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Research ArticleORIGINAL RESEARCH

Implications of Hydrocephalus on [18F]-Fluorodeoxyglucose Positron Emission Tomography Statistical Parametric Mapping Analysis in Neurodegenerative Disease Evaluation

Andres Ricaurte-Fajardo, Ana M. Franceschi, Debra D’ Angelo, Aliah McCalla, Miran Salgado, Moath Hamed, Brielle Intorcia, Carlyn Wisherop, Samantha A. Keil, Anna S. Nordvig, Joseph R. Osborne, Gloria C. Chiang and Jana Ivanidze
American Journal of Neuroradiology February 2025, ajnr.A8698; DOI: https://doi.org/10.3174/ajnr.A8698
Andres Ricaurte-Fajardo
From the Department of Radiology (A.R-F, A.M, B.I, C.W, SA.K, JR.O, GC.C, J.I), Weill Cornell Medicine, New York Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Division of Molecular Imaging and Therapeutics (A.R-F, JR.O, J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Brain Health Imaging Institute (A.R-F, SA.K, AS.N, GC.C and J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Neuroscience, Division of Neurology (A.R-F), Pontificia Universidad Javeriana, Bogota, Colombia; the Department of Radiology (AM.F) Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwel, New York, New York, USA; the Department of Population Health Sciences (D.D) Weill Cornell Medicine, New York, New York, USA; the School of Medicine (A.M) Central Michigan College of Medicine, Saginaw, Michigan, USA; the Department of Neurology (M.S, M.H) New York Presbyterian Brooklyn Methodist Hospital, New York, USA; the Department of Neurology (AS.N) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA
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Ana M. Franceschi
From the Department of Radiology (A.R-F, A.M, B.I, C.W, SA.K, JR.O, GC.C, J.I), Weill Cornell Medicine, New York Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Division of Molecular Imaging and Therapeutics (A.R-F, JR.O, J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Brain Health Imaging Institute (A.R-F, SA.K, AS.N, GC.C and J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Neuroscience, Division of Neurology (A.R-F), Pontificia Universidad Javeriana, Bogota, Colombia; the Department of Radiology (AM.F) Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwel, New York, New York, USA; the Department of Population Health Sciences (D.D) Weill Cornell Medicine, New York, New York, USA; the School of Medicine (A.M) Central Michigan College of Medicine, Saginaw, Michigan, USA; the Department of Neurology (M.S, M.H) New York Presbyterian Brooklyn Methodist Hospital, New York, USA; the Department of Neurology (AS.N) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA
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Debra D’ Angelo
From the Department of Radiology (A.R-F, A.M, B.I, C.W, SA.K, JR.O, GC.C, J.I), Weill Cornell Medicine, New York Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Division of Molecular Imaging and Therapeutics (A.R-F, JR.O, J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Brain Health Imaging Institute (A.R-F, SA.K, AS.N, GC.C and J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Neuroscience, Division of Neurology (A.R-F), Pontificia Universidad Javeriana, Bogota, Colombia; the Department of Radiology (AM.F) Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwel, New York, New York, USA; the Department of Population Health Sciences (D.D) Weill Cornell Medicine, New York, New York, USA; the School of Medicine (A.M) Central Michigan College of Medicine, Saginaw, Michigan, USA; the Department of Neurology (M.S, M.H) New York Presbyterian Brooklyn Methodist Hospital, New York, USA; the Department of Neurology (AS.N) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA
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Aliah McCalla
From the Department of Radiology (A.R-F, A.M, B.I, C.W, SA.K, JR.O, GC.C, J.I), Weill Cornell Medicine, New York Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Division of Molecular Imaging and Therapeutics (A.R-F, JR.O, J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Brain Health Imaging Institute (A.R-F, SA.K, AS.N, GC.C and J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Neuroscience, Division of Neurology (A.R-F), Pontificia Universidad Javeriana, Bogota, Colombia; the Department of Radiology (AM.F) Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwel, New York, New York, USA; the Department of Population Health Sciences (D.D) Weill Cornell Medicine, New York, New York, USA; the School of Medicine (A.M) Central Michigan College of Medicine, Saginaw, Michigan, USA; the Department of Neurology (M.S, M.H) New York Presbyterian Brooklyn Methodist Hospital, New York, USA; the Department of Neurology (AS.N) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA
