Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleNEUROINTERVENTION

Lesion-Filling Index from Quantitative DSA Correlates with Hemorrhage of Cerebral AVM

Ruinan Li, Yu Chen, Pingting Chen, Li Ma, Heze Han, Zhipeng Li, Wanting Zhou, Xiaolin Chen and Yuanli Zhao
American Journal of Neuroradiology May 2024, DOI: https://doi.org/10.3174/ajnr.A8218
Ruinan Li
aFrom the Department of Neurosurgery (R.L., Y.C., L.M., H.H., Z.L., X.C., Y.Z.), Beijing Tiantan Hospital, Capital Medical University, Beijing, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Ruinan Li
Yu Chen
aFrom the Department of Neurosurgery (R.L., Y.C., L.M., H.H., Z.L., X.C., Y.Z.), Beijing Tiantan Hospital, Capital Medical University, Beijing, China
bChina National Clinical Research Center for Neurological Diseases (Y.C., X.C., Y.Z.), Beijing, China
cBeijing Neurosurgical Institute (Y.C., X.C., Y.Z.), Beijing Tiantan Hospital, Capital Medical University, Beijing, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Yu Chen
Pingting Chen
dCollege of Energy and Power Engineering (P.C.), Nanjing University of Aeronautics and Astronautics, Nanjing, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Li Ma
aFrom the Department of Neurosurgery (R.L., Y.C., L.M., H.H., Z.L., X.C., Y.Z.), Beijing Tiantan Hospital, Capital Medical University, Beijing, China
eDepartment of Neurological Surgery (L.M.), University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Li Ma
Heze Han
aFrom the Department of Neurosurgery (R.L., Y.C., L.M., H.H., Z.L., X.C., Y.Z.), Beijing Tiantan Hospital, Capital Medical University, Beijing, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Zhipeng Li
aFrom the Department of Neurosurgery (R.L., Y.C., L.M., H.H., Z.L., X.C., Y.Z.), Beijing Tiantan Hospital, Capital Medical University, Beijing, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Wanting Zhou
fDepartment of Artificial Intelligence (W.Z.), Beijing University of Posts and Telecommunications, Beijing, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Xiaolin Chen
aFrom the Department of Neurosurgery (R.L., Y.C., L.M., H.H., Z.L., X.C., Y.Z.), Beijing Tiantan Hospital, Capital Medical University, Beijing, China
bChina National Clinical Research Center for Neurological Diseases (Y.C., X.C., Y.Z.), Beijing, China
cBeijing Neurosurgical Institute (Y.C., X.C., Y.Z.), Beijing Tiantan Hospital, Capital Medical University, Beijing, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yuanli Zhao
aFrom the Department of Neurosurgery (R.L., Y.C., L.M., H.H., Z.L., X.C., Y.Z.), Beijing Tiantan Hospital, Capital Medical University, Beijing, China
bChina National Clinical Research Center for Neurological Diseases (Y.C., X.C., Y.Z.), Beijing, China
cBeijing Neurosurgical Institute (Y.C., X.C., Y.Z.), Beijing Tiantan Hospital, Capital Medical University, Beijing, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Yuanli Zhao
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Abecassis IJ,
    2. Xu DS,
    3. Batjer HH, et al
    . Natural history of brain arteriovenous malformations: a systematic review. Neurosurg Focus 2014;37:E7 doi:10.3171/2014.6.FOCUS14250 pmid:25175445
    CrossRefPubMed
  2. 2.↵
    1. Rutledge C,
    2. Cooke DL,
    3. Hetts SW, et al
    . Brain arteriovenous malformations. Handb Clin Neurol 2021;176:171–78 doi:10.1016/B978-0-444-64034-5.00020-1 pmid:33272394
    CrossRefPubMed
  3. 3.↵
    1. Spetzler RF,
    2. Hargraves RW,
