Sjoukje F Oosting, Daan G Knapen, Anthonie J van der Wekken, Adrienne H Brouwers, Marjolijn N Lub-de Hooge, Derk-Jan A de Groot, Elisabeth GE de Vries

Journal for ImmunoTherapy of Cancer Aug 2022, 10 (8) e004949; DOI: 10.1136/jitc-2022-004949
Neutrophils in the era of immune checkpoint blockade
Julien Faget, Solange Peters, Xavier Quantin, Etienne Meylan, Nathalie Bonnefoy

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002242; DOI: 10.1136/jitc-2020-002242
WDR5-H3K4me3 epigenetic axis regulates OPN expression to compensate PD-L1 function to promote pancreatic cancer immune escape
Chunwan Lu, Zhuoqi Liu, John D Klement, Dafeng Yang, Alyssa D Merting, Dakota Poschel, Thomas Albers, Jennifer L Waller, Huidong Shi, Kebin Liu

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002624; DOI: 10.1136/jitc-2021-002624
VEGFR-2 redirected CAR-T cells are functionally impaired by soluble VEGF-A competition for receptor binding
Evripidis Lanitis, Paris Kosti, Catherine Ronet, Elisabetta Cribioli, Giorgia Rota, Aodrenn Spill, Patrick Reichenbach, Vincent Zoete, Denarda Dangaj Laniti, George Coukos, Melita Irving

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e002151; DOI: 10.1136/jitc-2020-002151
STING agonist loaded lipid nanoparticles overcome anti-PD-1 resistance in melanoma lung metastasis via NK cell activation
Takashi Nakamura, Takanori Sato, Rikito Endo, Shun Sasaki, Naomichi Takahashi, Yusuke Sato, Mamoru Hyodo, Yoshihiro Hayakawa, Hideyoshi Harashima

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002852; DOI: 10.1136/jitc-2021-002852

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