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Miran Salgado
From the Department of Radiology (A.R-F, A.M, B.I, C.W, SA.K, JR.O, GC.C, J.I), Weill Cornell Medicine, New York Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Division of Molecular Imaging and Therapeutics (A.R-F, JR.O, J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Brain Health Imaging Institute (A.R-F, SA.K, AS.N, GC.C and J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Neuroscience, Division of Neurology (A.R-F), Pontificia Universidad Javeriana, Bogota, Colombia; the Department of Radiology (AM.F) Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwel, New York, New York, USA; the Department of Population Health Sciences (D.D) Weill Cornell Medicine, New York, New York, USA; the School of Medicine (A.M) Central Michigan College of Medicine, Saginaw, Michigan, USA; the Department of Neurology (M.S, M.H) New York Presbyterian Brooklyn Methodist Hospital, New York, USA; the Department of Neurology (AS.N) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA
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Moath Hamed
From the Department of Radiology (A.R-F, A.M, B.I, C.W, SA.K, JR.O, GC.C, J.I), Weill Cornell Medicine, New York Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Division of Molecular Imaging and Therapeutics (A.R-F, JR.O, J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Brain Health Imaging Institute (A.R-F, SA.K, AS.N, GC.C and J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Neuroscience, Division of Neurology (A.R-F), Pontificia Universidad Javeriana, Bogota, Colombia; the Department of Radiology (AM.F) Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwel, New York, New York, USA; the Department of Population Health Sciences (D.D) Weill Cornell Medicine, New York, New York, USA; the School of Medicine (A.M) Central Michigan College of Medicine, Saginaw, Michigan, USA; the Department of Neurology (M.S, M.H) New York Presbyterian Brooklyn Methodist Hospital, New York, USA; the Department of Neurology (AS.N) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA
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Brielle Intorcia
From the Department of Radiology (A.R-F, A.M, B.I, C.W, SA.K, JR.O, GC.C, J.I), Weill Cornell Medicine, New York Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Division of Molecular Imaging and Therapeutics (A.R-F, JR.O, J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Brain Health Imaging Institute (A.R-F, SA.K, AS.N, GC.C and J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Neuroscience, Division of Neurology (A.R-F), Pontificia Universidad Javeriana, Bogota, Colombia; the Department of Radiology (AM.F) Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwel, New York, New York, USA; the Department of Population Health Sciences (D.D) Weill Cornell Medicine, New York, New York, USA; the School of Medicine (A.M) Central Michigan College of Medicine, Saginaw, Michigan, USA; the Department of Neurology (M.S, M.H) New York Presbyterian Brooklyn Methodist Hospital, New York, USA; the Department of Neurology (AS.N) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA
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Carlyn Wisherop
From the Department of Radiology (A.R-F, A.M, B.I, C.W, SA.K, JR.O, GC.C, J.I), Weill Cornell Medicine, New York Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Division of Molecular Imaging and Therapeutics (A.R-F, JR.O, J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Brain Health Imaging Institute (A.R-F, SA.K, AS.N, GC.C and J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Neuroscience, Division of Neurology (A.R-F), Pontificia Universidad Javeriana, Bogota, Colombia; the Department of Radiology (AM.F) Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwel, New York, New York, USA; the Department of Population Health Sciences (D.D) Weill Cornell Medicine, New York, New York, USA; the School of Medicine (A.M) Central Michigan College of Medicine, Saginaw, Michigan, USA; the Department of Neurology (M.S, M.H) New York Presbyterian Brooklyn Methodist Hospital, New York, USA; the Department of Neurology (AS.N) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA
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Samantha A. Keil
From the Department of Radiology (A.R-F, A.M, B.I, C.W, SA.K, JR.O, GC.C, J.I), Weill Cornell Medicine, New York Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Division of Molecular Imaging and Therapeutics (A.R-F, JR.O, J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Brain Health Imaging Institute (A.R-F, SA.K, AS.N, GC.C and J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Neuroscience, Division of Neurology (A.R-F), Pontificia Universidad Javeriana, Bogota, Colombia; the Department of Radiology (AM.F) Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwel, New York, New York, USA; the Department of Population Health Sciences (D.D) Weill Cornell Medicine, New York, New York, USA; the School of Medicine (A.M) Central Michigan College of Medicine, Saginaw, Michigan, USA; the Department of Neurology (M.S, M.H) New York Presbyterian Brooklyn Methodist Hospital, New York, USA; the Department of Neurology (AS.N) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA
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Anna S. Nordvig
From the Department of Radiology (A.R-F, A.M, B.I, C.W, SA.K, JR.O, GC.C, J.I), Weill Cornell Medicine, New York Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Division of Molecular Imaging and Therapeutics (A.R-F, JR.O, J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Brain Health Imaging Institute (A.R-F, SA.K, AS.N, GC.C and J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Neuroscience, Division of Neurology (A.R-F), Pontificia Universidad Javeriana, Bogota, Colombia; the Department of Radiology (AM.F) Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwel, New York, New York, USA; the Department of Population Health Sciences (D.D) Weill Cornell Medicine, New York, New York, USA; the School of Medicine (A.M) Central Michigan College of Medicine, Saginaw, Michigan, USA; the Department of Neurology (M.S, M.H) New York Presbyterian Brooklyn Methodist Hospital, New York, USA; the Department of Neurology (AS.N) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA
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Joseph R. Osborne
From the Department of Radiology (A.R-F, A.M, B.I, C.W, SA.K, JR.O, GC.C, J.I), Weill Cornell Medicine, New York Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Division of Molecular Imaging and Therapeutics (A.R-F, JR.O, J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Brain Health Imaging Institute (A.R-F, SA.K, AS.N, GC.C and J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Neuroscience, Division of Neurology (A.R-F), Pontificia Universidad Javeriana, Bogota, Colombia; the Department of Radiology (AM.F) Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwel, New York, New York, USA; the Department of Population Health Sciences (D.D) Weill Cornell Medicine, New York, New York, USA; the School of Medicine (A.M) Central Michigan College of Medicine, Saginaw, Michigan, USA; the Department of Neurology (M.S, M.H) New York Presbyterian Brooklyn Methodist Hospital, New York, USA; the Department of Neurology (AS.N) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA
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Gloria C. Chiang
From the Department of Radiology (A.R-F, A.M, B.I, C.W, SA.K, JR.O, GC.C, J.I), Weill Cornell Medicine, New York Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Division of Molecular Imaging and Therapeutics (A.R-F, JR.O, J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Brain Health Imaging Institute (A.R-F, SA.K, AS.N, GC.C and J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Neuroscience, Division of Neurology (A.R-F), Pontificia Universidad Javeriana, Bogota, Colombia; the Department of Radiology (AM.F) Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwel, New York, New York, USA; the Department of Population Health Sciences (D.D) Weill Cornell Medicine, New York, New York, USA; the School of Medicine (A.M) Central Michigan College of Medicine, Saginaw, Michigan, USA; the Department of Neurology (M.S, M.H) New York Presbyterian Brooklyn Methodist Hospital, New York, USA; the Department of Neurology (AS.N) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA
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Jana Ivanidze
From the Department of Radiology (A.R-F, A.M, B.I, C.W, SA.K, JR.O, GC.C, J.I), Weill Cornell Medicine, New York Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Division of Molecular Imaging and Therapeutics (A.R-F, JR.O, J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Brain Health Imaging Institute (A.R-F, SA.K, AS.N, GC.C and J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Neuroscience, Division of Neurology (A.R-F), Pontificia Universidad Javeriana, Bogota, Colombia; the Department of Radiology (AM.F) Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwel, New York, New York, USA; the Department of Population Health Sciences (D.D) Weill Cornell Medicine, New York, New York, USA; the School of Medicine (A.M) Central Michigan College of Medicine, Saginaw, Michigan, USA; the Department of Neurology (M.S, M.H) New York Presbyterian Brooklyn Methodist Hospital, New York, USA; the Department of Neurology (AS.N) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA
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Article Information