    3. McCormick PW, et al
    . Relationship of perfusion pressure and size to risk of hemorrhage from arteriovenous malformations. J Neurosurg 1992;76:918–23 doi:10.3171/jns.1992.76.6.0918 pmid:1588424
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Stapf C,
    2. Mast H,
    3. Sciacca RR, et al
    . Predictors of hemorrhage in patients with untreated brain arteriovenous malformation. Neurology 2006;66:1350–55 doi:10.1212/01.wnl.0000210524.68507.87 pmid:16682666
    CrossRefPubMed
  5. 5.↵
    1. Burkhardt JK,
    2. Chen X,
    3. Winkler EA, et al
    . Delayed venous drainage in ruptured arteriovenous malformations based on quantitative color-coded digital subtraction angiography. World Neurosurg 2017;104:619–27 doi:10.1016/j.wneu.2017.04.120 pmid:28457930
    CrossRefPubMed
  6. 6.↵
    1. Chen Y,
    2. Chen P,
    3. Li R, et al
    . Rupture-related quantitative hemodynamics of the supratentorial arteriovenous malformation nidus. J Neurosurg 2023;138:740–49 doi:10.3171/2022.6.JNS212818 pmid:35962966
    CrossRefPubMed
  7. 7.↵
    1. Li Z,
    2. Chen Y,
    3. Chen P, et al
    . Quantitative evaluation of hemodynamics after partial embolization of brain arteriovenous malformations. J Neurointerv Surg 2021;14:1112–17 doi:10.1136/neurintsurg-2021-018187 pmid:34872987
    Abstract/FREE Full Text
  8. 8.↵
    1. Hu YS,
    2. Lee CC,
    3. Wu HM, et al
    . Stagnant venous outflow predicts brain arteriovenous malformation obliteration after gamma knife radiosurgery without prior intervention. Neurosurgery 2020;87:338–47 doi:10.1093/neuros/nyz507 pmid:31792505
    CrossRefPubMed
  9. 9.↵
    1. Lin TM,
    2. Yang HC,
    3. Lee CC, et al
    . Stasis index from hemodynamic analysis using quantitative DSA correlates with hemorrhage of supratentorial arteriovenous malformation: a cross-sectional study. J Neurosurg 2019;132:1574–82 doi:10.3171/2019.1.JNS183386 pmid:31026828
    CrossRefPubMed
  10. 10.↵
    1. Lin CJ,
    2. Chen KK,
    3. Hu YS, et al
    . Quantified flow and angioarchitecture show similar associations with hemorrhagic presentation of brain arteriovenous malformations. J Neuroradiol 2023;50:79–85 doi:10.1016/j.neurad.2022.01.061 pmid:35120975
    CrossRefPubMed
  11. 11.↵
    1. Chen X,
    2. Cooke DL,
    3. Saloner D, et al
    . Higher flow is present in unruptured arteriovenous malformations with silent intralesional microhemorrhages. Stroke 2017;48:2881–84 doi:10.1161/STROKEAHA.117.017785 pmid:28855391
    Abstract/FREE Full Text
  12. 12.↵
    1. Li R,
    2. Chen P,
    3. Han H, et al
    . Association of nidus size and rupture in brain arteriovenous malformations: Insight from angioarchitecture and hemodynamics. Neurosurg Rev 2023;46:216 doi:10.1007/s10143-023-02113-1 pmid:37650957
    CrossRefPubMed
  13. 13.↵
    1. Wang J,
    2. Cheng JJ,
    3. Huang KY, et al
    . Quantitative assessment of angiographic perfusion reduction using color-coded digital subtraction angiography during transarterial chemoembolization. Abdom Radiology (NY) 2016;41:545–52 doi:10.1007/s00261-015-0622-6 pmid:27039326
    CrossRefPubMed
  14. 14.↵
    1. Atkinson RP,
    2. Awad IA,
    3. Batjer HH, et al