ajnr.A8698
DOI 
https://doi.org/10.3174/ajnr.A8698
PubMed 
39947683

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Published online February 13, 2025.

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  • You are currently viewing a Latest version of this article (February 13, 2025 - 06:41).
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Copyright & Usage 
© 2025 by American Journal of Neuroradiology

Author Information

  1. Andres Ricaurte-Fajardo,
  2. Ana M. Franceschi,
  3. Debra D’ Angelo,
  4. Aliah McCalla,
  5. Miran Salgado,
  6. Moath Hamed,
  7. Brielle Intorcia,
  8. Carlyn Wisherop,
  9. Samantha A. Keil,
  10. Anna S. Nordvig,
  11. Joseph R. Osborne,
  12. Gloria C. Chiang and
  13. Jana Ivanidze
  1. From the Department of Radiology (A.R-F, A.M, B.I, C.W, SA.K, JR.O, GC.C, J.I), Weill Cornell Medicine, New York Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Division of Molecular Imaging and Therapeutics (A.R-F, JR.O, J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Radiology, Brain Health Imaging Institute (A.R-F, SA.K, AS.N, GC.C and J.I) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA; the Department of Neuroscience, Division of Neurology (A.R-F), Pontificia Universidad Javeriana, Bogota, Colombia; the Department of Radiology (AM.F) Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwel, New York, New York, USA; the Department of Population Health Sciences (D.D) Weill Cornell Medicine, New York, New York, USA; the School of Medicine (A.M) Central Michigan College of Medicine, Saginaw, Michigan, USA; the Department of Neurology (M.S, M.H) New York Presbyterian Brooklyn Methodist Hospital, New York, USA; the Department of Neurology (AS.N) Weill Cornell Medicine, New York-Presbyterian Hospital, New York, New York, USA
  1. Correspondence to:
    Jana Ivanidze, MD, PhD. Department of Radiology, Weill Cornell Medicine, 1300 York Avenue, New York, New York, 10021, USA, jai9018{at}med.cornell.edu

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Implications of Hydrocephalus on [18F]-Fluorodeoxyglucose Positron Emission Tomography Statistical Parametric Mapping Analysis in Neurodegenerative Disease Evaluation
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Andres Ricaurte-Fajardo, Ana M. Franceschi, Debra D’ Angelo, Aliah McCalla, Miran Salgado, Moath Hamed, Brielle Intorcia, Carlyn Wisherop, Samantha A. Keil, Anna S. Nordvig, Joseph R. Osborne, Gloria C. Chiang, Jana Ivanidze
Implications of Hydrocephalus on [18F]-Fluorodeoxyglucose Positron Emission Tomography Statistical Parametric Mapping Analysis in Neurodegenerative Disease Evaluation
American Journal of Neuroradiology Feb 2025, ajnr.A8698; DOI: 10.3174/ajnr.A8698

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Accepted Manuscript
Implications of Hydrocephalus on [18F]-Fluorodeoxyglucose Positron Emission Tomography Statistical Parametric Mapping Analysis in Neurodegenerative Disease Evaluation
Andres Ricaurte-Fajardo, Ana M. Franceschi, Debra D’ Angelo, Aliah McCalla, Miran Salgado, Moath Hamed, Brielle Intorcia, Carlyn Wisherop, Samantha A. Keil, Anna S. Nordvig, Joseph R. Osborne, Gloria C. Chiang, Jana Ivanidze
American Journal of Neuroradiology Feb 2025, ajnr.A8698; DOI: 10.3174/ajnr.A8698
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