    ; Joint Writing Group of the Technology Assessment Committee American Society of Interventional and Therapeutic Neuroradiology; Joint Section on Cerebrovascular Neurosurgery a Section of the American Association of Neurological Surgeons and Congress of Neurological Surgeons; Section of Stroke and the Section of Interventional Neurology of the American Academy of Neurology. Reporting terminology for brain arteriovenous malformation clinical and radiographic features for use in clinical trials. Stroke 2001;32:1430–42 doi:10.1161/01.str.32.6.1430 pmid:11387510
    Abstract/FREE Full Text
  15. 15.↵
    1. Lv X,
    2. Wu Z,
    3. Jiang C, et al
    . Angioarchitectural characteristics of brain arteriovenous malformations with and without hemorrhage. World Neurosurg 2011;76:95–99 doi:10.1016/j.wneu.2011.01.044 pmid:21839959
    CrossRefPubMedWeb of Science
  16. 16.↵
    1. Dautry R,
    2. Edjlali M,
    3. Roca P, et al
    . Interest of HYPR flow dynamic MRA for characterization of cerebral arteriovenous malformations: comparison with TRICKS MRA and catheter DSA. Eur Radiol 2015;25:3230–37 doi:10.1007/s00330-015-3745-9 pmid:25916388
    CrossRefPubMed
  17. 17.↵
    1. Todaka T,
    2. Hamada J,
    3. Kai Y, et al
    . Analysis of mean transit time of contrast medium in ruptured and unruptured arteriovenous malformations: a digital subtraction angiographic study. Stroke 2003;34:2410–14 doi:10.1161/01.STR.0000089924.43363.E3 pmid:12970520
    Abstract/FREE Full Text
  18. 18.↵
    1. Feghali J,
    2. Yang W,
    3. Xu R, et al
    . R2eD AVM score. Stroke 2019;50:1703–10 doi:10.1161/STROKEAHA.119.025054 pmid:31167618
    CrossRefPubMed
  19. 19.↵
    1. Chen Y,
    2. Han H,
    3. Meng X, et al
    . Development and validation of a scoring system for hemorrhage risk in brain arteriovenous malformations. JAMA Netw Open 2023;6:e231070 doi:10.1001/jamanetworkopen.2023.1070 pmid:36857052
    CrossRefPubMed
  20. 20.↵
    1. Benson JC,
    2. Chiu S,
    3. Flemming K, et al
    . MR characteristics of unruptured intracranial arteriovenous malformations associated with seizure as initial clinical presentation. J Neurointerv Surg 2020;12:186–91 doi:10.1136/neurintsurg-2019-015021 pmid:31320549
    Abstract/FREE Full Text
  21. 21.↵
    1. Scharf J,
    2. Brauherr E,
    3. Forsting M, et al
    . Significance of haemorrhagic lacunes on MRI in patients with hypertensive cerebrovascular disease and intracerebral haemorrhage. Neuroradiology 1994;36:504–08 doi:10.1007/BF00593508 pmid:7845571
    CrossRefPubMedWeb of Science
  22. 22.↵
    1. Chen CW,
    2. Wong HF,
    3. Ye YL, et al
    . Quantitative flow measurement after placing a flow diverter for a distal internal carotid artery aneurysm. J Neurointerv Surg 2017;9:1238–42 doi:10.1136/neurintsurg-2016-012730 pmid:27932668
    Abstract/FREE Full Text
  23. 23.↵
    1. Chen Y,
    2. Ma L,
    3. Yang S, et al
    . Quantitative angiographic hemodynamic evaluation after revascularization surgery for moyamoya disease. Transl Stroke Res 2020;11:871–81 doi:10.1007/s12975-020-00781-5 pmid:32056157
    CrossRefPubMed
  24. 24.↵
    1. Raoult H,
    2. Bannier E,
    3. Maurel P, et al
    . Hemodynamic quantification in brain arteriovenous malformations with time-resolved spin-labeled magnetic resonance angiography. Stroke 2014;45:2461–64 doi:10.1161/STROKEAHA.114.006080 pmid:24984747
    Abstract/FREE Full Text
  25. 25.↵
    1. Kramer H,
    2. Michaely HJ,
    3. Requardt M, et al
    . Effects of injection rate and dose on image quality in time-resolved magnetic resonance angiography (MRA) by using 1.0M contrast agents. Eur Radiol 2007;17:1394–402 doi:10.1007/s00330-006-0493-x pmid:17115161
    CrossRefPubMed
  26. 26.↵
    1. Kim H,
    2. Salman RA,
    3. McCulloch CE, et al
    ; MARS Coinvestigators. Untreated brain arteriovenous malformation. Neurology 2014;83:590–97 doi:10.1212/WNL.0000000000000688 pmid:25015366
    Abstract/FREE Full Text
  27. 27.↵
    1. Hernesniemi JA,
    2. Dashti R,
    3. Juvela S, et al
    . Natural history of brain arteriovenous malformations: a long-term follow-up study of risk of hemorrhage in 238 patients. Neurosurgery 2008;63:823 doi:10.1227/01.NEU.0000330401.82582.5E pmid:19005371
    CrossRefPubMedWeb of Science
  28. 28.↵
    1. Ai X,
    2. Ye Z,
    3. Xu J, et al
    . The factors associated with hemorrhagic presentation in children with untreated brain arteriovenous malformation: a meta-analysis. J Neurosurg Pediatr 2018;23:343–54 doi:10.3171/2018.9.PEDS18262 pmid:30544349
    CrossRefPubMed
  29. 29.↵
    1. Chen Y,
    2. Meng X,
    3. Ma L, et al
    . Contemporary management of brain arteriovenous malformations in mainland China: a Web-based nationwide questionnaire survey. Chin Neurosurg J 2020;6:26 doi:10.1186/s41016-020-00206-0 pmid:32922955
    CrossRefPubMed
  30. 30.↵
    1. Kim H,
    2. Su H,
    3. Weinsheimer S, et al
    . Brain arteriovenous malformation pathogenesis: a response-to-injury paradigm. Acta Neurochir Suppl 2011;111:83–92 doi:10.1007/978-3-7091-0693-8_14 pmid:21725736
    CrossRefPubMed
  31. 31.↵
    1. Frösen J,
    2. Cebral J,
    3. Robertson AM, et al
    . Flow-induced, inflammation-mediated arterial wall remodeling in the formation and progression of intracranial aneurysms. Neurosurg Focus 2019;47:E21 doi:10.3171/2019.5.FOCUS19234 pmid:31261126
    CrossRefPubMed
  32. 32.↵
    1. Fry DL
    . Acute vascular endothelial changes associated with increased blood velocity gradients. Circ Res 1968;22:165–97 doi:10.1161/01.res.22.2.165 pmid:5639037
    Abstract/FREE Full Text
PreviousNext
Back to top
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Lesion-Filling Index from Quantitative DSA Correlates with Hemorrhage of Cerebral AVM
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
Ruinan Li, Yu Chen, Pingting Chen, Li Ma, Heze Han, Zhipeng Li, Wanting Zhou, Xiaolin Chen, Yuanli Zhao
Lesion-Filling Index from Quantitative DSA Correlates with Hemorrhage of Cerebral AVM
American Journal of Neuroradiology May 2024, DOI: 10.3174/ajnr.A8218

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Lesion-Filling Index from Quantitative DSA Correlates with Hemorrhage of Cerebral AVM
Ruinan Li, Yu Chen, Pingting Chen, Li Ma, Heze Han, Zhipeng Li, Wanting Zhou, Xiaolin Chen, Yuanli Zhao
American Journal of Neuroradiology May 2024, DOI: 10.3174/ajnr.A8218
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • CONCLUSIONS
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Crossref (1)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Lesion filling index predicts brain arteriovenous malformation obliteration after Gamma knife radiosurgery: a hemodynamic analysis
    Ruinan Li, Yu Chen, Pingting Chen, Li Ma, Heze Han, Zhipeng Li, Wanting Zhou, Yu Zhou, Minhan Wang, Shibin Sun, Yuanli Zhao, Xiaolin Chen
    Neurosurgical Review 2024 47 1

More in this TOC Section

  • Effect of SARS-CoV2 on Endovascular Thrombectomy
  • Transophthalmic Artery Embolization of Meningiomas
  • Factors Associated with Major Re-recanalization
Show more Neurointervention

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire